SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 8 LEU A 241
VAL A 164
LEU A  53
ALA A 171
 None
 0.82A 1fiqC-1q1rA:
undetectable		 1fiqC-1q1rA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 THR A 210
LEU A 178
GLY A 156
LEU A 162
 None
 0.94A 1gtiA-1q1rA:
undetectable		 1gtiA-1q1rA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 THR A 210
LEU A 178
GLY A 156
LEU A 162
 None
 0.96A 1gtiE-1q1rA:
undetectable		 1gtiE-1q1rA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 6 ASP A 284
GLY A  11
ILE A   9
ILE A 266
 FAD  A 749 (-2.7A)
FAD  A 749 (-3.0A)
None
None
 0.86A 1n49D-1q1rA:
undetectable		 1n49D-1q1rA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 8 THR A 274
THR A 110
LEU A 260
VAL A  10
 None
FAD  A 749 (-4.2A)
None
None
 0.88A 1t86A-1q1rA:
undetectable		 1t86A-1q1rA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 ALA A 165
GLY A 161
SER A  49
ALA A 168
ILE A 208
 None
None
FAD  A 749 (-3.5A)
None
None
 1.19A 1ve3A-1q1rA:
4.0		 1ve3A-1q1rA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 THR A 212
ILE A 155
VAL A 153
VAL A 214
LEU A 237
 None
 1.22A 1z9hD-1q1rA:
undetectable		 1z9hD-1q1rA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		3 / 3 ALA A 181
GLY A 158
SER A 194
 None
 0.59A 2ivuA-1q1rA:
undetectable		 2ivuA-1q1rA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 GLY A 156
GLY A 157
VAL A 214
LEU A 117
 None
 0.67A 2oa1B-1q1rA:
11.0		 2oa1B-1q1rA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 PHE A 329
LEU A 185
VAL A 188
THR A 189
 None
 0.91A 2qblA-1q1rA:
undetectable		 2qblA-1q1rA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 11 ALA A  15
ILE A 312
ALA A 286
ALA A 281
VAL A 107
 FAD  A 749 (-3.3A)
None
None
None
None
 1.14A 2qhfA-1q1rA:
undetectable		 2qhfA-1q1rA:
26.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 9 LEU A 133
ILE A 160
GLY A 161
GLY A 156
LEU A 248
 FAD  A 749 ( 4.4A)
FAD  A 749 (-4.5A)
None
None
None
 1.16A 2qmmA-1q1rA:
undetectable		 2qmmA-1q1rA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 ILE A 243
LYS A 170
LYS A  56
GLY A  55
 None
 1.19A 3sj0X-1q1rA:
undetectable		 3sj0X-1q1rA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 THR A 110
GLY A 112
PRO A 250
ASN A 251
 FAD  A 749 (-4.2A)
FAD  A 749 (-4.6A)
None
FAD  A 749 ( 4.6A)
 0.69A 3tajA-1q1rA:
undetectable		 3tajA-1q1rA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 5 THR A 110
GLY A 112
PRO A 250
ASN A 251
 FAD  A 749 (-4.2A)
FAD  A 749 (-4.6A)
None
FAD  A 749 ( 4.6A)
 0.70A 3u8qA-1q1rA:
undetectable		 3u8qA-1q1rA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 LEU A 152
ILE A 155
GLY A 161
GLY A 156
LEU A  53
 None
 1.19A 3uj7B-1q1rA:
2.6		 3uj7B-1q1rA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 8 LEU A 241
VAL A 164
LEU A  53
ALA A 171
 None
 0.85A 3uniB-1q1rA:
undetectable		 3uniB-1q1rA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 TYR A  70
GLY A  16
LEU A  77
ALA A 305
PHE A  21
 None
None
None
FAD  A 749 ( 3.8A)
None
 1.23A 3vywB-1q1rA:
2.0		 3vywB-1q1rA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 GLY A  11
GLY A 111
LEU A  78
GLY A  80
PRO A  42
 FAD  A 749 (-3.0A)
FAD  A 749 (-3.1A)
None
None
None
 0.92A 4blvA-1q1rA:
2.0		 4blvA-1q1rA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 6 THR A 110
GLY A 112
PRO A 250
ASN A 251
 FAD  A 749 (-4.2A)
FAD  A 749 (-4.6A)
None
FAD  A 749 ( 4.6A)
 0.68A 4fjpA-1q1rA:
undetectable		 4fjpA-1q1rA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		4 / 7 THR A 110
GLY A 112
PRO A 250
ASN A 251
 FAD  A 749 (-4.2A)
FAD  A 749 (-4.6A)
None
FAD  A 749 ( 4.6A)
 0.68A 4forA-1q1rA:
undetectable		 4forA-1q1rA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 10 PRO A  46
PRO A  67
ALA A  69
PHE A  21
VAL A  17
 FAD  A 749 (-3.6A)
None
None
None
None
 1.02A 5m0oA-1q1rA:
undetectable		 5m0oA-1q1rA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 1q1r PUTIDAREDOXIN
REDUCTASE
(Pseudomonas
putida) 		5 / 12 ALA A 166
LEU A 146
ILE A 142
VAL A 154
ASP A 240
 None
 1.09A 5vlmG-1q1rA:
undetectable		 5vlmG-1q1rA:
19.00