SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 121
ASN A  82
ILE A  85
ASN A  84
 None
 0.92A 1e06A-1qcqA:
undetectable		 1e06A-1qcqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  57
TYR A  61
VAL A 103
ILE A  55
 None
 1.01A 1p7rA-1qcqA:
undetectable		 1p7rA-1qcqA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 121
LEU A  53
ILE A 107
LEU A 111
 None
 1.00A 2byoA-1qcqA:
0.8		 2byoA-1qcqA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  79
ILE A  74
SER A  21
GLY A  40
 None
 0.84A 4ac9C-1qcqA:
undetectable		 4ac9C-1qcqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  79
ILE A  74
SER A  21
GLY A  40
 None
 0.76A 4acaC-1qcqA:
undetectable		 4acaC-1qcqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  79
ILE A  74
SER A  21
GLY A  40
 None
 0.79A 4acbC-1qcqA:
undetectable		 4acbC-1qcqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  51
ILE A  74
PRO A  41
LEU A 110
ILE A  68
 None
 0.97A 4pd4C-1qcqA:
undetectable		 4pd4C-1qcqA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1qcq PROTEIN (UBIQUITIN
CONJUGATING ENZYME)
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  53
SER A  54
PRO A  66
VAL A 103
ILE A  68
 None
 1.25A 6ef6A-1qcqA:
undetectable		 6ef6A-1qcqA:
20.06