SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		4 / 8 SER A  62
ILE A  54
PHE A  51
VAL A 133
 None
 0.97A 1kb9A-1q98A:
undetectable
1kb9C-1q98A:
undetectable
1kb9D-1q98A:
undetectable
1kb9E-1q98A:
undetectable		 1kb9A-1q98A:
20.79
1kb9C-1q98A:
19.84
1kb9D-1q98A:
20.72
1kb9E-1q98A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		3 / 3 PHE A  26
LEU A  48
LEU A 136
 None
 0.47A 1mx1E-1q98A:
undetectable		 1mx1E-1q98A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		5 / 11 ILE A 134
LYS A  46
LEU A  48
VAL A 118
PHE A  26
 None
 1.45A 1tw4A-1q98A:
0.0		 1tw4A-1q98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		5 / 12 LEU A 116
ALA A 132
ILE A 151
ILE A  54
VAL A 118
 None
 1.00A 2nnkA-1q98A:
undetectable		 2nnkA-1q98A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		5 / 12 PHE A  66
ILE A  77
PHE A  41
ALA A  70
THR A  76
 None
 1.38A 3ndiA-1q98A:
undetectable		 3ndiA-1q98A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1q98 THIOL PEROXIDASE
(Haemophilus
influenzae) 		3 / 3 LEU A 147
LEU A 136
ASN A  49
 None
 0.64A 4otwA-1q98A:
undetectable		 4otwA-1q98A:
19.88