SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		5 / 11 ILE A 243
ASP A 181
GLY A 182
PHE A 185
VAL A 172
 None
 1.47A 1axwB-1qagA:
undetectable		 1axwB-1qagA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		4 / 5 ARG A  86
ALA A  89
ASP A 117
GLY A 112
 None
 1.19A 1e7bA-1qagA:
undetectable		 1e7bA-1qagA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		5 / 12 GLY A  63
ALA A  89
LEU A  90
VAL A  96
LEU A 126
 None
 1.05A 2nyuB-1qagA:
undetectable		 2nyuB-1qagA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		5 / 12 ILE A 110
ILE A 115
GLY A  63
LEU A  69
LEU A 100
 None
 1.06A 3em0B-1qagA:
undetectable		 3em0B-1qagA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		5 / 10 ARG A  64
ILE A 110
GLY A 111
GLY A 112
LEU A  90
 None
 1.02A 3em4V-1qagA:
undetectable		 3em4V-1qagA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		5 / 12 LEU A  73
LEU A  70
LEU A  66
ILE A  41
ILE A 130
 None
 0.95A 4a7aB-1qagA:
undetectable		 4a7aB-1qagA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		3 / 3 THR A 150
ASN A 151
SER A 152
 None
 0.71A 4tvtA-1qagA:
undetectable		 4tvtA-1qagA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1qag UTROPHIN ACTIN
BINDING REGION
(Homo
sapiens) 		4 / 7 ASN A  92
ALA A  89
LYS A  61
LEU A  67
 None
 1.04A 6ci6A-1qagA:
undetectable		 6ci6A-1qagA:
17.26