SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN
(Hediste
diversicolor) 		3 / 3 PHE A 119
LEU A 145
SER A 133
 None
 0.72A 1e7aA-1q80A:
0.8		 1e7aA-1q80A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN
(Hediste
diversicolor) 		4 / 8 SER A 133
PHE A 150
VAL A 103
SER A  52
 None
 1.12A 1kb9A-1q80A:
0.0
1kb9C-1q80A:
0.4
1kb9D-1q80A:
0.0
1kb9E-1q80A:
undetectable		 1kb9A-1q80A:
19.15
1kb9C-1q80A:
18.68
1kb9D-1q80A:
20.31
1kb9E-1q80A:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN
(Hediste
diversicolor) 		5 / 9 ILE A  15
PRO A  95
PHE A 158
LEU A  96
PHE A 150
 None
 1.32A 4qopA-1q80A:
0.0		 4qopA-1q80A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN
(Hediste
diversicolor) 		5 / 9 ILE A  15
PRO A  95
PHE A 158
LEU A  96
PHE A 150
 None
 1.32A 4qopB-1q80A:
0.0		 4qopB-1q80A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1q80 SARCOPLASMIC
CALCIUM-BINDING
PROTEIN
(Hediste
diversicolor) 		4 / 6 THR A 165
ASN A 166
ILE A 137
GLU A 149
 None
 1.15A 5uigA-1q80A:
undetectable		 5uigA-1q80A:
16.48