SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1q56 AGRIN
(Gallus
gallus) 		5 / 11 LEU A 143
GLY A 144
PHE A 163
TYR A  27
VAL A 170
 None
 1.37A 1axwB-1q56A:
undetectable		 1axwB-1q56A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 1q56 AGRIN
(Gallus
gallus) 		5 / 10 THR A  23
GLY A  21
GLY A 162
ILE A  17
ALA A  18
 None
 1.14A 1x7pA-1q56A:
undetectable
1x7pB-1q56A:
undetectable		 1x7pA-1q56A:
21.16
1x7pB-1q56A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 1q56 AGRIN
(Gallus
gallus) 		5 / 12 GLY A 145
VAL A  78
ILE A  47
GLY A 165
ILE A 164
 None
 0.82A 2o4sA-1q56A:
undetectable		 2o4sA-1q56A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1q56 AGRIN
(Gallus
gallus) 		3 / 3 ILE A  97
PHE A 163
HIS A 101
 None
 0.70A 3h0aA-1q56A:
undetectable		 3h0aA-1q56A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1q56 AGRIN
(Gallus
gallus) 		5 / 8 GLY A 165
ASP A  20
GLY A 144
ILE A  56
THR A 161
 None
 1.02A 3so9A-1q56A:
undetectable		 3so9A-1q56A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 1q56 AGRIN
(Gallus
gallus) 		3 / 3 LEU A 116
MET A  80
ASP A 169
 None
 0.72A 4j7xB-1q56A:
undetectable		 4j7xB-1q56A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 1q56 AGRIN
(Gallus
gallus) 		5 / 10 TYR A  27
GLY A 165
PHE A  19
GLY A 145
MET A 146
 None
 1.08A 4xpbA-1q56A:
undetectable		 4xpbA-1q56A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1q56 AGRIN
(Gallus
gallus) 		4 / 7 ILE A  56
PHE A 163
VAL A  78
ILE A  97
 None
 0.83A 4zzbC-1q56A:
undetectable
4zzbD-1q56A:
undetectable		 4zzbC-1q56A:
19.63
4zzbD-1q56A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1q56 AGRIN
(Gallus
gallus) 		4 / 6 SER A  40
GLY A  85
ASP A  83
GLY A 131
 None
 0.94A 5cdnC-1q56A:
undetectable
5cdnD-1q56A:
undetectable		 5cdnC-1q56A:
16.94
5cdnD-1q56A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1q56 AGRIN
(Gallus
gallus) 		4 / 8 TRP A 142
GLU A 176
HIS A  28
THR A 188
 None
 1.15A 5hqaA-1q56A:
undetectable		 5hqaA-1q56A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1q56 AGRIN
(Gallus
gallus) 		5 / 12 THR A  23
GLY A  21
GLY A 162
ILE A  17
ALA A  18
 None
 1.02A 5l0zA-1q56A:
undetectable		 5l0zA-1q56A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1q56 AGRIN
(Gallus
gallus) 		5 / 10 THR A  23
GLY A  21
GLY A 162
ILE A  17
ALA A  18
 None
 1.04A 5l0zB-1q56A:
undetectable		 5l0zB-1q56A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1q56 AGRIN
(Gallus
gallus) 		3 / 3 LEU A 141
ALA A 140
LEU A  57
 None
 0.47A 5uunB-1q56A:
undetectable		 5uunB-1q56A:
24.05