SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_B_H3PB552_1 (GLUTAMATE DEHYDROGENASE)	1q67	DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P (Saccharomyces cerevisiae)	3 / 3	TYR A 30 TYR A 68 ILE A 34	None	0.75A	3eteA-1q67A: undetectable 3eteB-1q67A: undetectable	3eteA-1q67A: 19.35 3eteB-1q67A: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HGX_A_SALA102_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	1q67	DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P (Saccharomyces cerevisiae)	4 / 7	VAL A 186 ILE A 218 TYR A 215 ILE A 214	None	0.89A	3hgxA-1q67A: undetectable	3hgxA-1q67A: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XV2_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	1q67	DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P (Saccharomyces cerevisiae)	4 / 4	GLY A 63 LEU A 37 PHE A 24 ILE A 27	None	0.70A	4xv2A-1q67A: undetectable	4xv2A-1q67A: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FA8_A_SAMA301_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE)	1q67	DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P (Saccharomyces cerevisiae)	5 / 12	GLY A 141 ILE A 218 ARG A 70 PHE A 153 LEU A 196	None	1.05A	5fa8A-1q67A: undetectable	5fa8A-1q67A: 21.01

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ETE_B_H3PB552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","1q67","DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P","Saccharomyces cerevisiae",3,"TYR A  30;TYR A  68;ILE A  34","None","0.75A","3eteA-1q67A:undetectable;3eteB-1q67A:undetectable","3eteA-1q67A:19.35;3eteB-1q67A:19.35"],["3HGX_A_SALA102_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB","1q67","DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P","Saccharomyces cerevisiae",4,"VAL A 186;ILE A 218;TYR A 215;ILE A 214","None","0.89A","3hgxA-1q67A:undetectable","3hgxA-1q67A:16.88"],["4XV2_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","1q67","DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P","Saccharomyces cerevisiae",4,"GLY A  63;LEU A  37;PHE A  24;ILE A  27","None","0.70A","4xv2A-1q67A:undetectable","4xv2A-1q67A:20.38"],["5FA8_A_SAMA301_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE, PUTATIVE","1q67","DECAPPING PROTEIN INVOLVED IN MRNA DEGRADATION-DCP1P","Saccharomyces cerevisiae",5,"GLY A 141;ILE A 218;ARG A  70;PHE A 153;LEU A 196","None","1.05A","5fa8A-1q67A:undetectable","5fa8A-1q67A:21.01"]]