SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 1q5z SIPA
(Salmonella
enterica) 		5 / 12 LEU A 642
PHE A 545
GLN A 624
LEU A 623
ARG A 627
 None
 1.35A 1u72A-1q5zA:
undetectable		 1u72A-1q5zA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 1q5z SIPA
(Salmonella
enterica) 		4 / 8 ILE A 609
HIS A 612
LEU A 649
ARG A 571
 None
 0.98A 2vdbA-1q5zA:
0.0		 2vdbA-1q5zA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 1q5z SIPA
(Salmonella
enterica) 		4 / 7 ILE A 609
LEU A 546
THR A 638
THR A 527
 None
 1.28A 3nxuA-1q5zA:
undetectable		 3nxuA-1q5zA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 1q5z SIPA
(Salmonella
enterica) 		5 / 12 LEU A 646
LEU A 642
LEU A 575
VAL A 548
MET A 602
 None
 1.27A 4olmA-1q5zA:
undetectable		 4olmA-1q5zA:
21.62