SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1qc6 EVH1 DOMAIN FROM
ENA/VASP-LIKE
PROTEIN
(Mus
musculus) 		3 / 3 TRP A1081
ALA A1084
VAL A1087
 None
 0.88A 1bdwA-1qc6A:
undetectable
1bdwB-1qc6A:
undetectable		 1bdwA-1qc6A:
6.92
1bdwB-1qc6A:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1qc6 EVH1 DOMAIN FROM
ENA/VASP-LIKE
PROTEIN
(Mus
musculus) 		4 / 7 TYR A1088
VAL A1060
TYR A1063
ILE A1036
 None
 1.20A 2xz5B-1qc6A:
undetectable
2xz5E-1qc6A:
undetectable		 2xz5B-1qc6A:
20.47
2xz5E-1qc6A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1qc6 EVH1 DOMAIN FROM
ENA/VASP-LIKE
PROTEIN
(Mus
musculus) 		4 / 8 ILE A1036
TYR A1088
VAL A1060
TYR A1063
 None
 1.21A 2xz5A-1qc6A:
undetectable
2xz5C-1qc6A:
undetectable		 2xz5A-1qc6A:
20.47
2xz5C-1qc6A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1qc6 EVH1 DOMAIN FROM
ENA/VASP-LIKE
PROTEIN
(Mus
musculus) 		4 / 8 ILE A1036
TYR A1088
VAL A1060
TYR A1063
 None
 1.20A 2xz5C-1qc6A:
undetectable
2xz5D-1qc6A:
undetectable		 2xz5C-1qc6A:
20.47
2xz5D-1qc6A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1qc6 EVH1 DOMAIN FROM
ENA/VASP-LIKE
PROTEIN
(Mus
musculus) 		4 / 7 ILE A1036
TYR A1088
VAL A1060
TYR A1063
 None
 1.20A 2xz5D-1qc6A:
undetectable
2xz5E-1qc6A:
undetectable		 2xz5D-1qc6A:
20.47
2xz5E-1qc6A:
20.47