SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1q9c SON OF SEVENLESS
PROTEIN
(Homo
sapiens) 		5 / 10 VAL A  30
TYR A  47
VAL A  48
ILE A 137
LEU A 142
 None
 1.03A 1fe2A-1q9cA:
undetectable		 1fe2A-1q9cA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1q9c SON OF SEVENLESS
PROTEIN
(Homo
sapiens) 		5 / 8 VAL A  30
TYR A  47
VAL A  48
ILE A 137
LEU A 142
 None
 1.09A 1igxA-1q9cA:
1.0		 1igxA-1q9cA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1q9c SON OF SEVENLESS
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 141
GLU A 135
LEU A 105
LEU A  45
 None
 1.05A 1mt1B-1q9cA:
undetectable
1mt1C-1q9cA:
undetectable		 1mt1B-1q9cA:
21.47
1mt1C-1q9cA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1q9c SON OF SEVENLESS
PROTEIN
(Homo
sapiens) 		4 / 8 TYR A 129
ILE A  87
LEU A  59
PHE A  78
 None
 1.05A 3rqwI-1q9cA:
undetectable
3rqwJ-1q9cA:
undetectable		 3rqwI-1q9cA:
21.56
3rqwJ-1q9cA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 1q9c SON OF SEVENLESS
PROTEIN
(Homo
sapiens) 		4 / 5 GLY A  21
ARG A  20
GLU A  50
PHE A  11
 None
 1.17A 4r82A-1q9cA:
undetectable
4r82B-1q9cA:
undetectable		 4r82A-1q9cA:
22.27
4r82B-1q9cA:
22.27