SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 1q1u FIBROBLAST GROWTH
FACTOR HOMOLOGOUS
FACTOR 1
(Homo
sapiens) 		4 / 8 SER A  39
ASN A  38
THR A  34
GLN A  24
 None
 0.88A 1jr1B-1q1uA:
undetectable		 1jr1B-1q1uA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1q1u FIBROBLAST GROWTH
FACTOR HOMOLOGOUS
FACTOR 1
(Homo
sapiens) 		4 / 7 GLN A  24
PHE A  22
ASN A  38
ASP A  36
 None
 1.41A 4kcnB-1q1uA:
0.0		 4kcnB-1q1uA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 1q1u FIBROBLAST GROWTH
FACTOR HOMOLOGOUS
FACTOR 1
(Homo
sapiens) 		3 / 3 HIS A 135
LYS A 129
PHE A  90
 None
 1.49A 5klaA-1q1uA:
undetectable		 5klaA-1q1uA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1q1u FIBROBLAST GROWTH
FACTOR HOMOLOGOUS
FACTOR 1
(Homo
sapiens) 		3 / 3 THR A  42
MET A  25
HIS A  26
 None
 0.96A 5uunA-1q1uA:
undetectable		 5uunA-1q1uA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1q1u FIBROBLAST GROWTH
FACTOR HOMOLOGOUS
FACTOR 1
(Homo
sapiens) 		3 / 3 LYS A 131
PRO A 132
LYS A 117
 SO4  A 439 (-4.6A)
SO4  A 439 (-3.7A)
None
 1.03A 5y9yA-1q1uA:
undetectable		 5y9yA-1q1uA:
19.19