SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1q1p EPITHELIAL-CADHERIN
(Mus
musculus) 		4 / 4 ILE A 209
LEU A 189
VAL A 191
ALA A 194
 None
 0.99A 1mz9A-1q1pA:
undetectable		 1mz9A-1q1pA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 1q1p EPITHELIAL-CADHERIN
(Mus
musculus) 		5 / 10 TYR A  74
ILE A  75
ILE A   7
GLU A  93
ILE A  94
 None
 1.19A 2dm6A-1q1pA:
undetectable
2dm6B-1q1pA:
undetectable		 2dm6A-1q1pA:
23.56
2dm6B-1q1pA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1q1p EPITHELIAL-CADHERIN
(Mus
musculus) 		4 / 8 ILE A   7
PHE A  51
LEU A  21
LEU A  66
 None
 0.94A 4qopC-1q1pA:
undetectable		 4qopC-1q1pA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1q1p EPITHELIAL-CADHERIN
(Mus
musculus) 		5 / 12 LEU A  66
ILE A  52
ILE A  94
LEU A  76
GLY A  42
 None
 1.02A 4r3aB-1q1pA:
undetectable		 4r3aB-1q1pA:
20.66