SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1q9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		12 / 12 ALA A 140
TYR A 142
TYR A 168
ASP A 170
SER A 171
GLN A 172
GLU A 209
ASP A 211
GLU A 214
THR A 243
ARG A 248
ASP A 373
 None
 0.28A 1dy4A-1q9hA:
64.4		 1dy4A-1q9hA:
66.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 5 HIS A 225
TRP A 371
ALA A 376
TRP A 380
 None
 0.29A 1dy4A-1q9hA:
64.4		 1dy4A-1q9hA:
66.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 5 THR A   5
LEU A  73
GLY A  75
TYR A 164
 None
PCA  A   1 ( 4.5A)
None
None
 1.29A 1gtiF-1q9hA:
undetectable		 1gtiF-1q9hA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 12 ASN A 121
GLY A 298
MET A 360
LEU A 353
ILE A 430
 None
None
None
None
NAG  A 440 ( 4.8A)
 1.39A 1p93B-1q9hA:
undetectable		 1p93B-1q9hA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLU A 214
ASN A 138
TRP A 380
 None
 1.25A 1r15D-1q9hA:
undetectable		 1r15D-1q9hA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLU A 214
ASN A 138
TRP A 380
 None
 1.24A 1r15E-1q9hA:
undetectable		 1r15E-1q9hA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLU A 214
ASN A 138
TRP A 380
 None
 1.24A 1r15F-1q9hA:
undetectable		 1r15F-1q9hA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 LEU A  34
TYR A  82
GLY A  80
 None
 0.63A 2ocuA-1q9hA:
undetectable		 2ocuA-1q9hA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLY A 165
ARG A  39
TYR A 106
 None
 0.80A 2opxA-1q9hA:
undetectable		 2opxA-1q9hA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 12 SER A 319
GLY A 266
PHE A 260
GLN A 337
GLY A 395
 None
 1.04A 2pkkA-1q9hA:
undetectable		 2pkkA-1q9hA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 8 THR A 113
GLN A 115
ILE A 116
ASP A 110
 None
 1.12A 2xytE-1q9hA:
0.1		 2xytE-1q9hA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 8 THR A 113
GLN A 115
ILE A 116
ASP A 110
 None
 1.06A 2xytH-1q9hA:
0.0		 2xytH-1q9hA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 7 THR A 113
GLN A 115
ILE A 116
ASP A 110
 None
 1.11A 2xytI-1q9hA:
undetectable		 2xytI-1q9hA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 12 SER A 112
ALA A 160
GLY A 165
THR A 166
LEU A 105
 None
PCA  A   1 ( 3.7A)
None
None
None
 1.21A 2zifB-1q9hA:
undetectable		 2zifB-1q9hA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 LEU A 300
GLU A 302
ILE A 329
 None
 0.61A 3czhA-1q9hA:
undetectable		 3czhA-1q9hA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 TYR A 155
GLY A 151
ASP A 149
 None
 0.59A 3ou6C-1q9hA:
undetectable		 3ou6C-1q9hA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 8 ASP A 211
GLY A 257
GLU A 214
ARG A 248
 None
 0.98A 3s3nA-1q9hA:
undetectable		 3s3nA-1q9hA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 11 GLY A 167
ALA A 162
GLY A 150
MET A 146
VAL A 365
 None
 1.32A 4c5lA-1q9hA:
undetectable		 4c5lA-1q9hA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 10 GLY A 167
ALA A 162
GLY A 150
MET A 146
VAL A 365
 None
 1.30A 4c5lD-1q9hA:
undetectable		 4c5lD-1q9hA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLN A  28
THR A  27
THR A  26
 None
 0.82A 4fu9A-1q9hA:
0.0		 4fu9A-1q9hA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 GLN A  28
THR A  27
THR A  26
 None
 0.82A 4fufA-1q9hA:
0.0		 4fufA-1q9hA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		9 / 9 ASN A 138
ALA A 140
TYR A 142
TYR A 168
ASP A 170
GLU A 209
ASP A 211
GLU A 214
TRP A 371
 None
 0.45A 4ipmA-1q9hA:
61.2		 4ipmA-1q9hA:
55.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 5 TYR A 168
SER A 369
ASP A 211
ASP A 259
 None
 1.25A 4qtuB-1q9hA:
undetectable		 4qtuB-1q9hA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 SER A 219
ALA A 221
VAL A 222
 None
 0.53A 4x1iA-1q9hA:
undetectable		 4x1iA-1q9hA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		3 / 3 SER A 219
ALA A 221
VAL A 222
 None
 0.58A 4x20C-1q9hA:
undetectable		 4x20C-1q9hA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		5 / 12 ILE A 425
VAL A 285
VAL A 286
LEU A 366
THR A 433
 None
 1.27A 5bykA-1q9hA:
undetectable		 5bykA-1q9hA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 1q9h CELLOBIOHYDROLASE I
CATALYTIC DOMAIN
(Rasamsonia
emersonii) 		4 / 8 GLY A 204
TRP A 189
ASP A 202
ASP A 239
 None
 1.01A 5vlmH-1q9hA:
undetectable		 5vlmH-1q9hA:
17.62