SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 186
GLY A 184
THR A 243
ILE A 247
 None
 0.60A 1gtnC-1q1nA:
undetectable
1gtnD-1q1nA:
undetectable		 1gtnC-1q1nA:
12.78
1gtnD-1q1nA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ALA A 201
GLY A 223
ILE A 321
ILE A 319
 None
 0.64A 1hshD-1q1nA:
undetectable		 1hshD-1q1nA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ASP A  49
SER A  48
ILE A 191
GLY A 165
GLY A  94
 None
ZN  A1502 (-3.2A)
None
None
None
 1.12A 1mehA-1q1nA:
undetectable		 1mehA-1q1nA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 316
LEU A 310
LEU A 313
LEU A 311
 None
 1.15A 1np1A-1q1nA:
undetectable		 1np1A-1q1nA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 4 SER A 295
ILE A 296
VAL A 249
THR A 167
 None
 1.09A 1u70A-1q1nA:
1.8		 1u70A-1q1nA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  70
GLY A  92
VAL A 314
PRO A 160
ILE A 321
 None
 1.20A 1zq9A-1q1nA:
5.7		 1zq9A-1q1nA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  37
PHE A   7
ARG A 140
 None
 0.78A 2a3aA-1q1nA:
undetectable		 2a3aA-1q1nA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 311
ILE A 153
LEU A 157
SER A 155
 None
 0.98A 2byoA-1q1nA:
0.0		 2byoA-1q1nA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 186
VAL A 273
ASP A 242
 None
 0.77A 2fumD-1q1nA:
undetectable		 2fumD-1q1nA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 188
GLY A 223
ALA A 224
ILE A 198
VAL A 208
 None
 1.12A 2fxdA-1q1nA:
undetectable		 2fxdA-1q1nA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LYS A  29
TYR A  32
PRO A  30
 None
 1.22A 2j9cC-1q1nA:
undetectable		 2j9cC-1q1nA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 136
GLY A 134
VAL A 141
VAL A  71
GLY A  72
 None
 0.97A 2qe6B-1q1nA:
4.0		 2qe6B-1q1nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 9 VAL A 328
VAL A  45
GLY A  67
LEU A 326
ILE A  10
ALA A 336
 None
 1.38A 2z0yA-1q1nA:
2.9		 2z0yA-1q1nA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 9 VAL A 328
VAL A  45
GLY A  67
LEU A 326
ILE A  10
ALA A 336
 None
 1.41A 2z0yB-1q1nA:
3.2		 2z0yB-1q1nA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ARG A 348
ILE A 191
GLY A 192
LEU A 246
ILE A 198
 None
 1.44A 3adsA-1q1nA:
0.0		 3adsA-1q1nA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  34
LEU A  85
PHE A 145
HIS A 142
LEU A 101
 None
 1.44A 3adsA-1q1nA:
0.0		 3adsA-1q1nA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 296
ILE A 185
LEU A 286
MET A 262
 None
 1.16A 3adsA-1q1nA:
0.0		 3adsA-1q1nA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.83A 3aicA-1q1nA:
2.6		 3aicA-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.84A 3aicB-1q1nA:
undetectable		 3aicB-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.83A 3aicE-1q1nA:
undetectable		 3aicE-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.82A 3aicF-1q1nA:
undetectable		 3aicF-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.77A 3aicG-1q1nA:
1.9		 3aicG-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 254
TRP A  57
TYR A 298
 None
 0.84A 3aicH-1q1nA:
2.3		 3aicH-1q1nA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 12 TYR A   3
GLY A  72
GLY A  92
ALA A 158
ASP A  37
VAL A  75
 None
 1.41A 3dmfA-1q1nA:
7.7		 3dmfA-1q1nA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  35
ILE A  36
VAL A 146
VAL A  93
 None
 0.78A 3fi0B-1q1nA:
undetectable		 3fi0B-1q1nA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  35
ILE A  36
VAL A 146
VAL A  93
 None
 0.76A 3fi0G-1q1nA:
undetectable		 3fi0G-1q1nA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  35
ILE A  36
VAL A 146
VAL A  93
 None
 0.78A 3fi0I-1q1nA:
undetectable		 3fi0I-1q1nA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  35
ILE A  36
VAL A 146
VAL A  93
 None
 0.77A 3fi0Q-1q1nA:
undetectable		 3fi0Q-1q1nA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 113
LEU A 310
LEU A 166
SER A 303
SER A 299
 None
 1.25A 3m7rA-1q1nA:
undetectable		 3m7rA-1q1nA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 168
GLY A 165
ILE A 321
GLY A 195
 None
 0.75A 3n9jB-1q1nA:
undetectable		 3n9jB-1q1nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  68
GLY A  67
ILE A 275
GLY A  47
SER A 299
 ZN  A1502 (-3.5A)
None
None
None
None
 1.01A 3sudB-1q1nA:
undetectable		 3sudB-1q1nA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 12 VAL A 352
GLY A 353
VAL A 333
ILE A 149
ALA A 159
ALA A 158
 None
 1.28A 3sufD-1q1nA:
undetectable		 3sufD-1q1nA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 ASP A  49
VAL A 345
GLY A 190
ILE A 191
 None
 0.84A 3ufnB-1q1nA:
undetectable		 3ufnB-1q1nA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 136
PHE A 358
ASN A 137
ILE A  50
ASP A  49
 None
 1.50A 3welA-1q1nA:
undetectable		 3welA-1q1nA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 PHE A   7
VAL A 328
ILE A  10
 None
 0.57A 4emaA-1q1nA:
undetectable		 4emaA-1q1nA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A  75
GLY A  88
LYS A  73
 None
 0.78A 4k50A-1q1nA:
undetectable		 4k50A-1q1nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A  75
GLY A  88
LYS A  73
 None
 0.72A 4k50E-1q1nA:
undetectable		 4k50E-1q1nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 188
GLY A 223
ALA A 224
ASP A 225
ILE A 198
 None
 1.13A 4njtD-1q1nA:
undetectable		 4njtD-1q1nA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 168
LEU A 172
VAL A 248
 None
 0.59A 4wq4A-1q1nA:
undetectable		 4wq4A-1q1nA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 186
ASP A 258
ASN A 260
MET A 262
ILE A 272
 None
 1.20A 4xe0A-1q1nA:
undetectable		 4xe0A-1q1nA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 191
LEU A 188
GLY A 187
THR A 206
VAL A 345
 None
 1.08A 5x66F-1q1nA:
0.0		 5x66F-1q1nA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 THR A 255
GLU A 282
HIS A  51
 None
 0.86A 5xioA-1q1nA:
3.5		 5xioA-1q1nA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 THR A 255
GLU A 282
HIS A  51
 None
 0.84A 5xiqD-1q1nA:
2.8		 5xiqD-1q1nA:
21.29