SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 10 ALA A 281
PHE A 284
GLY A 245
LEU A 302
LEU A 307
 None
 1.39A 1cmcA-1qd1A:
undetectable
1cmcB-1qd1A:
undetectable		 1cmcA-1qd1A:
14.77
1cmcB-1qd1A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 8 THR A  30
PRO A  31
GLY A  32
CYH A  33
 None
 0.30A 1h4oB-1qd1A:
undetectable		 1h4oB-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 9 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 1.02A 1h4oD-1qd1A:
0.1		 1h4oD-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 9 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 1.02A 1h4oF-1qd1A:
0.1		 1h4oF-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 8 THR A  30
PRO A  31
GLY A  32
CYH A  33
 None
 0.37A 1h4oG-1qd1A:
undetectable		 1h4oG-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 9 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 0.97A 1h4oH-1qd1A:
0.1		 1h4oH-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 9 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 1.02A 1hd2A-1qd1A:
0.0		 1hd2A-1qd1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 4 ALA A 232
ARG A 193
GLN A 233
GLU A  81
 None
None
FON  A 330 (-3.2A)
None
 1.24A 1lqtB-1qd1A:
0.0		 1lqtB-1qd1A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 4 ALA A 232
ARG A 193
GLN A 233
GLU A  81
 None
None
FON  A 330 (-3.2A)
None
 1.22A 1lquB-1qd1A:
0.0		 1lquB-1qd1A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 8 THR A  30
PRO A  31
GLY A  32
CYH A  33
 None
 0.32A 1oc3A-1qd1A:
undetectable		 1oc3A-1qd1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 9 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 0.99A 1oc3B-1qd1A:
0.0		 1oc3B-1qd1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 PHE A 241
ILE A 322
PRO A 274
GLU A 323
 None
 1.06A 1oniA-1qd1A:
2.5
1oniB-1qd1A:
2.3		 1oniA-1qd1A:
19.94
1oniB-1qd1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 5 PHE A 241
ILE A 322
PRO A 274
GLU A 323
 None
 1.19A 1oniG-1qd1A:
2.5
1oniH-1qd1A:
2.4		 1oniG-1qd1A:
19.94
1oniH-1qd1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 ILE A 322
PRO A 274
GLU A 323
PHE A 241
 None
 1.05A 1oniG-1qd1A:
2.5
1oniI-1qd1A:
undetectable		 1oniG-1qd1A:
19.94
1oniI-1qd1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 ARG A  67
VAL A 123
GLY A 177
 None
 0.61A 2avvE-1qd1A:
undetectable		 2avvE-1qd1A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 LEU A 246
PHE A 250
PHE A 185
LEU A 269
 None
 0.94A 2eikC-1qd1A:
undetectable
2eikJ-1qd1A:
undetectable		 2eikC-1qd1A:
20.17
2eikJ-1qd1A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 6 HIS A  82
ASN A 186
GLN A 268
THR A  44
 GOL  A 480 ( 4.1A)
FON  A 330 (-4.0A)
FON  A 330 (-3.0A)
FON  A 330 (-3.1A)
 1.21A 2hkkA-1qd1A:
undetectable		 2hkkA-1qd1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 10 THR A  30
PRO A  31
GLY A  32
CYH A  33
LEU A  63
 None
 1.06A 2vl2A-1qd1A:
0.1
2vl2C-1qd1A:
0.0		 2vl2A-1qd1A:
22.63
2vl2C-1qd1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 12 PHE A  51
ALA A  28
ALA A 108
ALA A 176
THR A 174
 None
 1.33A 2x2nA-1qd1A:
undetectable		 2x2nA-1qd1A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 10 ILE A 187
GLY A 266
SER A 267
TYR A 285
ALA A 281
 None
 0.92A 2yk1H-1qd1A:
0.0
2yk1L-1qd1A:
0.0		 2yk1H-1qd1A:
22.59
2yk1L-1qd1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 5 LEU A 269
GLY A 271
THR A  50
VAL A   8
 None
 1.06A 3wrkD-1qd1A:
undetectable		 3wrkD-1qd1A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 5 SER A  40
GLU A  13
THR A  47
TYR A  49
 None
 1.48A 3zs3A-1qd1A:
0.0		 3zs3A-1qd1A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 6 LEU A   4
VAL A   5
ASP A  57
GLU A  56
 None
 0.90A 4g24A-1qd1A:
undetectable		 4g24A-1qd1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 THR A 236
LEU A 309
ASN A 188
LEU A 312
 None
 1.12A 4ib4A-1qd1A:
0.0		 4ib4A-1qd1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 GLU A 287
THR A 248
HIS A 247
 None
 0.75A 4q15A-1qd1A:
0.9		 4q15A-1qd1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 GLU A 287
THR A 248
HIS A 247
 None
 0.73A 4q15B-1qd1A:
1.0		 4q15B-1qd1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 GLU A 287
THR A 248
HIS A 247
 None
 0.70A 4ydqB-1qd1A:
undetectable		 4ydqB-1qd1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 LEU A 246
PHE A 250
PHE A 185
LEU A 269
 None
 0.99A 5b3sP-1qd1A:
undetectable		 5b3sP-1qd1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 ASP A  89
LEU A 182
ARG A 179
 None
FON  A 330 ( 4.5A)
FON  A 330 (-3.7A)
 0.60A 5e8qA-1qd1A:
undetectable		 5e8qA-1qd1A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 8 ILE A  23
THR A  47
VAL A  38
TYR A  49
GLU A  13
 None
 1.38A 5ecnD-1qd1A:
undetectable		 5ecnD-1qd1A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 6 VAL A  38
TYR A  49
ILE A  20
ASP A  21
 None
 1.21A 5iwuA-1qd1A:
undetectable		 5iwuA-1qd1A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 7 LEU A 246
PHE A 250
PHE A 185
LEU A 269
 None
 0.98A 5iy5C-1qd1A:
undetectable
5iy5J-1qd1A:
undetectable		 5iy5C-1qd1A:
21.02
5iy5J-1qd1A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		5 / 8 ALA A 281
LEU A 183
LEU A 238
LEU A 309
LEU A 269
 None
 1.34A 5jqbA-1qd1A:
undetectable
5jqbB-1qd1A:
undetectable		 5jqbA-1qd1A:
22.66
5jqbB-1qd1A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		3 / 3 ARG A 301
PHE A 284
LEU A 278
 None
 0.86A 5veuA-1qd1A:
undetectable		 5veuA-1qd1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 6 LEU A 246
PHE A 250
PHE A 185
LEU A 269
 None
 0.94A 5x19P-1qd1A:
undetectable		 5x19P-1qd1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 5 LEU A 246
PHE A 250
PHE A 185
LEU A 269
 None
 0.93A 5x1bP-1qd1A:
undetectable		 5x1bP-1qd1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qd1 FORMIMINOTRANSFERASE
-CYCLODEAMINASE
(Sus
scrofa) 		4 / 6 ILE A 222
ALA A 196
ARG A 193
ASP A 227
 GOL  A 480 (-4.3A)
None
None
None
 1.11A 6hu9m-1qd1A:
0.0
6hu9q-1qd1A:
undetectable		 6hu9m-1qd1A:
20.19
6hu9q-1qd1A:
20.00