SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		3 / 3 ARG A 143
ARG A  52
ARG A 193
 None
 1.10A 1l7fA-1q3tA:
undetectable		 1l7fA-1q3tA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		3 / 3 ARG A 143
ARG A  52
ARG A 193
 None
 1.08A 1l7hA-1q3tA:
undetectable		 1l7hA-1q3tA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		5 / 12 MET A  57
THR A  55
VAL A 112
VAL A  97
ILE A  99
 None
 1.36A 3elzA-1q3tA:
undetectable		 3elzA-1q3tA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		4 / 8 ILE A 138
GLN A 130
GLN A  18
ALA A  20
 None
 0.82A 3ozwA-1q3tA:
undetectable		 3ozwA-1q3tA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		5 / 9 LEU A  59
ILE A 115
SER A 113
VAL A 108
THR A  55
 None
 1.43A 4x3mA-1q3tA:
undetectable		 4x3mA-1q3tA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		5 / 12 VAL A 121
GLU A 131
ALA A  53
ALA A  54
GLY A  95
 None
 0.86A 5igjA-1q3tA:
0.0		 5igjA-1q3tA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1q3t CYTIDYLATE KINASE
(Streptococcus
pneumoniae) 		5 / 12 VAL A 121
GLU A 131
ALA A  53
ALA A  54
GLY A  95
 None
 0.87A 5igtA-1q3tA:
undetectable		 5igtA-1q3tA:
22.55