SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 LEU H  14
GLY H  44
VAL H  87
LEU H 104
LEU H  83
None
1.24A 1mx1B-1q5rH:
undetectable
1mx1B-1q5rH:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 LEU H  14
GLY H  44
VAL H  87
LEU H 104
LEU H  83
None
1.21A 1mx1C-1q5rH:
undetectable
1mx1C-1q5rH:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 LEU H  14
GLY H  44
VAL H  87
LEU H 104
LEU H  83
None
1.19A 1mx1E-1q5rH:
undetectable
1mx1E-1q5rH:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 11 GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.49A 2f16H-1q5rH:
23.8
2f16I-1q5rH:
20.5
2f16H-1q5rH:
27.16
2f16I-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 10 ALA H  20
THR H  21
ALA H  27
VAL H  31
GLY H  47
ALA H  49
None
0.47A 2f16K-1q5rH:
23.8
2f16L-1q5rH:
22.5
2f16K-1q5rH:
27.59
2f16L-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 11 GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.50A 2f16V-1q5rH:
23.8
2f16W-1q5rH:
23.4
2f16V-1q5rH:
27.16
2f16W-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 10 ALA H  20
THR H  21
ALA H  27
VAL H  31
GLY H  47
ALA H  49
None
0.47A 2f16Y-1q5rH:
13.4
2f16Z-1q5rH:
22.3
2f16Y-1q5rH:
27.59
2f16Z-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 LEU H  14
ALA H 167
LEU H 171
ALA H 146
None
0.90A 2vcvG-1q5rH:
undetectable
2vcvG-1q5rH:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLY H  -1
VAL H 195
GLY H  16
ALA H  43
ALA H  42
None
1.11A 3keeB-1q5rH:
undetectable
3keeB-1q5rH:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLY H  -1
VAL H 195
GLY H  16
ALA H  43
ALA H  42
None
1.06A 3keeC-1q5rH:
undetectable
3keeC-1q5rH:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H   1
THR H  21
GLN H  22
GLY H  47
THR H  48
None
1.03A 3mg0H-1q5rH:
23.8
3mg0I-1q5rH:
20.4
3mg0H-1q5rH:
27.16
3mg0I-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.37A 3mg0H-1q5rH:
23.8
3mg0I-1q5rH:
20.4
3mg0H-1q5rH:
27.16
3mg0I-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
8 / 11 ALA H  20
THR H  21
ALA H  27
VAL H  31
ALA H  46
GLY H  47
ALA H  49
SER H 141
None
0.53A 3mg0K-1q5rH:
23.9
3mg0L-1q5rH:
22.5
3mg0K-1q5rH:
27.59
3mg0L-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 11 GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.40A 3mg0V-1q5rH:
23.9
3mg0W-1q5rH:
23.3
3mg0V-1q5rH:
27.16
3mg0W-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H   1
GLN H  22
ALA H  27
GLY H  47
THR H  48
None
1.03A 3mg0V-1q5rH:
23.9
3mg0W-1q5rH:
23.3
3mg0V-1q5rH:
27.16
3mg0W-1q5rH:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
8 / 12 ALA H  20
THR H  21
ALA H  27
VAL H  31
ALA H  46
GLY H  47
ALA H  49
SER H 141
None
0.53A 3mg0Y-1q5rH:
13.4
3mg0Z-1q5rH:
22.2
3mg0Y-1q5rH:
27.59
3mg0Z-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 VAL H   4
ALA H  15
GLY H  16
ALA H 214
LEU H 150
None
1.23A 3rc0A-1q5rH:
undetectable
3rc0A-1q5rH:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 LEU H 109
ASP H 108
ALA H 117
TYR H 107
None
1.08A 3rodD-1q5rH:
undetectable
3rodD-1q5rH:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 5 LEU H  63
ALA H  80
THR H  37
PHE H  76
None
1.35A 3vasB-1q5rH:
undetectable
3vasB-1q5rH:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 8 GLY H 127
LEU H 104
VAL H 121
TYR H 130
None
0.88A 4fgzA-1q5rH:
undetectable
4fgzA-1q5rH:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 6 ILE H   3
THR H   1
VAL H 121
ASP H 124
None
0.86A 4iaqA-1q5rH:
0.5
4iaqA-1q5rH:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 ILE H   3
THR H   1
VAL H 121
ASP H 124
None
0.90A 4iarA-1q5rH:
undetectable
4iarA-1q5rH:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
3 / 3 VAL H 205
SER H 206
THR H 209
None
0.28A 4luhA-1q5rH:
undetectable
4luhA-1q5rH:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 4qvlK-1q5rH:
23.9
4qvlL-1q5rH:
22.5
4qvlK-1q5rH:
27.59
4qvlL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 4qvlY-1q5rH:
13.5
4qvlZ-1q5rH:
22.3
4qvlY-1q5rH:
27.59
4qvlZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.52A 4qvmK-1q5rH:
23.7
4qvmL-1q5rH:
22.3
4qvmK-1q5rH:
27.59
4qvmL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.52A 4qvmY-1q5rH:
13.4
4qvmZ-1q5rH:
22.1
4qvmY-1q5rH:
27.59
4qvmZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qvnK-1q5rH:
24.0
4qvnL-1q5rH:
22.5
4qvnK-1q5rH:
27.59
4qvnL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qvnY-1q5rH:
13.5
4qvnZ-1q5rH:
22.2
4qvnY-1q5rH:
27.59
4qvnZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.50A 4qvpK-1q5rH:
23.8
4qvpL-1q5rH:
22.2
4qvpK-1q5rH:
28.09
4qvpL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.50A 4qvpY-1q5rH:
13.5
4qvpZ-1q5rH:
22.2
4qvpY-1q5rH:
28.09
4qvpZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qvqK-1q5rH:
23.9
4qvqL-1q5rH:
22.4
4qvqK-1q5rH:
28.02
4qvqL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qvqY-1q5rH:
13.5
4qvqZ-1q5rH:
22.1
4qvqY-1q5rH:
28.02
4qvqZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.35A 4qvvH-1q5rH:
22.3
4qvvH-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.85A 4qvvH-1q5rH:
22.3
4qvvH-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.35A 4qvvV-1q5rH:
23.9
4qvvV-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.84A 4qvvV-1q5rH:
23.9
4qvvV-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.36A 4qvyH-1q5rH:
22.3
4qvyH-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.84A 4qvyH-1q5rH:
22.3
4qvyH-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
VAL H  31
GLY H  47
None
0.62A 4qvyK-1q5rH:
23.7
4qvyL-1q5rH:
22.4
4qvyK-1q5rH:
26.96
4qvyL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
VAL H  31
GLY H  47
None
0.62A 4qvyY-1q5rH:
13.4
4qvyZ-1q5rH:
22.1
4qvyY-1q5rH:
26.96
4qvyZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.79A 4qw1H-1q5rH:
22.3
4qw1I-1q5rH:
20.4
4qw1H-1q5rH:
26.88
4qw1I-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qw1K-1q5rH:
23.9
4qw1L-1q5rH:
22.4
4qw1K-1q5rH:
27.59
4qw1L-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.79A 4qw1V-1q5rH:
23.9
4qw1W-1q5rH:
23.3
4qw1V-1q5rH:
26.88
4qw1W-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.48A 4qw1Y-1q5rH:
17.7
4qw1Z-1q5rH:
22.2
4qw1Y-1q5rH:
27.59
4qw1Z-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 4qw3K-1q5rH:
23.7
4qw3L-1q5rH:
22.2
4qw3K-1q5rH:
27.59
4qw3L-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 4qw3Y-1q5rH:
17.5
4qw3Z-1q5rH:
21.9
4qw3Y-1q5rH:
27.59
4qw3Z-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
GLY H  47
None
1.13A 4qwuK-1q5rH:
23.3
4qwuL-1q5rH:
22.3
4qwuK-1q5rH:
27.59
4qwuL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 THR H   1
ALA H  20
THR H  21
ALA H  27
GLY H  47
None
1.12A 4qwuY-1q5rH:
17.5
4qwuZ-1q5rH:
22.3
4qwuY-1q5rH:
27.59
4qwuZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 ALA H  99
GLY H  92
ALA H  84
GLY H 127
TYR H 123
None
1.30A 4r29A-1q5rH:
undetectable
4r29A-1q5rH:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 ALA H  99
GLY H  92
ALA H  84
GLY H 127
TYR H 123
None
1.23A 4r29C-1q5rH:
undetectable
4r29C-1q5rH:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 THR H 196
LEU H  13
THR H 210
LEU H 213
None
0.87A 4z91F-1q5rH:
undetectable
4z91G-1q5rH:
undetectable
4z91H-1q5rH:
undetectable
4z91I-1q5rH:
undetectable
4z91J-1q5rH:
undetectable
4z91F-1q5rH:
19.78
4z91G-1q5rH:
19.78
4z91H-1q5rH:
19.78
4z91I-1q5rH:
19.78
4z91J-1q5rH:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 4 LEU H  83
MET H  86
VAL H  87
ASN H  90
None
1.34A 5b8iB-1q5rH:
0.3
5b8iB-1q5rH:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.49A 5bxnK-1q5rH:
23.9
5bxnL-1q5rH:
22.2
5bxnK-1q5rH:
27.59
5bxnL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.31A 5bxnV-1q5rH:
24.0
5bxnW-1q5rH:
23.4
5bxnV-1q5rH:
26.61
5bxnW-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.80A 5bxnV-1q5rH:
24.0
5bxnW-1q5rH:
23.4
5bxnV-1q5rH:
26.61
5bxnW-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.49A 5bxnY-1q5rH:
13.5
5bxnZ-1q5rH:
22.2
5bxnY-1q5rH:
27.59
5bxnZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 5d0xK-1q5rH:
23.8
5d0xL-1q5rH:
22.3
5d0xK-1q5rH:
23.23
5d0xL-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.34A 5d0xV-1q5rH:
23.9
5d0xV-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.76A 5d0xV-1q5rH:
23.9
5d0xV-1q5rH:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.51A 5d0xY-1q5rH:
13.5
5d0xZ-1q5rH:
22.1
5d0xY-1q5rH:
23.23
5d0xZ-1q5rH:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.44A 5l5fH-1q5rH:
22.3
5l5fI-1q5rH:
20.3
5l5fH-1q5rH:
26.88
5l5fI-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.46A 5l5fV-1q5rH:
23.9
5l5fW-1q5rH:
23.3
5l5fV-1q5rH:
26.88
5l5fW-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.39A 5l5zH-1q5rH:
22.3
5l5zI-1q5rH:
20.4
5l5zH-1q5rH:
26.88
5l5zI-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.64A 5l5zK-1q5rH:
23.7
5l5zL-1q5rH:
22.1
5l5zK-1q5rH:
28.38
5l5zL-1q5rH:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 THR H  21
GLN H  22
ALA H  46
GLY H  47
ALA H  49
None
0.40A 5l5zV-1q5rH:
23.8
5l5zW-1q5rH:
23.3
5l5zV-1q5rH:
26.88
5l5zW-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 9 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.64A 5l5zY-1q5rH:
23.7
5l5zZ-1q5rH:
22.1
5l5zY-1q5rH:
28.38
5l5zZ-1q5rH:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.50A 5l66H-1q5rH:
22.3
5l66I-1q5rH:
20.4
5l66H-1q5rH:
26.88
5l66I-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 12 GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.50A 5l66V-1q5rH:
23.9
5l66W-1q5rH:
23.3
5l66V-1q5rH:
26.88
5l66W-1q5rH:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  46
GLY H  47
ALA H  49
None
0.26A 5lf3H-1q5rH:
24.6
5lf3I-1q5rH:
23.0
5lf3H-1q5rH:
26.32
5lf3I-1q5rH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 10 ALA H  20
THR H  21
ALA H  46
GLY H  47
ALA H  49
None
0.30A 5lf3V-1q5rH:
24.5
5lf3W-1q5rH:
23.3
5lf3V-1q5rH:
26.32
5lf3W-1q5rH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  46
GLY H  47
ALA H  49
None
0.32A 5lf7H-1q5rH:
24.6
5lf7I-1q5rH:
23.4
5lf7H-1q5rH:
26.32
5lf7I-1q5rH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
VAL H  31
GLY H  47
ALA H  49
None
0.29A 5lf7K-1q5rH:
24.6
5lf7L-1q5rH:
23.2
5lf7K-1q5rH:
29.13
5lf7L-1q5rH:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  46
GLY H  47
ALA H  49
None
0.30A 5lf7V-1q5rH:
24.5
5lf7W-1q5rH:
23.4
5lf7V-1q5rH:
26.32
5lf7W-1q5rH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
VAL H  31
GLY H  47
ALA H  49
None
0.30A 5lf7Y-1q5rH:
24.6
5lf7Z-1q5rH:
23.2
5lf7Y-1q5rH:
29.13
5lf7Z-1q5rH:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 LEU H  13
GLY H  11
GLY H 118
ALA H 163
None
0.66A 5o96C-1q5rH:
undetectable
5o96C-1q5rH:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
4 / 7 SER H 170
LEU H 150
ALA H 138
ILE H 120
None
0.92A 5te8C-1q5rH:
0.8
5te8C-1q5rH:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 12 GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.48A 6hwdH-1q5rH:
22.3
6hwdI-1q5rH:
20.4
6hwdH-1q5rH:
19.48
6hwdI-1q5rH:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.46A 6hwdK-1q5rH:
23.9
6hwdL-1q5rH:
22.5
6hwdK-1q5rH:
17.47
6hwdL-1q5rH:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
6 / 11 GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
None
0.48A 6hwdV-1q5rH:
23.9
6hwdV-1q5rH:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1q5r PROTEASOME BETA-TYPE
SUBUNIT 1

(Rhodococcus
erythropolis)
5 / 11 ALA H  20
THR H  21
ALA H  27
GLY H  47
ALA H  49
None
0.46A 6hwdY-1q5rH:
17.6
6hwdZ-1q5rH:
22.3
6hwdY-1q5rH:
17.47
6hwdZ-1q5rH:
14.81