SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		4 / 7 ASP A  36
PHE A  16
SER A  42
ARG A  60
 None
 1.36A 1rqpB-1q2yA:
undetectable		 1rqpB-1q2yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		4 / 7 ASP A  36
PHE A  16
SER A  42
ARG A  60
 None
 1.37A 2v7uB-1q2yA:
undetectable		 2v7uB-1q2yA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		4 / 6 ARG A  58
ASP A 129
ILE A 132
GLN A 109
 None
 1.44A 2ya7C-1q2yA:
undetectable		 2ya7C-1q2yA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		6 / 12 ALA A  89
GLY A  55
GLY A  57
ILE A  71
LEU A  74
ARG A  78
 None
 1.49A 3o7wA-1q2yA:
undetectable		 3o7wA-1q2yA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		3 / 3 GLU A  39
ARG A  58
HIS A  44
 None
 0.86A 4kf9A-1q2yA:
undetectable		 4kf9A-1q2yA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 1q2y SIMILAR TO
HYPOTHETICAL
PROTEINS
(Bacillus
subtilis) 		4 / 7 HIS A 134
ASN A 105
GLU A  69
ARG A  58
 None
 1.19A 6b8kA-1q2yA:
undetectable		 6b8kA-1q2yA:
17.36