SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.57A 5qgjA-1q3oA:
undetectable		 5qgjA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.58A 5qglA-1q3oA:
undetectable		 5qglA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.56A 5qgmA-1q3oA:
undetectable		 5qgmA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.57A 5qgnA-1q3oA:
undetectable		 5qgnA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.52A 5qguA-1q3oA:
undetectable		 5qguA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.47A 5qgvA-1q3oA:
undetectable		 5qgvA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.46A 5qgwA-1q3oA:
undetectable		 5qgwA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.46A 5qgxA-1q3oA:
undetectable		 5qgxA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.45A 5qgyA-1q3oA:
undetectable		 5qgyA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.45A 5qgzA-1q3oA:
undetectable		 5qgzA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.47A 5qh0A-1q3oA:
undetectable		 5qh0A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.45A 5qh1A-1q3oA:
undetectable		 5qh1A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.45A 5qh2A-1q3oA:
undetectable		 5qh2A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.45A 5qh3A-1q3oA:
undetectable		 5qh3A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qh4A-1q3oA:
undetectable		 5qh4A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qh5A-1q3oA:
undetectable		 5qh5A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.48A 5qh6A-1q3oA:
undetectable		 5qh6A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.48A 5qh7A-1q3oA:
undetectable		 5qh7A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qh9A-1q3oA:
undetectable		 5qh9A-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.48A 5qhaA-1q3oA:
undetectable		 5qhaA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qhcA-1q3oA:
undetectable		 5qhcA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qheA-1q3oA:
undetectable		 5qheA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.49A 5qhfA-1q3oA:
undetectable		 5qhfA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.50A 5qhgA-1q3oA:
undetectable		 5qhgA-1q3oA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1q3o SHANK1
(Rattus
norvegicus) 		3 / 3 VAL A 661
VAL A 658
GLN A 656
 None
 0.48A 5qhhA-1q3oA:
undetectable		 5qhhA-1q3oA:
23.59