SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 841
ILE A 762
ALA A 837
ILE A 816
 None
 0.61A 1oniB-1q1oA:
undetectable
1oniC-1q1oA:
undetectable		 1oniB-1q1oA:
17.39
1oniC-1q1oA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 853
SER A 767
LEU A 794
ILE A 802
 None
 0.90A 3ln1A-1q1oA:
undetectable		 3ln1A-1q1oA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 853
SER A 767
LEU A 794
ILE A 802
 None
 0.90A 3ln1B-1q1oA:
undetectable		 3ln1B-1q1oA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 854
ILE A 816
ILE A 813
TYR A 768
ILE A 802
 None
 1.26A 3p4wA-1q1oA:
0.0		 3p4wA-1q1oA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.75A 4ac9C-1q1oA:
undetectable		 4ac9C-1q1oA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.80A 4acaC-1q1oA:
undetectable		 4acaC-1q1oA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 798
ILE A 795
PHE A 791
GLY A 829
 None
 0.79A 4acbC-1q1oA:
undetectable		 4acbC-1q1oA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 841
MET A 840
ASP A 793
 None
 0.71A 4j7xB-1q1oA:
undetectable		 4j7xB-1q1oA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 1q1o CELL DIVISION
CONTROL PROTEIN 24
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 854
ILE A 816
ILE A 813
TYR A 768
ILE A 802
 None
 1.35A 5mzrD-1q1oA:
0.0		 5mzrD-1q1oA:
22.11