SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
 None
 0.73A 1rtsA-1qdnA:
undetectable		 1rtsA-1qdnA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		5 / 10 LEU A  18
ASN A  20
LEU A  64
LEU A 102
PHE A 125
 None
None
SO4  A 501 ( 4.4A)
None
None
 1.43A 1zucA-1qdnA:
undetectable		 1zucA-1qdnA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		5 / 12 LEU A  18
PHE A 101
ILE A 196
LEU A 147
ILE A  99
 None
 1.11A 3gwxB-1qdnA:
undetectable		 3gwxB-1qdnA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 ARG A   4
VAL A  80
MET A   6
GLN A  33
 None
 0.78A 3remA-1qdnA:
undetectable		 3remA-1qdnA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 ARG A   4
VAL A  80
MET A   6
GLN A  33
 None
 0.78A 3remB-1qdnA:
undetectable		 3remB-1qdnA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		5 / 9 VAL A  24
VAL A  23
VAL A  37
GLY A  32
SER A  31
 None
BME  A 400 (-4.3A)
None
None
None
 1.17A 4fwdA-1qdnA:
undetectable		 4fwdA-1qdnA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		5 / 9 VAL A  24
VAL A  23
VAL A  80
GLY A  32
SER A  31
 None
BME  A 400 (-4.3A)
None
None
None
 1.24A 4fwdA-1qdnA:
undetectable		 4fwdA-1qdnA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 7 PHE A 140
LEU A 147
GLY A 146
PHE A 145
 None
 0.68A 5h3aB-1qdnA:
undetectable		 5h3aB-1qdnA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 PHE A  85
VAL A 174
ILE A 152
ILE A 122
 None
 0.91A 5hw8H-1qdnA:
undetectable		 5hw8H-1qdnA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 7 PHE A 140
LEU A 147
GLY A 146
PHE A 145
 None
 0.68A 5x5qC-1qdnA:
undetectable		 5x5qC-1qdnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
 None
 0.69A 5x5qD-1qdnA:
0.0		 5x5qD-1qdnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
 None
 0.68A 5x5qF-1qdnA:
undetectable		 5x5qF-1qdnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 1qdn PROTEIN
(N-ETHYLMALEIMIDE
SENSITIVE FUSION
PROTEIN (NSF))
(Cricetulus
griseus) 		5 / 11 PHE A 125
ASN A 180
LEU A 176
GLY A 175
PHE A 130
 None
None
BME  A 401 (-4.1A)
None
None
 1.18A 6r2eG-1qdnA:
0.0		 6r2eG-1qdnA:
21.71