SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 149
 None
 1.32A 1dsdC-1q0yH:
undetectable		 1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.27A 1dsdC-1q0yH:
undetectable		 1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 116
PRO H 118
THR H 117
PRO H 149
 None
 1.32A 1dsdC-1q0yH:
undetectable		 1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 149
THR H 116
PRO H 118
 None
 1.27A 1dsdC-1q0yH:
undetectable		 1dsdC-1q0yH:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.09A 1usqA-1q0yH:
undetectable		 1usqA-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqB-1q0yH:
undetectable		 1usqB-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqC-1q0yH:
undetectable		 1usqC-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.79A 1usqD-1q0yH:
undetectable		 1usqD-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqE-1q0yH:
undetectable		 1usqE-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.08A 1usqF-1q0yH:
undetectable		 1usqF-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 12 ASP H  86
PHE H  63
MET H  80
PHE H  69
GLY H  65
 None
 1.24A 2fqyA-1q0yH:
undetectable		 2fqyA-1q0yH:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.85A 2jkjA-1q0yH:
undetectable		 2jkjA-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.85A 2jkjB-1q0yH:
undetectable		 2jkjB-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.85A 2jkjC-1q0yH:
undetectable		 2jkjC-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.10A 2jkjE-1q0yH:
undetectable		 2jkjE-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.10A 2jklA-1q0yH:
undetectable		 2jklA-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.84A 2jklB-1q0yH:
undetectable		 2jklB-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.11A 2jklC-1q0yH:
undetectable		 2jklC-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.10A 2jklD-1q0yH:
undetectable		 2jklD-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.11A 2jklE-1q0yH:
undetectable		 2jklE-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.10A 2jklF-1q0yH:
undetectable		 2jklF-1q0yH:
20.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.38A 4m7kH-1q0yH:
24.3		 4m7kH-1q0yH:
71.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 178
ASP H 183
 None
 0.82A 5mthA-1q0yH:
23.7		 5mthA-1q0yH:
75.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 1q0y FAB 9B1, HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASN H  76
ALA H  24
PRO H  52
TYR H  27
 None
 1.05A 5umd2-1q0yH:
undetectable
5umdF-1q0yH:
undetectable		 5umd2-1q0yH:
15.67
5umdF-1q0yH:
15.84