SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q0p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 4 VAL A 310
TRP A 296
TRP A 309
 None
 1.37A 1gmkA-1q0pA:
undetectable
1gmkB-1q0pA:
undetectable		 1gmkA-1q0pA:
17.02
1gmkB-1q0pA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 4 VAL A 310
TRP A 296
TRP A 309
 None
 1.12A 1gmkC-1q0pA:
undetectable
1gmkD-1q0pA:
undetectable		 1gmkC-1q0pA:
17.02
1gmkD-1q0pA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 7 GLY A 365
HIS A 367
THR A 363
ILE A 414
 None
 0.86A 1gtnF-1q0pA:
undetectable
1gtnG-1q0pA:
undetectable		 1gtnF-1q0pA:
13.90
1gtnG-1q0pA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 7 GLY A 365
HIS A 367
THR A 363
ILE A 414
 None
 0.81A 1gtnJ-1q0pA:
undetectable
1gtnK-1q0pA:
undetectable		 1gtnJ-1q0pA:
13.90
1gtnK-1q0pA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 8 GLY A 365
HIS A 367
THR A 363
ILE A 414
 None
 0.79A 1gtnP-1q0pA:
undetectable
1gtnQ-1q0pA:
undetectable		 1gtnP-1q0pA:
13.90
1gtnQ-1q0pA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 5 SER A 253
SER A 255
THR A 328
ASN A 368
 MN  A 500 (-2.1A)
MN  A 500 (-2.1A)
MN  A 500 (-2.8A)
None
 0.24A 1yvpA-1q0pA:
11.0		 1yvpA-1q0pA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 6 SER A 253
SER A 255
THR A 328
ASN A 368
 MN  A 500 (-2.1A)
MN  A 500 (-2.1A)
MN  A 500 (-2.8A)
None
 0.26A 1yvpB-1q0pA:
7.9		 1yvpB-1q0pA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 7 SER A 253
SER A 255
THR A 328
ASN A 368
 MN  A 500 (-2.1A)
MN  A 500 (-2.1A)
MN  A 500 (-2.8A)
None
 0.24A 2i91A-1q0pA:
10.7		 2i91A-1q0pA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 7 SER A 253
SER A 255
THR A 328
ASN A 368
 MN  A 500 (-2.1A)
MN  A 500 (-2.1A)
MN  A 500 (-2.8A)
None
 0.25A 2i91B-1q0pA:
9.7		 2i91B-1q0pA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.77A 4k8cA-1q0pA:
undetectable		 4k8cA-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.80A 4kahA-1q0pA:
undetectable		 4kahA-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.79A 4kahB-1q0pA:
undetectable		 4kahB-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.78A 4kanA-1q0pA:
undetectable		 4kanA-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.76A 4kanB-1q0pA:
undetectable		 4kanB-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.79A 4kbeA-1q0pA:
undetectable		 4kbeA-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.79A 4kbeB-1q0pA:
undetectable		 4kbeB-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.76A 4lbgA-1q0pA:
undetectable		 4lbgA-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 SER A 342
TYR A 338
PRO A 349
 None
 0.78A 4lbgB-1q0pA:
undetectable		 4lbgB-1q0pA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 ASP A 251
ASN A 260
SER A 326
 MN  A 500 ( 4.0A)
None
None
 0.73A 4obwA-1q0pA:
undetectable		 4obwA-1q0pA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		3 / 3 ASP A 364
ASP A 251
ASN A 329
 MN  A 500 ( 4.0A)
MN  A 500 ( 4.0A)
None
 0.66A 4q5mA-1q0pA:
undetectable		 4q5mA-1q0pA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 8 THR A 328
ASN A 413
PRO A 373
TYR A 289
 MN  A 500 (-2.8A)
None
None
None
 1.18A 5v4vA-1q0pA:
undetectable		 5v4vA-1q0pA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 1q0p COMPLEMENT FACTOR B
(Homo
sapiens) 		4 / 8 THR A 328
ASN A 413
PRO A 373
TYR A 289
 MN  A 500 (-2.8A)
None
None
None
 1.17A 5v4vB-1q0pA:
undetectable		 5v4vB-1q0pA:
21.17