SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		6 / 8 LEU A   2
ALA A  18
ILE A  19
GLY A  30
HIS A  48
PHE A 106
 None
 0.71A 1sv9A-1q6vA:
25.2		 1sv9A-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 None
 0.22A 1th6A-1q6vA:
25.3		 1th6A-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		4 / 7 GLY A  30
HIS A  48
TYR A  52
PRO A  68
 None
 0.24A 2armA-1q6vA:
25.3		 2armA-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		6 / 10 LEU A   2
ALA A  18
ILE A  19
GLY A  30
HIS A  48
PHE A 106
 None
 0.71A 2b17A-1q6vA:
25.2		 2b17A-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 10 LEU A   2
ALA A  18
ILE A  19
GLY A  30
LYS A  69
 None
 1.22A 2b17A-1q6vA:
25.2		 2b17A-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 6 LEU A   2
ALA A  18
HIS A  48
TYR A  52
LYS A  69
 None
 0.73A 2dpzA-1q6vA:
25.7		 2dpzA-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 5 LEU A   2
ILE A  19
SER A  23
GLY A  30
HIS A  48
 None
 0.74A 2otfA-1q6vA:
25.4		 2otfA-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		4 / 5 LEU A   2
ALA A  18
ILE A  19
SER A  23
 None
 0.80A 2othA-1q6vA:
24.9		 2othA-1q6vA:
95.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 9 LYS A  16
TYR A 113
TYR A 117
PRO A 121
PHE A 124
 None
 0.95A 3bjwG-1q6vA:
22.0		 3bjwG-1q6vA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 9 LYS A  16
TYR A 113
TYR A 117
PRO A 121
PHE A 124
 None
 0.88A 3bjwA-1q6vA:
21.9		 3bjwA-1q6vA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_1
(PHOSPHOLIPASE A2)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 9 LYS A  16
TYR A 113
TYR A 117
PRO A 121
PHE A 124
 None
 0.91A 3bjwC-1q6vA:
22.0		 3bjwC-1q6vA:
65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		4 / 5 HIS A  48
TYR A  52
PRO A  68
LYS A  69
 None
 0.34A 3h1xA-1q6vA:
25.2		 3h1xA-1q6vA:
95.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		3 / 3 GLU A 129
GLY A  35
THR A  36
 None
 0.45A 3iazA-1q6vA:
undetectable		 3iazA-1q6vA:
15.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		4 / 5 PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
 0.65A 3r0lD-1q6vA:
21.9		 3r0lD-1q6vA:
58.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA
(Daboia
russelii) 		5 / 9 VAL A  47
ALA A 102
PHE A 106
TYR A 113
TYR A  25
 None
 1.47A 4lb2B-1q6vA:
2.1		 4lb2B-1q6vA:
11.19