SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qap'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 TRP A  72
ALA A  24
VAL A  26
 None
 0.95A 1c4dA-1qapA:
undetectable
1c4dB-1qapA:
undetectable		 1c4dA-1qapA:
7.69
1c4dB-1qapA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 6 VAL A 130
GLY A 129
ALA A 165
LEU A 162
 None
 0.81A 1e7bB-1qapA:
undetectable		 1e7bB-1qapA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
VAL A 166
TYR A 137
GLY A 169
LEU A 141
 None
 1.39A 1fk9A-1qapA:
0.6		 1fk9A-1qapA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.95A 1hsgA-1qapA:
undetectable		 1hsgA-1qapA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.87A 1hxbB-1qapA:
undetectable		 1hxbB-1qapA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 THR A 126
LEU A 127
LEU A 167
 None
 0.62A 1mz9C-1qapA:
undetectable		 1mz9C-1qapA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 ILE A  78
LEU A 106
VAL A  85
GLU A  74
LEU A  87
 None
 1.34A 2bxfB-1qapA:
undetectable		 2bxfB-1qapA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 9 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.96A 2o4pB-1qapA:
undetectable		 2o4pB-1qapA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 6 ILE A 232
LEU A 234
LEU A 225
ASP A 222
 None
 1.07A 2rlfA-1qapA:
undetectable
2rlfD-1qapA:
undetectable		 2rlfA-1qapA:
9.25
2rlfD-1qapA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.99A 3em3B-1qapA:
undetectable		 3em3B-1qapA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.94A 3jvyB-1qapA:
undetectable		 3jvyB-1qapA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.92A 3k4vC-1qapA:
undetectable		 3k4vC-1qapA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 6 VAL A  59
LEU A  30
ILE A  22
ALA A 120
LEU A 121
 None
 1.18A 3kk6B-1qapA:
undetectable		 3kk6B-1qapA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.92A 3ndtD-1qapA:
undetectable		 3ndtD-1qapA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 1.04A 3oxwD-1qapA:
undetectable		 3oxwD-1qapA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 155
THR A 154
ALA A 161
ALA A 165
LEU A 127
 None
 1.17A 3p5nA-1qapA:
1.4		 3p5nA-1qapA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
VAL A 166
TYR A 137
GLY A 169
LEU A 141
 None
 1.38A 3qipA-1qapA:
3.6		 3qipA-1qapA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.89A 4dqbA-1qapA:
undetectable		 4dqbA-1qapA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 11 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.92A 4dqeA-1qapA:
undetectable		 4dqeA-1qapA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 11 LEU A 148
ALA A 270
VAL A 257
VAL A 279
ILE A 277
 None
 0.89A 4dqhA-1qapA:
undetectable		 4dqhA-1qapA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 7 VAL A 112
ALA A  81
LEU A 106
ASP A  33
LEU A  30
 None
 1.21A 4l9iA-1qapA:
undetectable		 4l9iA-1qapA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 7 LEU A 255
LEU A 225
ILE A 184
VAL A 195
 None
 0.86A 4ojbA-1qapA:
0.7		 4ojbA-1qapA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 9 VAL A 279
GLY A 280
THR A 283
VAL A 166
VAL A 134
 None
 1.41A 5cp4A-1qapA:
0.0		 5cp4A-1qapA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 11 LEU A 148
VAL A 166
TYR A 137
GLY A 169
LEU A 141
 None
 1.41A 5hbmA-1qapA:
3.2		 5hbmA-1qapA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 ASP A  95
LEU A  14
THR A 160
GLY A  69
LEU A 127
 None
 1.31A 5m50E-1qapA:
1.5		 5m50E-1qapA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1qap QUINOLINIC ACID
PHOSPHORIBOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 LEU A 148
VAL A 166
TYR A 137
GLY A 169
LEU A 141
 None
 1.44A 6bsgA-1qapA:
3.4		 6bsgA-1qapA:
12.54