SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qah'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A  37
GLU A  53
ARG A 119
LEU A  45
LEU A  82
 None
 0.96A 1jg3A-1qahA:
undetectable		 1jg3A-1qahA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A  37
GLU A  53
ARG A 119
LEU A  45
LEU A  82
 None
 0.96A 1jg3B-1qahA:
undetectable		 1jg3B-1qahA:
22.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 7 TYR A  20
ILE A  36
PRO A 115
GLU A 121
 None
 0.22A 1oniA-1qahA:
25.7
1oniB-1qahA:
26.5		 1oniA-1qahA:
87.50
1oniB-1qahA:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 6 TYR A  20
ILE A  36
PRO A 115
GLU A 121
 None
 0.16A 1oniB-1qahA:
26.5
1oniC-1qahA:
26.5		 1oniB-1qahA:
87.50
1oniC-1qahA:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 6 TYR A  20
ILE A  36
PRO A 115
GLU A 121
 None
 0.29A 1oniA-1qahA:
25.7
1oniC-1qahA:
26.5		 1oniA-1qahA:
87.50
1oniC-1qahA:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 7 ILE A  17
TYR A  20
ILE A  36
GLU A 121
 None
 0.55A 1oniD-1qahA:
26.1
1oniF-1qahA:
26.3		 1oniD-1qahA:
87.50
1oniF-1qahA:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 7 TYR A  20
ILE A  36
PRO A 115
GLU A 121
 None
 0.37A 1oniD-1qahA:
26.1
1oniE-1qahA:
26.2		 1oniD-1qahA:
87.50
1oniE-1qahA:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 7 TYR A  20
ILE A  36
PRO A 115
GLU A 121
 None
 0.21A 1oniG-1qahA:
26.4
1oniI-1qahA:
25.9		 1oniG-1qahA:
87.50
1oniI-1qahA:
87.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.85A 1sdvB-1qahA:
undetectable		 1sdvB-1qahA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.88A 2f8gB-1qahA:
undetectable		 2f8gB-1qahA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.88A 2o4kB-1qahA:
undetectable		 2o4kB-1qahA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		6 / 12 GLY A  69
ALA A  68
VAL A  32
ILE A  64
GLY A  62
ILE A  30
 None
 1.30A 2o4lB-1qahA:
undetectable		 2o4lB-1qahA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.79A 2o4sB-1qahA:
undetectable		 2o4sB-1qahA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.89A 2r5pB-1qahA:
undetectable		 2r5pB-1qahA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.76A 2r5qB-1qahA:
undetectable		 2r5qB-1qahA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 10 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.76A 2r5qD-1qahA:
undetectable		 2r5qD-1qahA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		4 / 7 ILE A 122
ALA A 124
VAL A  32
GLY A  62
 None
 0.76A 2xrzB-1qahA:
undetectable		 2xrzB-1qahA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.87A 3bvbA-1qahA:
undetectable		 3bvbA-1qahA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.95A 3em4A-1qahA:
undetectable		 3em4A-1qahA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  69
ALA A  68
ILE A  64
GLY A  62
ILE A  30
 None
 0.86A 3nu5A-1qahA:
undetectable		 3nu5A-1qahA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 10 ASP A  71
CYH A  70
GLY A  69
ALA A  68
THR A  10
 None
 1.18A 3ucjB-1qahA:
undetectable		 3ucjB-1qahA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 VAL A  80
LEU A  82
VAL A  50
ALA A  54
LEU A  58
 None
 1.13A 4rrwA-1qahA:
undetectable		 4rrwA-1qahA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 VAL A  80
LEU A  82
VAL A  50
ALA A  54
LEU A  58
 None
 1.14A 4rrwB-1qahA:
undetectable		 4rrwB-1qahA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 VAL A  80
LEU A  82
VAL A  50
ALA A  54
LEU A  58
 None
 1.13A 4rrzA-1qahA:
undetectable		 4rrzA-1qahA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		5 / 12 VAL A  80
LEU A  82
VAL A  50
ALA A  54
LEU A  58
 None
 1.14A 4rrzB-1qahA:
undetectable		 4rrzB-1qahA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		3 / 3 GLU A  93
TYR A  95
ARG A 106
 None
 0.76A 5uunA-1qahA:
undetectable		 5uunA-1qahA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1qah PERCHLORIC ACID
SOLUBLE PROTEIN
(Rattus
norvegicus) 		3 / 3 GLU A  93
TYR A  95
ARG A 106
 None
 0.83A 5uunB-1qahA:
undetectable		 5uunB-1qahA:
20.66