SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q14'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ASN A 116
PHE A  96
VAL A  31
 None
 0.86A 1kijA-1q14A:
undetectable		 1kijA-1q14A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  16
VAL A 278
TRP A 283
 None
 0.91A 1nruA-1q14A:
undetectable		 1nruA-1q14A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  16
VAL A 278
TRP A 283
 None
 0.91A 1nruB-1q14A:
undetectable		 1nruB-1q14A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 102
LEU A 109
MET A  19
 None
 0.81A 1ya3B-1q14A:
0.1		 1ya3B-1q14A:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 6 ALA A  33
SER A  36
ASN A 116
ILE A 117
ASP A 118
 None
 0.15A 1yc2A-1q14A:
19.2		 1yc2A-1q14A:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  33
ASN A 116
ILE A 117
ASP A 118
 None
 0.24A 1yc2D-1q14A:
19.0		 1yc2D-1q14A:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 7 ALA A  33
SER A  36
ASN A 116
ILE A 117
ASP A 118
 None
 0.21A 1yc5A-1q14A:
23.5		 1yc5A-1q14A:
34.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 102
MET A  19
LEU A 277
ILE A  35
 None
 0.90A 1z95A-1q14A:
undetectable		 1z95A-1q14A:
20.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  33
ASN A 116
ILE A 117
ASP A 118
 None
 0.28A 2h4jA-1q14A:
19.5		 2h4jA-1q14A:
34.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 8 ALA A 274
LEU A  99
LEU A 100
ILE A  35
VAL A 112
 None
 1.19A 2uxpA-1q14A:
undetectable		 2uxpA-1q14A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 GLN A 304
GLU A 186
PHE A 138
PRO A 179
 None
 1.36A 3ql6A-1q14A:
undetectable		 3ql6A-1q14A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 181
PHE A 183
GLU A  85
THR A  81
LEU A 159
 None
 1.45A 3ua5A-1q14A:
undetectable		 3ua5A-1q14A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 116
ALA A  33
GLY A  32
THR A 224
 None
 1.29A 4bboC-1q14A:
undetectable		 4bboC-1q14A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 102
MET A  19
LEU A 277
ILE A  35
 None
 0.86A 4ojbA-1q14A:
undetectable		 4ojbA-1q14A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 102
MET A  19
LEU A 277
ILE A  35
 None
 0.91A 4okwA-1q14A:
undetectable		 4okwA-1q14A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 GLY A  32
PRO A 235
THR A 224
THR A 114
 None
 1.28A 5h5fA-1q14A:
0.8		 5h5fA-1q14A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1q14 HST2 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 219
ARG A 111
TYR A 113
TRP A 196
 None
 1.08A 5umwB-1q14A:
0.0
5umwE-1q14A:
0.0		 5umwB-1q14A:
12.47
5umwE-1q14A:
12.47