SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 115
GLY A 118
THR A  47
ILE A 201
MET A 167
 None
None
MLA  A 901 (-2.7A)
MLA  A 901 (-4.5A)
None
 1.06A 3ld6B-1q44A:
undetectable		 3ld6B-1q44A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 TYR A  39
GLN A  52
ILE A  24
SER A  36
 None
 1.29A 3pmzD-1q44A:
undetectable		 3pmzD-1q44A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PRO A 204
SER A 320
PHE A 317
ASP A 207
 None
 1.27A 4ndnC-1q44A:
undetectable		 4ndnC-1q44A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PRO A 204
SER A 320
PHE A 317
ASP A 207
 None
 1.26A 4odjA-1q44A:
undetectable		 4odjA-1q44A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 LEU A 136
THR A  72
THR A  78
LEU A  81
 None
 0.85A 4z91F-1q44A:
undetectable
4z91G-1q44A:
undetectable
4z91H-1q44A:
undetectable
4z91I-1q44A:
undetectable
4z91J-1q44A:
undetectable		 4z91F-1q44A:
20.11
4z91G-1q44A:
20.11
4z91H-1q44A:
20.11
4z91I-1q44A:
20.11
4z91J-1q44A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 259
VAL A 256
ILE A 251
GLU A 247
 None
 0.99A 4zzbC-1q44A:
0.0
4zzbD-1q44A:
0.0		 4zzbC-1q44A:
23.24
4zzbD-1q44A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PRO A 204
SER A 320
PHE A 317
ASP A 207
 None
 1.29A 5a1iA-1q44A:
undetectable		 5a1iA-1q44A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 GLY A  12
PRO A   8
THR A  17
GLN A  48
 None
 1.25A 5h5fA-1q44A:
undetectable		 5h5fA-1q44A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 VAL A  35
TYR A  39
GLU A  37
SER A  36
 None
 1.24A 5umwA-1q44A:
0.0
5umwF-1q44A:
0.0		 5umwA-1q44A:
17.43
5umwF-1q44A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 ASP A  65
SER A 154
HIS A 143
VAL A  71
ILE A  69
 None
 1.33A 5y80A-1q44A:
0.0		 5y80A-1q44A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1q44 STEROID
SULFOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 PRO A 204
SER A 320
PHE A 317
ASP A 207
 None
 1.30A 6g6rA-1q44A:
undetectable		 6g6rA-1q44A:
21.53