SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q7r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		5 / 11 GLU A  20
VAL A  16
ILE A  19
LEU A  35
LEU A  41
 None
 1.36A 1mrqA-1q7rA:
undetectable		 1mrqA-1q7rA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		4 / 7 PHE A  75
TYR A 181
ASN A 184
VAL A 124
 None
 1.18A 1wu8A-1q7rA:
undetectable
1wu8C-1q7rA:
undetectable		 1wu8A-1q7rA:
22.22
1wu8C-1q7rA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		5 / 8 GLY A  80
GLY A  45
GLY A  46
ALA A  79
HIS A 169
 None
 0.95A 1yajC-1q7rA:
undetectable		 1yajC-1q7rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		4 / 6 MET A  51
LEU A  54
GLN A  34
TYR A  58
 None
 1.18A 3vkxA-1q7rA:
0.0		 3vkxA-1q7rA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		3 / 3 LEU A  84
MET A  99
ASP A  39
 None
 0.81A 4j7xB-1q7rA:
2.8		 4j7xB-1q7rA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZP0_A_DXCA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		5 / 10 MET A  74
LEU A  43
PRO A  63
LEU A  96
GLY A  46
 None
 1.34A 4zp0A-1q7rA:
undetectable		 4zp0A-1q7rA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 1q7r PREDICTED
AMIDOTRANSFERASE
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  43
MET A  99
ILE A   3
LEU A 164
 None
 1.35A 5nfpA-1q7rA:
0.0		 5nfpA-1q7rA:
21.28