SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 1q87 39 KDA INITIATOR
BINDING PROTEIN
(Trichomonas
vaginalis) 		3 / 3 TRP A 275
LYS A 226
PRO A 259
 None
 1.29A 2dqyB-1q87A:
1.7		 2dqyB-1q87A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 1q87 39 KDA INITIATOR
BINDING PROTEIN
(Trichomonas
vaginalis) 		4 / 7 PHE A 231
LEU A 255
PHE A 276
ILE A 295
 None
 0.95A 2v0mC-1q87A:
undetectable		 2v0mC-1q87A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1q87 39 KDA INITIATOR
BINDING PROTEIN
(Trichomonas
vaginalis) 		5 / 12 PHE A 276
ILE A 295
THR A 236
TYR A 307
LEU A 308
 None
 1.47A 4qztC-1q87A:
undetectable		 4qztC-1q87A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 1q87 39 KDA INITIATOR
BINDING PROTEIN
(Trichomonas
vaginalis) 		5 / 12 PHE A 276
ALA A 212
ALA A 209
LEU A 245
THR A 236
 None
 1.16A 5tl8A-1q87A:
undetectable		 5tl8A-1q87A:
18.24