SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qcj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		5 / 9 PHE A  90
TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 ( 4.7A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.46A 1mrgA-1qcjA:
30.6		 1mrgA-1qcjA:
31.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 8 TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.33A 1mrjA-1qcjA:
30.4		 1mrjA-1qcjA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 8 TYR A 123
ILE A 171
SER A 175
ARG A 179
 APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 (-1.7A)
APT  A 901 (-3.0A)
 0.65A 1mrjA-1qcjA:
30.4		 1mrjA-1qcjA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		3 / 3 ARG A 241
ASP A 248
ASN A 185
 None
 0.88A 1nbhA-1qcjA:
undetectable		 1nbhA-1qcjA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		3 / 3 ARG A 241
ASP A 248
ASN A 185
 None
 0.89A 1nbhD-1qcjA:
undetectable		 1nbhD-1qcjA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 6 PHE A  90
ASN A  91
ARG A  67
ASN A  70
 APT  A 901 ( 4.7A)
None
None
None
 1.37A 1t9uA-1qcjA:
0.0		 1t9uA-1qcjA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		5 / 10 ALA A  27
LEU A  23
LEU A  71
ALA A 178
SER A 212
 None
 1.06A 2bxgB-1qcjA:
undetectable		 2bxgB-1qcjA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 5 GLN A 139
ALA A 194
GLN A 143
ILE A 144
 None
 1.21A 2z0aA-1qcjA:
undetectable		 2z0aA-1qcjA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 6 ASN A 198
TYR A 123
GLU A 176
ILE A 183
 None
APT  A 901 (-4.7A)
APT  A 901 ( 3.6A)
None
 1.06A 3q5sA-1qcjA:
undetectable		 3q5sA-1qcjA:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		5 / 10 TYR A  72
TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-3.9A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.59A 3u6tA-1qcjA:
30.9		 3u6tA-1qcjA:
30.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 7 GLY A 257
GLY A 256
TYR A 254
ASN A  42
 None
 0.94A 4fgkB-1qcjA:
undetectable		 4fgkB-1qcjA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 7 LEU A 168
VAL A 169
LYS A 133
GLU A 127
 None
 0.99A 4lb2A-1qcjA:
0.0		 4lb2A-1qcjA:
17.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 5 TYR A  72
TYR A 123
ILE A 171
ARG A 179
 APT  A 901 (-3.9A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 (-3.0A)
 0.37A 4o0oA-1qcjA:
31.0		 4o0oA-1qcjA:
30.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		3 / 3 GLU A 176
ALA A 177
PHE A 180
 APT  A 901 ( 3.6A)
None
None
 0.66A 4v1fA-1qcjA:
undetectable		 4v1fA-1qcjA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		3 / 3 GLU A 176
ALA A 177
PHE A 180
 APT  A 901 ( 3.6A)
None
None
 0.62A 4v1fC-1qcjA:
undetectable		 4v1fC-1qcjA:
14.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		6 / 9 TYR A  72
PHE A  90
TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-3.9A)
APT  A 901 ( 4.7A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.59A 4yp2B-1qcjA:
31.0		 4yp2B-1qcjA:
30.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		5 / 8 LEU A  54
ALA A 170
LEU A  64
LEU A  66
LEU A  23
 None
 0.95A 4z90A-1qcjA:
undetectable
4z90B-1qcjA:
undetectable
4z90C-1qcjA:
undetectable
4z90D-1qcjA:
undetectable
4z90E-1qcjA:
undetectable		 4z90A-1qcjA:
23.78
4z90B-1qcjA:
23.78
4z90C-1qcjA:
23.78
4z90D-1qcjA:
23.78
4z90E-1qcjA:
23.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		6 / 9 TYR A  72
PHE A  90
TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-3.9A)
APT  A 901 ( 4.7A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.58A 5cf9B-1qcjA:
31.1		 5cf9B-1qcjA:
30.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		4 / 8 MET A 173
LEU A  54
ILE A 144
THR A  11
 None
 0.87A 5uihA-1qcjA:
undetectable		 5uihA-1qcjA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1qcj POKEWEED ANTIVIRAL
PROTEIN
(Phytolacca
americana) 		6 / 6 TYR A  72
VAL A  73
TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-3.9A)
APT  A 901 (-3.4A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.63A 5z3jA-1qcjA:
32.4		 5z3jA-1qcjA:
27.92