SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXD_B_RWFB2001_1
(SERUM ALBUMIN)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		5 / 10 LYS A 501
PHE A 548
ARG A 464
LEU A 449
ALA A 425
 None
 1.48A 2bxdB-1q3iA:
undetectable		 2bxdB-1q3iA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 7 LYS A 575
LEU A 576
LEU A 498
PHE A 571
 None
 0.99A 2dysC-1q3iA:
undetectable
2dysJ-1q3iA:
undetectable		 2dysC-1q3iA:
21.77
2dysJ-1q3iA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 7 LYS A 575
LEU A 576
LEU A 498
PHE A 571
 None
 1.06A 2dysP-1q3iA:
undetectable
2dysW-1q3iA:
0.0		 2dysP-1q3iA:
21.77
2dysW-1q3iA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 7 LYS A 575
LEU A 576
LEU A 498
PHE A 571
 None
 1.07A 2eijC-1q3iA:
undetectable
2eijJ-1q3iA:
undetectable		 2eijC-1q3iA:
21.77
2eijJ-1q3iA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 7 GLY A 540
ALA A 382
GLU A 543
GLN A 532
 None
 0.97A 4g0uB-1q3iA:
undetectable		 4g0uB-1q3iA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 6 GLY A 539
ALA A 382
GLU A 543
GLN A 532
 None
 1.12A 4g0uA-1q3iA:
undetectable		 4g0uA-1q3iA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 6 GLY A 540
ALA A 382
GLU A 543
GLN A 532
 None
 0.96A 4g0uA-1q3iA:
undetectable		 4g0uA-1q3iA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		5 / 9 TRP A 411
PHE A 548
ALA A 413
LEU A 414
GLY A 580
 None
 1.23A 4l6va-1q3iA:
undetectable
4l6vf-1q3iA:
undetectable		 4l6va-1q3iA:
13.53
4l6vf-1q3iA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1q3i NA,K-ATPASE
(Sus
scrofa) 		4 / 6 HIS A 486
CYH A 421
HIS A 496
LEU A 498
 None
 1.41A 5hrqH-1q3iA:
undetectable
5hrqK-1q3iA:
undetectable
5hrqL-1q3iA:
undetectable		 5hrqH-1q3iA:
12.11
5hrqK-1q3iA:
7.47
5hrqL-1q3iA:
12.11