SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 113
ALA A 115
ALA A 149
LEU A 147
ILE A  98
 None
 1.08A 2h79A-1q6wA:
0.0		 2h79A-1q6wA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A  16
SER A  91
VAL A  92
 None
 0.81A 3eeoA-1q6wA:
undetectable		 3eeoA-1q6wA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 113
ALA A 115
ALA A 149
LEU A 147
ILE A  98
 None
 1.05A 3gwsX-1q6wA:
0.0		 3gwsX-1q6wA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 8 VAL A  71
LEU A  72
ILE A 113
VAL A 138
LEU A 136
 None
 1.24A 3kp6A-1q6wA:
undetectable
3kp6B-1q6wA:
undetectable		 3kp6A-1q6wA:
21.59
3kp6B-1q6wA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 7 LEU A  84
ASP A  80
VAL A 132
ILE A  83
 None
 0.75A 3wsjB-1q6wA:
undetectable		 3wsjB-1q6wA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.07A 4rrwA-1q6wA:
undetectable		 4rrwA-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.07A 4rrwB-1q6wA:
undetectable		 4rrwB-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.09A 4rrwC-1q6wA:
undetectable		 4rrwC-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.07A 4rrzA-1q6wA:
undetectable		 4rrzA-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.07A 4rrzB-1q6wA:
undetectable		 4rrzB-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 138
LEU A 136
SER A 116
VAL A  79
GLY A  77
 None
 1.09A 4rrzC-1q6wA:
undetectable		 4rrzC-1q6wA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 MET A  78
ILE A  74
LEU A  27
LEU A  70
THR A  34
 None
 1.21A 5bykA-1q6wA:
0.0		 5bykA-1q6wA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 MET A  78
ILE A  74
LEU A  27
LEU A  70
THR A  38
 None
 1.28A 5bykA-1q6wA:
0.0		 5bykA-1q6wA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 8 VAL A  31
ILE A  74
ALA A  75
HIS A  50
VAL A 107
 None
 1.39A 5l94A-1q6wA:
undetectable		 5l94A-1q6wA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		6 / 12 MET A  78
ILE A  74
LEU A  27
ASP A  35
LEU A  70
THR A  38
 None
 1.34A 6b54A-1q6wA:
undetectable		 6b54A-1q6wA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 MET A  78
ILE A  74
LEU A  27
LEU A  70
THR A  34
 None
 1.12A 6b54A-1q6wA:
undetectable		 6b54A-1q6wA:
24.80