SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XO7_A_ASDA402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	1q8c	HYPOTHETICAL PROTEIN MG027 (Mycoplasma genitalium)	4 / 7	VAL A 22 ILE A 25 LEU A 147 LEU A 110	None	1.01A	4xo7A-1q8cA: undetectable	4xo7A-1q8cA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FUK_A_SNPA1236_1 (MROUPO)	1q8c	HYPOTHETICAL PROTEIN MG027 (Mycoplasma genitalium)	4 / 7	ILE A 75 ILE A 68 ILE A 25 LEU A 32	None IOD A 154 ( 4.5A) None IOD A 154 ( 4.9A)	0.67A	5fukA-1q8cA: undetectable 5fukB-1q8cA: undetectable	5fukA-1q8cA: 21.52 5fukB-1q8cA: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TDZ_A_ADNA905_1 (ATP-CITRATE SYNTHASE)	1q8c	HYPOTHETICAL PROTEIN MG027 (Mycoplasma genitalium)	4 / 6	ARG A 14 THR A 118 ASP A 119 LEU A 122	IOD A 153 ( 4.6A) None None None	1.02A	5tdzA-1q8cA: undetectable	5tdzA-1q8cA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TDZ_A_ADNA905_1 (ATP-CITRATE SYNTHASE)	1q8c	HYPOTHETICAL PROTEIN MG027 (Mycoplasma genitalium)	4 / 6	ARG A 14 THR A 118 ASP A 119 LEU A 123	IOD A 153 ( 4.6A) None None None	1.09A	5tdzA-1q8cA: undetectable	5tdzA-1q8cA: 19.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4XO7_A_ASDA402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","1q8c","HYPOTHETICAL PROTEIN MG027","Mycoplasma genitalium",4,"VAL A  22;ILE A  25;LEU A 147;LEU A 110","None","1.01A","4xo7A-1q8cA:undetectable","4xo7A-1q8cA:20.45"],["5FUK_A_SNPA1236_1","MROUPO;MROUPO","1q8c","HYPOTHETICAL PROTEIN MG027","Mycoplasma genitalium",4,"ILE A  75;ILE A  68;ILE A  25;LEU A  32","None;IOD A 154 ( 4.5A);None;IOD A 154 ( 4.9A)","0.67A","5fukA-1q8cA:undetectable;5fukB-1q8cA:undetectable","5fukA-1q8cA:21.52;5fukB-1q8cA:21.52"],["5TDZ_A_ADNA905_1","ATP-CITRATE SYNTHASE","1q8c","HYPOTHETICAL PROTEIN MG027","Mycoplasma genitalium",4,"ARG A  14;THR A 118;ASP A 119;LEU A 122","IOD A 153 ( 4.6A);None;None;None","1.02A","5tdzA-1q8cA:undetectable","5tdzA-1q8cA:19.30"],["5TDZ_A_ADNA905_1","ATP-CITRATE SYNTHASE","1q8c","HYPOTHETICAL PROTEIN MG027","Mycoplasma genitalium",4,"ARG A  14;THR A 118;ASP A 119;LEU A 123","IOD A 153 ( 4.6A);None;None;None","1.09A","5tdzA-1q8cA:undetectable","5tdzA-1q8cA:19.30"]]