SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 HIS A 238
ASN A 268
GLY A 203
ASP A 208
VAL A 200
 None
 1.29A 1ffyA-1q50A:
undetectable		 1ffyA-1q50A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 TYR A 560
LEU A 404
LEU A 407
SER A 411
LEU A 372
 None
 1.25A 1ie9A-1q50A:
0.0		 1ie9A-1q50A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 ASN A 381
GLY A 556
ILE A 557
ILE A 377
 None
 0.66A 1n49A-1q50A:
undetectable		 1n49A-1q50A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 6 ASN A 381
GLY A 556
ILE A 557
ILE A 377
 None
 0.66A 1n49D-1q50A:
undetectable		 1n49D-1q50A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 THR A 483
SER A 521
PHE A  75
LEU A 100
 None
 1.14A 1qcaA-1q50A:
undetectable		 1qcaA-1q50A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.86A 1rxcB-1q50A:
undetectable		 1rxcB-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.90A 1rxcC-1q50A:
2.6		 1rxcC-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.85A 1rxcD-1q50A:
2.8		 1rxcD-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.90A 1rxcE-1q50A:
undetectable		 1rxcE-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.88A 1rxcF-1q50A:
2.7		 1rxcF-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.92A 1rxcI-1q50A:
2.6		 1rxcI-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.87A 1rxcK-1q50A:
undetectable		 1rxcK-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.89A 1rxcL-1q50A:
2.6		 1rxcL-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 LEU A 404
ASP A 408
GLY A 376
VAL A 390
 None
 0.77A 2aojB-1q50A:
undetectable		 2aojB-1q50A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 8 GLY A 538
ALA A 542
ALA A 352
TRP A 329
PHE A 348
 None
 1.45A 2ha4A-1q50A:
2.1		 2ha4A-1q50A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLY A 436
PHE A 443
ILE A 447
PHE A 432
 None
 0.95A 2qmzA-1q50A:
2.7
2qmzB-1q50A:
2.6		 2qmzA-1q50A:
18.67
2qmzB-1q50A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 ALA A 256
ALA A 331
VAL A 322
GLY A 323
GLN A 562
 None
 1.27A 2ve3B-1q50A:
0.0		 2ve3B-1q50A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 VAL A 145
ASN A 558
TRP A 563
 None
 0.89A 2y00B-1q50A:
undetectable		 2y00B-1q50A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 LEU A 368
MET A 543
VAL A 390
VAL A 431
PRO A 455
 None
 1.02A 2ygpA-1q50A:
0.0		 2ygpA-1q50A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 PHE A 253
VAL A 200
LEU A 338
SER A 339
 None
 0.91A 3hs6B-1q50A:
undetectable		 3hs6B-1q50A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 8 HIS A 147
VAL A 169
LEU A 173
ARG A 151
LEU A 349
 None
 1.25A 3kp6A-1q50A:
undetectable
3kp6B-1q50A:
undetectable		 3kp6A-1q50A:
13.87
3kp6B-1q50A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 HIS A 227
ASN A 198
ILE A 196
LYS A 223
 None
 1.29A 3kp6A-1q50A:
undetectable
3kp6B-1q50A:
undetectable		 3kp6A-1q50A:
13.87
3kp6B-1q50A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 6 PHE A 318
ALA A 256
THR A 265
THR A 262
 None
 1.12A 3mdrA-1q50A:
0.0		 3mdrA-1q50A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 VAL A 172
PHE A 345
ILE A 541
VAL A 322
VAL A 169
 None
 1.04A 3w68D-1q50A:
undetectable		 3w68D-1q50A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 11 LEU A 397
LEU A 404
GLN A 388
ILE A 540
TYR A 544
 None
 1.37A 4a7aA-1q50A:
undetectable		 4a7aA-1q50A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.81A 4e1vA-1q50A:
2.7		 4e1vA-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.84A 4e1vB-1q50A:
undetectable		 4e1vB-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.82A 4e1vC-1q50A:
2.7		 4e1vC-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.86A 4e1vD-1q50A:
2.5		 4e1vD-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.89A 4e1vE-1q50A:
2.6		 4e1vE-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.79A 4e1vG-1q50A:
undetectable		 4e1vG-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLN A 406
ILE A 332
VAL A 328
PRO A 211
 None
 0.83A 4e1vH-1q50A:
2.6		 4e1vH-1q50A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 ARG A  81
HIS A  74
TYR A  85
 None
 1.22A 4fu8A-1q50A:
undetectable		 4fu8A-1q50A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 ARG A  81
HIS A  74
TYR A  85
 None
 1.19A 4fu9A-1q50A:
undetectable		 4fu9A-1q50A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 LEU A 349
LEU A  91
ASN A 357
 None
 0.74A 4otwA-1q50A:
undetectable		 4otwA-1q50A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 LYS A 129
ALA A 128
GLY A 123
LEU A 549
 None
 0.79A 4po0A-1q50A:
2.2		 4po0A-1q50A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 11 TRP A 188
GLY A 190
PHE A 295
ILE A 310
ASN A 314
 None
 1.26A 4rtrA-1q50A:
4.0		 4rtrA-1q50A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 TRP A 188
GLY A 190
PHE A 295
ILE A 310
ASN A 314
 None
 1.20A 4rtsA-1q50A:
undetectable		 4rtsA-1q50A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 7 ARG A 184
VAL A 183
LEU A 338
SER A 339
 None
 0.97A 4zphA-1q50A:
0.0
4zphB-1q50A:
0.0		 4zphA-1q50A:
23.22
4zphB-1q50A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 ASN A 314
LEU A 338
PHE A 295
 None
 0.74A 5dsgA-1q50A:
undetectable		 5dsgA-1q50A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 ILE A 541
ALA A 542
GLY A 351
GLY A 210
VAL A 214
 None
 1.07A 5i71A-1q50A:
undetectable		 5i71A-1q50A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 LEU A 532
GLY A 210
ALA A 217
LEU A 397
GLY A 333
 None
 1.03A 5kb5A-1q50A:
undetectable		 5kb5A-1q50A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.93A 5wz1A-1q50A:
undetectable		 5wz1A-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.95A 5wz1C-1q50A:
undetectable		 5wz1C-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.95A 5wz1D-1q50A:
undetectable		 5wz1D-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.95A 5wz1E-1q50A:
undetectable		 5wz1E-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.96A 5wz1F-1q50A:
undetectable		 5wz1F-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.95A 5wz1G-1q50A:
undetectable		 5wz1G-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 206
GLY A 210
GLU A 545
ASP A 457
VAL A 390
 None
 0.94A 5wz1H-1q50A:
undetectable		 5wz1H-1q50A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 GLY A 351
ALA A 542
HIS A 546
PRO A 534
THR A 350
 None
 1.04A 5x6yC-1q50A:
2.2		 5x6yC-1q50A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 LEU A 368
LEU A 372
LEU A 528
GLY A 460
 None
 0.84A 6ce2A-1q50A:
undetectable		 6ce2A-1q50A:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		4 / 8 GLY A 538
LEU A 537
VAL A 529
LEU A 400
 None
 0.76A 6czmD-1q50A:
undetectable
6czmF-1q50A:
undetectable		 6czmD-1q50A:
22.77
6czmF-1q50A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 LEU A 298
GLY A 203
ILE A 204
VAL A 322
ILE A 332
 None
 1.01A 6emuA-1q50A:
undetectable		 6emuA-1q50A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 LEU A 298
GLY A 203
ILE A 204
VAL A 322
ILE A 332
 None
 0.97A 6emuB-1q50A:
2.5		 6emuB-1q50A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		5 / 12 LEU A 298
GLY A 203
ILE A 204
VAL A 322
ILE A 332
 None
 0.98A 6emuC-1q50A:
1.0		 6emuC-1q50A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE
(Leishmania
mexicana) 		3 / 3 LEU A  51
ASN A 380
LEU A 118
 None
 0.67A 6exiA-1q50A:
undetectable		 6exiA-1q50A:
10.51