SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 HIS A  80
GLY B 347
GLY A 151
ASP A  82
 ZN  A1002 ( 3.2A)
None
None
None
 0.85A 1aegA-1q7lA:
undetectable		 1aegA-1q7lA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.87A 1v7zA-1q7lA:
undetectable		 1v7zA-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.87A 1v7zB-1q7lA:
undetectable		 1v7zB-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.88A 1v7zC-1q7lA:
undetectable		 1v7zC-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.88A 1v7zD-1q7lA:
undetectable		 1v7zD-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.87A 1v7zE-1q7lA:
undetectable		 1v7zE-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.87A 1v7zF-1q7lA:
undetectable		 1v7zF-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		5 / 12 LEU B 398
ILE B 390
VAL B 330
ALA B 397
LEU A  77
 None
 1.19A 2japA-1q7lB:
undetectable		 2japA-1q7lB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		5 / 12 LEU B 398
ILE B 390
VAL B 330
ALA B 397
LEU A  77
 None
 1.13A 2japB-1q7lB:
undetectable		 2japB-1q7lB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		5 / 12 LEU B 398
ILE B 390
VAL B 330
ALA B 397
LEU A  77
 None
 1.19A 2japC-1q7lB:
undetectable		 2japC-1q7lB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		5 / 12 LEU B 398
ILE B 390
VAL B 330
ALA B 397
LEU A  77
 None
 1.15A 2japD-1q7lB:
undetectable		 2japD-1q7lB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.91A 3a6jA-1q7lA:
undetectable		 3a6jA-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 7 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.91A 3a6jB-1q7lA:
undetectable		 3a6jB-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.91A 3a6jC-1q7lA:
undetectable		 3a6jC-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.92A 3a6jE-1q7lA:
undetectable		 3a6jE-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 GLU A 175
HIS A  80
ASP A 113
GLU A 148
 ZN  A1002 ( 1.9A)
ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1001 (-1.9A)
 0.91A 3a6jF-1q7lA:
undetectable		 3a6jF-1q7lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 6 HIS B 373
GLU A 175
PHE A 187
PRO B 344
 ZN  A1001 ( 3.2A)
ZN  A1002 ( 1.9A)
None
None
 1.29A 3gclA-1q7lB:
undetectable		 3gclA-1q7lB:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 8 PHE A 158
VAL A  54
VAL A 159
GLY A 154
 None
 0.91A 3hjoA-1q7lA:
undetectable		 3hjoA-1q7lA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 7 PHE A 158
VAL A  54
VAL A 159
GLY A 154
 None
 0.94A 3kmoB-1q7lA:
undetectable		 3kmoB-1q7lA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 7 ILE B 390
PHE B 362
LEU B 336
THR A 181
 None
 0.99A 4mmcA-1q7lB:
undetectable		 4mmcA-1q7lB:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		4 / 6 ASP A 146
GLU A  53
VAL A  35
ALA A  34
 None
 0.97A 4nkxA-1q7lA:
undetectable		 4nkxA-1q7lA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 1q7l AMINOACYLASE-1
(Homo
sapiens) 		6 / 11 HIS A  80
ASP A 113
GLU A 147
GLU A 148
GLU A 175
HIS B 373
 ZN  A1002 ( 3.2A)
ZN  A1002 (-2.5A)
ZN  A1002 ( 3.8A)
ZN  A1001 (-1.9A)
ZN  A1002 ( 1.9A)
ZN  A1001 ( 3.2A)
 0.22A 4pqaA-1q7lA:
17.1		 4pqaA-1q7lA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1q7l AMINOACYLASE-1
AMINOACYLASE-1
(Homo
sapiens;
Homo
sapiens) 		5 / 12 HIS A  80
GLU A 147
GLY B 347
GLY A 176
LEU B 372
 ZN  A1002 ( 3.2A)
ZN  A1002 ( 3.8A)
None
None
None
 1.40A 4uinH-1q7lA:
undetectable
4uinL-1q7lA:
undetectable		 4uinH-1q7lA:
19.50
4uinL-1q7lA:
20.98