SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 ILE A 172
ALA A 207
ILE A 211
PRO A 185
LEU A 179
 None
 0.89A 1dhfA-1q5aA:
undetectable		 1dhfA-1q5aA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLU A 265
TYR A 296
PHE A 268
 None
 0.55A 1eqbB-1q5aA:
undetectable		 1eqbB-1q5aA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLU A 265
TYR A 296
PHE A 268
 None
 0.56A 1eqbA-1q5aA:
undetectable		 1eqbA-1q5aA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLU A 265
TYR A 296
PHE A 268
 None
 0.51A 1eqbD-1q5aA:
undetectable		 1eqbD-1q5aA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLU A 265
TYR A 296
PHE A 268
 None
 0.54A 1eqbC-1q5aA:
undetectable		 1eqbC-1q5aA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 513
PRO A 438
LEU A 522
 None
 0.00A 1hrkA-1q5aA:
undetectable		 1hrkA-1q5aA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 VAL A 117
GLY A 115
ILE A 208
ILE A 165
ILE A 172
 None
None
NAG  A 801 ( 4.7A)
None
None
 0.83A 1hshA-1q5aA:
undetectable		 1hshA-1q5aA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A 325
SER A 418
ASP A 414
ASP A 360
 CA  A 915 (-2.6A)
None
CA  A 912 (-2.5A)
CA  A 912 ( 3.6A)
 0.78A 1m4iA-1q5aA:
undetectable		 1m4iA-1q5aA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ILE A 175
LEU A 174
VAL A 127
 None
 0.37A 1mz9B-1q5aA:
undetectable		 1mz9B-1q5aA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 513
VAL A 511
LEU A 475
 None
 0.00A 1mz9B-1q5aA:
undetectable		 1mz9B-1q5aA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 THR A 407
LEU A 428
LEU A 345
 NAG  A 808 (-2.2A)
None
None
 0.55A 1mz9C-1q5aA:
undetectable		 1mz9C-1q5aA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 THR A  39
LEU A  76
VAL A  75
 None
 0.63A 1mz9E-1q5aA:
undetectable		 1mz9E-1q5aA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 THR A 458
VAL A 439
ASP A 461
ILE A 459
 None
None
CA  A 914 (-2.6A)
None
 0.72A 1p7rA-1q5aA:
undetectable		 1p7rA-1q5aA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 PHE A  51
GLU A  13
LEU A  66
LYS A   8
 None
 0.94A 1rmtB-1q5aA:
undetectable		 1rmtB-1q5aA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 TYR A 148
LEU A 146
ASP A 195
THR A 109
 None
None
CA  A 905 (-2.6A)
None
 1.06A 1rmtD-1q5aA:
undetectable		 1rmtD-1q5aA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A  44
ALA A  43
ILE A  38
ILE A  94
 None
 0.00A 1sh9A-1q5aA:
undetectable		 1sh9A-1q5aA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ILE A 261
ILE A 300
GLY A 280
ILE A 281
 None
 0.08A 1sh9A-1q5aA:
undetectable		 1sh9A-1q5aA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ARG A 114
SER A 149
TYR A 148
 None
 0.54A 1x70A-1q5aA:
undetectable		 1x70A-1q5aA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 312
PHE A 308
ARG A 262
 None
NDG  A 804 (-4.9A)
NAG  A 805 ( 4.6A)
 0.89A 1xdkB-1q5aA:
undetectable		 1xdkB-1q5aA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 ALA A 193
SER A 147
PHE A 108
ILE A 165
 None
 1.02A 1yc2A-1q5aA:
undetectable		 1yc2A-1q5aA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ARG A 347
VAL A 381
GLY A 372
 None
 0.39A 2avvE-1q5aA:
undetectable		 2avvE-1q5aA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ARG A 347
VAL A 388
GLY A 372
 None
 0.60A 2avvE-1q5aA:
undetectable		 2avvE-1q5aA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A  42
ALA A  43
ILE A  53
ILE A  96
ILE A  38
 None
 0.25A 2b60A-1q5aA:
undetectable		 2b60A-1q5aA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 LEU A 189
TYR A 187
ILE A 209
GLY A 176
 None
NAG  A 801 (-4.2A)
None
None
 0.77A 2du8A-1q5aA:
undetectable		 2du8A-1q5aA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 LEU A 189
TYR A 187
ILE A 209
GLY A 176
 None
NAG  A 801 (-4.2A)
None
None
 0.79A 2du8B-1q5aA:
undetectable		 2du8B-1q5aA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASP A 415
ASP A 384
ASP A 358
 None
None
CA  A 912 (-2.7A)
 0.73A 2igtB-1q5aA:
undetectable		 2igtB-1q5aA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 ALA A 193
ALA A 132
THR A 109
PHE A 113
MET A 128
 None
 1.13A 2jjpA-1q5aA:
undetectable		 2jjpA-1q5aA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A 200
GLY A 198
THR A 194
LEU A 146
GLU A 197
 None
 0.00A 2oxtB-1q5aA:
undetectable		 2oxtB-1q5aA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A 200
GLY A 198
THR A 194
LEU A 146
GLU A 197
 None
 0.51A 2oxtC-1q5aA:
undetectable		 2oxtC-1q5aA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 SER A 309
ASP A 180
ASP A 213
 None
CA  A 909 (-2.5A)
CA  A 908 (-2.5A)
 0.00A 2plwA-1q5aA:
undetectable		 2plwA-1q5aA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 SER A 309
ASP A 246
ASP A 216
 None
CA  A 910 (-2.3A)
CA  A 909 ( 2.6A)
 0.00A 2plwA-1q5aA:
undetectable		 2plwA-1q5aA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 513
PRO A 438
LEU A 522
 None
 0.00A 2po5B-1q5aA:
undetectable		 2po5B-1q5aA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 513
PRO A 520
LEU A 522
 None
 0.00A 2po5B-1q5aA:
undetectable		 2po5B-1q5aA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 PHE A 332
VAL A 408
VAL A 381
VAL A 388
 None
 0.00A 2qbnA-1q5aA:
undetectable		 2qbnA-1q5aA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 VAL A 433
ASP A 463
GLU A 343
 CA  A 916 (-3.6A)
CA  A 914 ( 3.4A)
CA  A 913 ( 2.5A)
 0.00A 2qeuA-1q5aA:
undetectable		 2qeuA-1q5aA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 VAL A 433
ASP A 463
GLU A 343
 CA  A 916 (-3.6A)
CA  A 914 ( 3.4A)
CA  A 913 ( 2.5A)
 0.00A 2qeuC-1q5aA:
undetectable		 2qeuC-1q5aA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 GLY A 170
GLY A 198
GLN A 192
PHE A 108
 None
 0.00A 2qwxA-1q5aA:
undetectable
2qwxB-1q5aA:
undetectable		 2qwxA-1q5aA:
13.81
2qwxB-1q5aA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 PHE A 108
LEU A 201
LEU A 146
ALA A 132
 None
 0.00A 2vcvF-1q5aA:
undetectable		 2vcvF-1q5aA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 ALA A 193
ALA A 132
THR A 109
PHE A 113
 None
 1.05A 2xfhA-1q5aA:
undetectable		 2xfhA-1q5aA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 379
ARG A 377
ILE A 371
 None
 0.00A 2xn5B-1q5aA:
undetectable		 2xn5B-1q5aA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 THR A 273
ILE A 271
GLY A 280
PHE A 221
 NAG  A 803 (-2.6A)
None
None
None
 0.00A 2y7wC-1q5aA:
undetectable		 2y7wC-1q5aA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A  40
GLY A  49
GLY A  42
 None
 0.00A 3bogC-1q5aA:
undetectable		 3bogC-1q5aA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A  49
GLY A  40
GLY A  42
 None
 0.00A 3bogC-1q5aA:
undetectable		 3bogC-1q5aA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 348
GLY A 392
GLY A 390
 None
 0.00A 3bogC-1q5aA:
undetectable		 3bogC-1q5aA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 392
GLY A 348
GLY A 390
 None
 0.00A 3bogC-1q5aA:
undetectable		 3bogC-1q5aA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 ALA A 317
LEU A 298
THR A 316
VAL A 302
 None
None
NAG  A 805 ( 2.2A)
None
 0.85A 3d2tA-1q5aA:
undetectable		 3d2tA-1q5aA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.54A 3eeyC-1q5aA:
undetectable		 3eeyC-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.60A 3eeyD-1q5aA:
undetectable		 3eeyD-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.57A 3eeyE-1q5aA:
undetectable		 3eeyE-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.60A 3eeyH-1q5aA:
undetectable		 3eeyH-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.56A 3eeyI-1q5aA:
undetectable		 3eeyI-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 THR A 468
GLY A 437
ASN A 518
ILE A 459
ASN A 467
 None
CA  A 914 ( 4.0A)
None
None
None
 0.57A 3eeyJ-1q5aA:
undetectable		 3eeyJ-1q5aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 437
PRO A 440
LEU A 513
 CA  A 914 ( 4.0A)
None
None
 0.55A 3hcpB-1q5aA:
undetectable		 3hcpB-1q5aA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 LEU A 174
GLY A 115
ALA A 207
ILE A 150
 None
 0.00A 3jusB-1q5aA:
undetectable		 3jusB-1q5aA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASN A 102
ASN A  12
GLU A  69
 CA  A 905 (-3.5A)
CA  A 907 (-3.3A)
CA  A 906 ( 2.4A)
 0.80A 3kpdC-1q5aA:
undetectable		 3kpdC-1q5aA:
10.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASN A 102
ASN A  12
GLU A  69
 CA  A 905 (-3.5A)
CA  A 907 (-3.3A)
CA  A 906 ( 2.4A)
 0.86A 3kpdB-1q5aA:
undetectable		 3kpdB-1q5aA:
10.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLU A  11
GLU A 135
ASN A 104
 CA  A 906 ( 2.9A)
None
None
 0.67A 3lp9B-1q5aA:
undetectable
3lp9D-1q5aA:
undetectable		 3lp9B-1q5aA:
13.72
3lp9D-1q5aA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 PRO A 106
SER A 202
ASN A 102
 None
None
CA  A 905 (-3.5A)
 0.88A 3lslG-1q5aA:
undetectable		 3lslG-1q5aA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 GLU A 182
ASP A 216
ARG A 181
ALA A 214
 CA  A 909 ( 2.5A)
CA  A 909 ( 2.6A)
None
CA  A 908 (-4.7A)
 0.65A 3mbgA-1q5aA:
undetectable
3mbgB-1q5aA:
undetectable		 3mbgA-1q5aA:
8.67
3mbgB-1q5aA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 VAL A 381
VAL A 430
VAL A 408
ILE A 351
 None
 0.00A 3mssD-1q5aA:
undetectable		 3mssD-1q5aA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 9 GLY A  42
ALA A  43
ILE A  53
ILE A  96
ILE A  38
 None
 0.22A 3nu4B-1q5aA:
undetectable		 3nu4B-1q5aA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ALA A 129
GLY A 115
ILE A 209
VAL A 191
 None
 0.00A 3nu9A-1q5aA:
undetectable		 3nu9A-1q5aA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A 216
ASP A 248
PRO A 253
GLU A 119
 CA  A 909 ( 2.6A)
CA  A 908 ( 3.1A)
None
CA  A 909 ( 3.2A)
 0.31A 3oyaA-1q5aA:
undetectable		 3oyaA-1q5aA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A 216
ASP A 248
PRO A 253
GLU A 182
 CA  A 909 ( 2.6A)
CA  A 908 ( 3.1A)
None
CA  A 909 ( 2.5A)
 0.21A 3oyaA-1q5aA:
undetectable		 3oyaA-1q5aA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A 435
ASP A 463
PRO A 466
GLU A 397
 CA  A 913 ( 2.3A)
CA  A 914 ( 3.4A)
None
CA  A 916 ( 1.9A)
 0.89A 3oyaA-1q5aA:
undetectable		 3oyaA-1q5aA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 GLN A 153
TYR A 187
GLN A 210
ILE A 211
 None
NAG  A 801 (-4.2A)
None
None
 1.17A 3peoG-1q5aA:
undetectable		 3peoG-1q5aA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A 120
ASP A 216
ASP A 180
ILE A 209
ILE A 211
 None
CA  A 909 ( 2.6A)
CA  A 909 (-2.5A)
None
None
 0.59A 3s54B-1q5aA:
undetectable		 3s54B-1q5aA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 348
GLY A 390
THR A 380
 None
 0.00A 3si7B-1q5aA:
undetectable		 3si7B-1q5aA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 392
GLY A 390
THR A 380
 None
 0.00A 3si7B-1q5aA:
undetectable		 3si7B-1q5aA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 SER A  82
PHE A  31
LYS A  28
 None
 0.92A 3u88A-1q5aA:
undetectable		 3u88A-1q5aA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLN A 153
PHE A 163
TYR A 187
 None
None
NAG  A 801 (-4.2A)
 0.90A 3ucjB-1q5aA:
undetectable		 3ucjB-1q5aA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASN A 434
ASP A 515
ASN A 518
 CA  A 914 (-2.5A)
CA  A 914 (-3.1A)
None
 0.70A 4agaA-1q5aA:
undetectable		 4agaA-1q5aA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A 115
ILE A 208
ILE A 209
VAL A 127
ILE A 172
 None
NAG  A 801 ( 4.7A)
None
None
None
 0.24A 4ax8A-1q5aA:
undetectable		 4ax8A-1q5aA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A 115
ILE A 208
ILE A 209
VAL A 127
ILE A 172
 None
NAG  A 801 ( 4.7A)
None
None
None
 0.37A 4azvA-1q5aA:
undetectable		 4azvA-1q5aA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A  67
ASN A 104
GLU A  11
ASP A 195
 CA  A 907 (-2.7A)
None
CA  A 906 ( 2.9A)
CA  A 905 (-2.6A)
 1.00A 4gkhC-1q5aA:
undetectable
4gkhK-1q5aA:
undetectable		 4gkhC-1q5aA:
15.27
4gkhK-1q5aA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A  67
ASP A 195
GLU A  11
ASP A 134
 CA  A 907 (-2.7A)
CA  A 905 (-2.6A)
CA  A 906 ( 2.9A)
CA  A 905 (-2.1A)
 1.08A 4gkiE-1q5aA:
undetectable
4gkiG-1q5aA:
undetectable		 4gkiE-1q5aA:
15.27
4gkiG-1q5aA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 ILE A 352
LEU A 354
PHE A 332
GLY A 422
 None
 0.48A 4hajA-1q5aA:
undetectable		 4hajA-1q5aA:
5.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ILE A 352
LEU A 354
PHE A 332
GLY A 422
 None
 0.52A 4hb6A-1q5aA:
undetectable		 4hb6A-1q5aA:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ILE A 352
LEU A 354
PHE A 332
GLY A 422
 None
 0.59A 4hb8A-1q5aA:
undetectable		 4hb8A-1q5aA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 GLN A 299
THR A 318
THR A 301
ARG A 262
 NAG  A 806 (-4.0A)
NAG  A 806 (-2.3A)
NAG  A 805 (-3.4A)
NAG  A 805 ( 4.6A)
 0.84A 4k87A-1q5aA:
undetectable		 4k87A-1q5aA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 GLY A 287
VAL A 230
ALA A 228
LEU A 282
 None
None
NAG  A 812 (-4.9A)
None
 0.00A 4l9iB-1q5aA:
undetectable		 4l9iB-1q5aA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASN A 518
ASP A 463
ASP A 395
 None
CA  A 914 ( 3.4A)
CA  A 913 (-2.1A)
 0.00A 4obwD-1q5aA:
undetectable		 4obwD-1q5aA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 TYR A  74
GLY A  42
PRO A  47
 None
 0.00A 4qwpA-1q5aA:
undetectable		 4qwpA-1q5aA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASN A 434
GLY A 437
VAL A 473
SER A 474
 CA  A 914 (-2.5A)
CA  A 914 ( 4.0A)
None
None
 0.81A 4r20A-1q5aA:
undetectable		 4r20A-1q5aA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 4 ASN A 278
VAL A 302
THR A 245
ILE A 220
 None
None
NAG  A 802 (-2.1A)
NAG  A 802 ( 4.8A)
 1.44A 4retA-1q5aA:
undetectable		 4retA-1q5aA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 4 ASN A 278
VAL A 302
THR A 245
ILE A 220
 None
None
NAG  A 802 (-2.1A)
NAG  A 802 ( 4.8A)
 1.46A 4retC-1q5aA:
undetectable		 4retC-1q5aA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 VAL A 511
LEU A 513
VAL A 473
 None
 0.00A 4wq4A-1q5aA:
undetectable		 4wq4A-1q5aA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 THR A 407
THR A 425
LEU A 426
THR A 405
 NAG  A 808 (-2.2A)
NDG  A 811 (-2.2A)
None
NAG  A 808 ( 4.5A)
 0.65A 4z90A-1q5aA:
undetectable
4z90B-1q5aA:
undetectable
4z90C-1q5aA:
undetectable
4z90D-1q5aA:
undetectable
4z90E-1q5aA:
undetectable		 4z90A-1q5aA:
16.50
4z90B-1q5aA:
16.50
4z90C-1q5aA:
16.50
4z90D-1q5aA:
16.50
4z90E-1q5aA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 THR A 405
THR A 407
THR A 425
LEU A 426
 NAG  A 808 ( 4.5A)
NAG  A 808 (-2.2A)
NDG  A 811 (-2.2A)
None
 0.96A 4z91F-1q5aA:
undetectable
4z91G-1q5aA:
undetectable
4z91H-1q5aA:
undetectable
4z91I-1q5aA:
undetectable
4z91J-1q5aA:
undetectable		 4z91F-1q5aA:
16.50
4z91G-1q5aA:
16.50
4z91H-1q5aA:
16.50
4z91I-1q5aA:
16.50
4z91J-1q5aA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 ALA A 285
ARG A 241
GLY A 280
GLU A 276
 None
 0.00A 5bs8A-1q5aA:
undetectable
5bs8C-1q5aA:
undetectable
5bs8D-1q5aA:
undetectable		 5bs8A-1q5aA:
22.21
5bs8C-1q5aA:
22.21
5bs8D-1q5aA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ASN A 373
LEU A 428
PHE A 332
 None
 0.00A 5dsgA-1q5aA:
undetectable		 5dsgA-1q5aA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 GLY A  42
ALA A  43
ILE A  53
ILE A  96
ILE A  38
 None
 0.71A 5e5kA-1q5aA:
undetectable		 5e5kA-1q5aA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 THR A 273
ALA A 257
ASN A 278
 NAG  A 803 (-2.6A)
None
None
 0.34A 5ersA-1q5aA:
undetectable		 5ersA-1q5aA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 PRO A 106
ILE A  99
SER A 202
 None
 0.00A 5fsaA-1q5aA:
undetectable		 5fsaA-1q5aA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 VAL A 230
ALA A 228
GLN A 240
VAL A 239
 None
NAG  A 812 (-4.9A)
NAG  A 812 (-4.2A)
None
 1.03A 5i8fA-1q5aA:
undetectable		 5i8fA-1q5aA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 10 ILE A  99
VAL A  62
ILE A   7
LEU A  21
PRO A  18
 None
 1.14A 5ienB-1q5aA:
undetectable		 5ienB-1q5aA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 SER A  37
TYR A  36
TYR A  35
 None
 0.00A 5lakA-1q5aA:
0.0
5lakI-1q5aA:
undetectable		 5lakA-1q5aA:
15.02
5lakI-1q5aA:
0.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 SER A  37
TYR A  36
TYR A  35
 None
 0.00A 5lakC-1q5aA:
0.0
5lakJ-1q5aA:
undetectable		 5lakC-1q5aA:
15.02
5lakJ-1q5aA:
0.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 VAL A 401
ILE A 371
ILE A 427
LEU A 426
ILE A 352
 None
 0.62A 5mueA-1q5aA:
undetectable		 5mueA-1q5aA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 ALA A 257
GLN A 279
THR A 273
 None
None
NAG  A 803 (-2.6A)
 0.00A 5n0oA-1q5aA:
undetectable		 5n0oA-1q5aA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 VAL A 473
LEU A 513
ILE A 459
SER A 497
 None
 0.00A 5numA-1q5aA:
undetectable		 5numA-1q5aA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 11 LEU A 242
GLU A 303
SER A 243
THR A 301
ALA A 317
 None
NDG  A 804 ( 4.4A)
None
NAG  A 805 (-3.4A)
None
 0.83A 5o96A-1q5aA:
undetectable
5o96B-1q5aA:
undetectable		 5o96A-1q5aA:
14.27
5o96B-1q5aA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 LEU A 242
SER A 243
PHE A 221
ASP A 222
 None
None
None
NAG  A 802 (-4.4A)
 0.89A 5om3A-1q5aA:
undetectable
5om3B-1q5aA:
0.0		 5om3A-1q5aA:
7.43
5om3B-1q5aA:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 6 PRO A 438
VAL A 511
VAL A 525
ILE A 459
 None
 0.00A 5pbeA-1q5aA:
undetectable		 5pbeA-1q5aA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 VAL A 525
PRO A 440
ILE A 459
THR A 523
 None
 0.00A 5vkqA-1q5aA:
undetectable
5vkqD-1q5aA:
undetectable		 5vkqA-1q5aA:
19.67
5vkqD-1q5aA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 GLY A 144
ASN A 138
ARG A  68
 CA  A 905 ( 4.7A)
None
None
 0.16A 5w7bD-1q5aA:
undetectable		 5w7bD-1q5aA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 426
VAL A 339
ASP A 340
 None
 0.00A 5x23A-1q5aA:
undetectable		 5x23A-1q5aA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 ALA A 132
VAL A 203
ASP A 195
GLY A 198
ALA A 199
 None
None
CA  A 905 (-2.6A)
None
None
 0.59A 5xxiA-1q5aA:
undetectable		 5xxiA-1q5aA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 ASN A 143
ASN A 104
GLU A  69
ARG A  68
 None
None
CA  A 906 ( 2.4A)
None
 0.00A 6b8kA-1q5aA:
undetectable		 6b8kA-1q5aA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASN A 143
ASN A 104
GLU A  69
ARG A  68
 None
None
CA  A 906 ( 2.4A)
None
 0.00A 6b94A-1q5aA:
undetectable		 6b94A-1q5aA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 TYR A 471
GLY A 437
THR A 468
 None
CA  A 914 ( 4.0A)
None
 0.00A 6cjkB-1q5aA:
undetectable		 6cjkB-1q5aA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 LEU A 242
GLN A 279
THR A 273
VAL A 302
 None
None
NAG  A 803 (-2.6A)
None
 0.68A 6czmD-1q5aA:
undetectable
6czmF-1q5aA:
undetectable		 6czmD-1q5aA:
16.91
6czmF-1q5aA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 TYR A 259
ALA A 317
LEU A 242
 None
 0.00A 6d9kF-1q5aA:
undetectable		 6d9kF-1q5aA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 ASP A 111
GLU A 204
VAL A 191
LEU A 151
ILE A 150
 None
 0.00A 6ectA-1q5aA:
undetectable		 6ectA-1q5aA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 12 ASP A 111
GLU A 204
VAL A 191
LEU A 151
ILE A 150
 None
 0.00A 6ecxA-1q5aA:
undetectable		 6ecxA-1q5aA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 354
ASN A 373
LEU A 379
 None
 0.64A 6exiA-1q5aA:
undetectable		 6exiA-1q5aA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 354
ASN A 373
LEU A 428
 None
 0.48A 6exiA-1q5aA:
undetectable		 6exiA-1q5aA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 354
ASN A 391
LEU A 428
 None
 0.00A 6exiA-1q5aA:
undetectable		 6exiA-1q5aA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		3 / 3 LEU A 174
SER A 173
PHE A 163
 None
 0.00A 6fgcA-1q5aA:
undetectable		 6fgcA-1q5aA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 7 ILE A 261
LEU A 298
LEU A 282
LEU A 288
 None
 0.00A 6g9bA-1q5aA:
undetectable
6g9bB-1q5aA:
0.0		 6g9bA-1q5aA:
7.12
6g9bB-1q5aA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 1q5a EP-CADHERIN
(Mus
musculus) 		5 / 11 THR A 322
VAL A 319
PHE A 269
THR A 284
ILE A 235
 None
 0.84A 6hcoA-1q5aA:
undetectable
6hcoB-1q5aA:
undetectable		 6hcoA-1q5aA:
20.95
6hcoB-1q5aA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1q5a EP-CADHERIN
(Mus
musculus) 		4 / 8 ASP A 222
ILE A 220
ASN A 304
TYR A 259
 NAG  A 802 (-4.4A)
NAG  A 802 ( 4.8A)
CA  A 910 (-3.2A)
None
 1.24A 6hisD-1q5aA:
undetectable
6hisE-1q5aA:
undetectable		 6hisD-1q5aA:
6.23
6hisE-1q5aA:
6.23