SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 253
ARG A 116
PHE A 189
PHE A 262
 None
 1.45A 1e73M-1q32A:
undetectable		 1e73M-1q32A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 265
LEU A 268
LEU A 460
TYR A 487
ILE A 197
 None
 1.11A 1s9pA-1q32A:
undetectable		 1s9pA-1q32A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 317
PHE A 411
MET A 406
SER A 402
 None
 1.19A 1wrlC-1q32A:
undetectable		 1wrlC-1q32A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_A_TPFA2472_1
(CYTOCHROME P450 121)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		5 / 11 THR A 423
VAL A 422
THR A 382
SER A 389
GLN A 213
 None
 1.29A 2ij7A-1q32A:
0.0		 2ij7A-1q32A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_D_TPFD2473_1
(CYTOCHROME P450 121)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		5 / 10 THR A 423
VAL A 422
THR A 382
SER A 389
GLN A 213
 None
 1.21A 2ij7D-1q32A:
0.0		 2ij7D-1q32A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_F_TPFF2474_1
(CYTOCHROME P450 121)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		5 / 10 THR A 423
VAL A 422
THR A 382
SER A 389
GLN A 213
 None
 1.27A 2ij7F-1q32A:
0.0		 2ij7F-1q32A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 325
ASN A 324
LEU A 359
TYR A 436
 None
 1.26A 2w8yA-1q32A:
undetectable		 2w8yA-1q32A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 293
LEU A 199
VAL A 271
LEU A 222
 None
 0.82A 3g8iA-1q32A:
undetectable		 3g8iA-1q32A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 110
ILE A 103
CYH A 216
PHE A 204
 None
 1.05A 3ko0B-1q32A:
undetectable
3ko0J-1q32A:
undetectable		 3ko0B-1q32A:
12.47
3ko0J-1q32A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_B_017B203_1
(PROTEASE)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 5 PRO A 275
LYS A 477
ARG A 479
GLY A 472
 None
 1.50A 3s53B-1q32A:
0.0		 3s53B-1q32A:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 323
ARG A 321
GLN A 468
 None
 0.97A 4rtbA-1q32A:
undetectable		 4rtbA-1q32A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 492
SER A 266
PRO A 232
PHE A 233
 None
 1.14A 5b8iA-1q32A:
undetectable		 5b8iA-1q32A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 1q32 TYROSYL-DNA
PHOSPHODIESTERASE
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 483
LEU A 185
LEU A 237
TYR A 244
HIS A 181
 None
 1.25A 5eb5A-1q32A:
undetectable		 5eb5A-1q32A:
22.48