SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qe0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA206_1 (CARDIAC TROPONIN C)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 8	GLN A 126 GLU A 130 GLU A 44 MET A 110	None	1.05A	1dtlA-1qe0A: undetectable	1dtlA-1qe0A: 19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 10	GLU A 80 THR A 82 ARG A 112 GLN A 126 GLU A 130 GLY A 286	None	0.82A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 10	GLU A 80 THR A 82 ARG A 112 GLU A 130 TYR A 262 GLY A 286	None	0.99A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	GLU A 80 THR A 82 TYR A 106 GLN A 126 GLY A 286	None	0.87A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	GLU A 80 THR A 82 TYR A 106 TYR A 262 GLY A 286	None	0.86A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 286	None	1.17A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 287	None	0.89A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_A_HISA450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	THR A 82 TYR A 106 ARG A 257 TYR A 262 GLY A 286	None	1.18A	1httA-1qe0A: 33.8	1httA-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_B_HISB450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	GLU A 80 THR A 82 ARG A 112 GLN A 126 GLU A 130 GLY A 286 TYR A 289 GLY A 305	None	0.79A	1httB-1qe0A: 32.7	1httB-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_B_HISB450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	THR A 82 ARG A 112 GLN A 126 GLU A 130 TYR A 262 GLY A 286 TYR A 289 GLY A 305	None	0.93A	1httB-1qe0A: 32.7	1httB-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_B_HISB450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	7 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 286 TYR A 289 GLY A 305	None	1.07A	1httB-1qe0A: 32.7	1httB-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_B_HISB450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 287 GLY A 305	None	1.27A	1httB-1qe0A: 32.7	1httB-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_C_HISC450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	GLU A 80 GLN A 126 TYR A 262 GLY A 286 ALA A 307	None	1.25A	1httC-1qe0A: 33.7	1httC-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_C_HISC450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	GLU A 80 THR A 82 GLN A 126 GLU A 130 GLY A 286 TYR A 289 GLY A 305 ALA A 307	None	0.82A	1httC-1qe0A: 33.7	1httC-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_C_HISC450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	THR A 82 GLN A 126 GLU A 130 TYR A 262 GLY A 286 TYR A 289 GLY A 305 ALA A 307	None	0.88A	1httC-1qe0A: 33.7	1httC-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_C_HISC450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 286 TYR A 289 GLY A 305 ALA A 307	None	1.03A	1httC-1qe0A: 33.7	1httC-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_C_HISC450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 287 GLY A 305	None	1.25A	1httC-1qe0A: 33.7	1httC-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_D_HISD450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	GLU A 80 ARG A 112 GLN A 126 GLY A 285 ALA A 307	None	1.20A	1httD-1qe0A: 32.7	1httD-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_D_HISD450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	GLU A 80 THR A 82 ARG A 112 GLN A 126 GLU A 130 GLY A 286 GLY A 305 ALA A 307	None	0.80A	1httD-1qe0A: 32.7	1httD-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_D_HISD450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	8 / 12	THR A 82 ARG A 112 GLN A 126 GLU A 130 TYR A 262 GLY A 286 GLY A 305 ALA A 307	None	1.00A	1httD-1qe0A: 32.7	1httD-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_D_HISD450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 286 GLY A 305	None	1.19A	1httD-1qe0A: 32.7	1httD-1qe0A: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HTT_D_HISD450_0 (HISTIDYL-TRNA SYNTHETASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 12	THR A 82 GLU A 130 ARG A 257 TYR A 262 GLY A 287 GLY A 305	None	1.28A	1httD-1qe0A: 32.7	1httD-1qe0A: 38.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1872_0 (FPRA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 5	SER A 231 ASN A 228 ALA A 170 GLU A 174	None	1.36A	1lqtA-1qe0A: undetectable 1lqtB-1qe0A: undetectable	1lqtA-1qe0A: 23.06 1lqtB-1qe0A: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1429_0 (FPRA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 5	SER A 231 ASN A 228 ALA A 170 GLU A 174	None	1.36A	1lquA-1qe0A: undetectable 1lquB-1qe0A: undetectable	1lquA-1qe0A: 23.06 1lquB-1qe0A: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEB_A_HSMA145_1 (D7R4 PROTEIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 7	ILE A 38 ARG A 39 TYR A 105 ASP A 27	None	0.98A	2qebA-1qe0A: undetectable	2qebA-1qe0A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEB_B_HSMB145_1 (D7R4 PROTEIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 7	ILE A 38 ARG A 39 TYR A 105 ASP A 27	None	0.91A	2qebB-1qe0A: undetectable	2qebB-1qe0A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_A_IMNA2_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	PHE A 127 HIS A 149 LEU A 159 LEU A 29 TYR A 33	None	1.25A	3adsA-1qe0A: 0.0	3adsA-1qe0A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_A_IMNA2_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	PHE A 127 HIS A 149 LEU A 159 PHE A 306 TYR A 33	None	1.39A	3adsA-1qe0A: 0.0	3adsA-1qe0A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_A_IMNA2_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	PHE A 127 HIS A 149 LEU A 159 LEU A 29 TYR A 33	None	1.26A	3adxA-1qe0A: 0.0	3adxA-1qe0A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADX_A_IMNA2_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	PHE A 127 HIS A 149 LEU A 159 PHE A 306 TYR A 33	None	1.36A	3adxA-1qe0A: 0.0	3adxA-1qe0A: 23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EIG_A_MTXA200_1 (DIHYDROFOLATE REDUCTASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	ILE A 304 ALA A 141 LEU A 242 ARG A 257 TYR A 234	None	1.45A	3eigA-1qe0A: undetectable	3eigA-1qe0A: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_E_TFPE201_1 (PROTEIN S100-A4)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 7	PHE A 306 GLY A 285 PHE A 267 MET A 148	None	1.08A	3ko0D-1qe0A: 1.5 3ko0E-1qe0A: 1.5	3ko0D-1qe0A: 12.62 3ko0E-1qe0A: 12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LS4_H_TCIH220_1 (HEAVY CHAIN OF ANTIBODY FAB FRAGMENT)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 10	VAL A 129 VAL A 143 LEU A 144 GLY A 305 GLY A 287	None	1.29A	3ls4H-1qe0A: undetectable	3ls4H-1qe0A: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGL_A_GLYA301_0 (GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 8	GLY A 81 THR A 82 ARG A 112 GLN A 126	None	0.50A	3rglA-1qe0A: 10.0	3rglA-1qe0A: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ7_B_SAMB302_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 5	TYR A 151 SER A 309 ASP A 272 ILE A 280	None	1.27A	3uj7B-1qe0A: undetectable	3uj7B-1qe0A: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BQF_B_QPSB951_1 (ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 8	ARG A 87 GLU A 44 LYS A 70 ARG A 73	None	1.12A	4bqfB-1qe0A: undetectable	4bqfB-1qe0A: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_I_IPHI101_0 (INSULIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	LEU A 283 ILE A 150 LEU A 156 LEU A 317 ALA A 316	None	0.98A	4p65B-1qe0A: undetectable 4p65D-1qe0A: undetectable 4p65I-1qe0A: undetectable 4p65J-1qe0A: undetectable	4p65B-1qe0A: 6.37 4p65D-1qe0A: 6.37 4p65I-1qe0A: 3.10 4p65J-1qe0A: 6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P65_K_IPHK101_0 (INSULIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	LEU A 283 ILE A 150 LEU A 156 LEU A 317 ALA A 316	None	1.01A	4p65F-1qe0A: undetectable 4p65H-1qe0A: undetectable 4p65K-1qe0A: undetectable 4p65L-1qe0A: undetectable	4p65F-1qe0A: 6.37 4p65H-1qe0A: 6.37 4p65K-1qe0A: 3.10 4p65L-1qe0A: 6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_ACTC202_0 (RETINOL-BINDING PROTEIN 2)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 6	TYR A 261 GLU A 80 THR A 82 LEU A 259	None	1.50A	4qzuC-1qe0A: undetectable	4qzuC-1qe0A: 15.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RDX_A_HISA502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 7	THR A 82 GLU A 130 TYR A 262 GLY A 286 TYR A 289 GLY A 305	None	0.77A	4rdxA-1qe0A: 38.1	4rdxA-1qe0A: 42.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_A_IMNA501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	6 / 12	PHE A 127 SER A 153 HIS A 149 PHE A 306 LEU A 29 TYR A 33	None	1.43A	4xumA-1qe0A: 0.0	4xumA-1qe0A: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_ACTA605_0 (SERUM ALBUMIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 6	GLY A 303 GLU A 135 ARG A 288 ASN A 290	None	1.28A	4zbqA-1qe0A: undetectable	4zbqA-1qe0A: 22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_A_HISA502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	9 / 12	GLU A 80 ARG A 112 GLN A 126 GLU A 130 TYR A 262 GLY A 286 TYR A 289 GLY A 305 ALA A 307	None	0.95A	5e3iA-1qe0A: 34.3	5e3iA-1qe0A: 40.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_A_HISA502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	9 / 12	GLU A 80 THR A 82 ARG A 112 GLN A 126 GLU A 130 TYR A 262 GLY A 286 GLY A 305 ALA A 307	None	0.95A	5e3iA-1qe0A: 34.3	5e3iA-1qe0A: 40.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_A_HISA502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	GLU A 130 TYR A 262 TYR A 289 GLY A 305 ALA A 307	None	1.10A	5e3iA-1qe0A: 34.3	5e3iA-1qe0A: 40.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_B_HISB502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 11	GLU A 80 ARG A 112 GLN A 126 GLY A 285 ALA A 307	None	1.18A	5e3iB-1qe0A: 35.2	5e3iB-1qe0A: 40.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_B_HISB502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	10 / 11	GLU A 80 THR A 82 ARG A 112 GLN A 126 GLU A 130 TYR A 262 GLY A 286 TYR A 289 GLY A 305 ALA A 307	None	0.96A	5e3iB-1qe0A: 35.2	5e3iB-1qe0A: 40.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5E3I_B_HISB502_0 (HISTIDINE--TRNA LIGASE)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 11	GLU A 130 TYR A 262 TYR A 289 GLY A 305 ALA A 307	None	1.09A	5e3iB-1qe0A: 35.2	5e3iB-1qe0A: 40.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7P_B_9SCB601_1 (SERUM ALBUMIN)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	4 / 6	PHE A 306 TYR A 151 LEU A 26 SER A 153	None	1.47A	6a7pB-1qe0A: undetectable	6a7pB-1qe0A: 21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_B_QPSB601_1 (-)	1qe0	HISTIDINE--TRNA LIGASE (Staphylococcus aureus)	5 / 12	THR A 224 VAL A 147 GLU A 268 CYH A 284 GLY A 285	None	1.23A	6gngB-1qe0A: 2.7	6gngB-1qe0A: 20.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA206_1","CARDIAC TROPONIN C","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"GLN A 126;GLU A 130;GLU A  44;MET A 110","None","1.05A","1dtlA-1qe0A:undetectable","1dtlA-1qe0A:19.66"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"GLU A  80;THR A  82;ARG A 112;GLN A 126;GLU A 130;GLY A 286","None","0.82A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"GLU A  80;THR A  82;ARG A 112;GLU A 130;TYR A 262;GLY A 286","None","0.99A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A  80;THR A  82;TYR A 106;GLN A 126;GLY A 286","None","0.87A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A  80;THR A  82;TYR A 106;TYR A 262;GLY A 286","None","0.86A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 286","None","1.17A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 287","None","0.89A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_A_HISA450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"THR A  82;TYR A 106;ARG A 257;TYR A 262;GLY A 286","None","1.18A","1httA-1qe0A:33.8","1httA-1qe0A:38.55"],["1HTT_B_HISB450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"GLU A  80;THR A  82;ARG A 112;GLN A 126;GLU A 130;GLY A 286;TYR A 289;GLY A 305","None","0.79A","1httB-1qe0A:32.7","1httB-1qe0A:38.55"],["1HTT_B_HISB450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"THR A  82;ARG A 112;GLN A 126;GLU A 130;TYR A 262;GLY A 286;TYR A 289;GLY A 305","None","0.93A","1httB-1qe0A:32.7","1httB-1qe0A:38.55"],["1HTT_B_HISB450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",7,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 286;TYR A 289;GLY A 305","None","1.07A","1httB-1qe0A:32.7","1httB-1qe0A:38.55"],["1HTT_B_HISB450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 287;GLY A 305","None","1.27A","1httB-1qe0A:32.7","1httB-1qe0A:38.55"],["1HTT_C_HISC450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A  80;GLN A 126;TYR A 262;GLY A 286;ALA A 307","None","1.25A","1httC-1qe0A:33.7","1httC-1qe0A:38.55"],["1HTT_C_HISC450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"GLU A  80;THR A  82;GLN A 126;GLU A 130;GLY A 286;TYR A 289;GLY A 305;ALA A 307","None","0.82A","1httC-1qe0A:33.7","1httC-1qe0A:38.55"],["1HTT_C_HISC450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"THR A  82;GLN A 126;GLU A 130;TYR A 262;GLY A 286;TYR A 289;GLY A 305;ALA A 307","None","0.88A","1httC-1qe0A:33.7","1httC-1qe0A:38.55"],["1HTT_C_HISC450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 286;TYR A 289;GLY A 305;ALA A 307","None","1.03A","1httC-1qe0A:33.7","1httC-1qe0A:38.55"],["1HTT_C_HISC450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 287;GLY A 305","None","1.25A","1httC-1qe0A:33.7","1httC-1qe0A:38.55"],["1HTT_D_HISD450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A  80;ARG A 112;GLN A 126;GLY A 285;ALA A 307","None","1.20A","1httD-1qe0A:32.7","1httD-1qe0A:38.55"],["1HTT_D_HISD450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"GLU A  80;THR A  82;ARG A 112;GLN A 126;GLU A 130;GLY A 286;GLY A 305;ALA A 307","None","0.80A","1httD-1qe0A:32.7","1httD-1qe0A:38.55"],["1HTT_D_HISD450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",8,"THR A  82;ARG A 112;GLN A 126;GLU A 130;TYR A 262;GLY A 286;GLY A 305;ALA A 307","None","1.00A","1httD-1qe0A:32.7","1httD-1qe0A:38.55"],["1HTT_D_HISD450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 286;GLY A 305","None","1.19A","1httD-1qe0A:32.7","1httD-1qe0A:38.55"],["1HTT_D_HISD450_0","HISTIDYL-TRNA SYNTHETASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"THR A  82;GLU A 130;ARG A 257;TYR A 262;GLY A 287;GLY A 305","None","1.28A","1httD-1qe0A:32.7","1httD-1qe0A:38.55"],["1LQT_A_ACTA1872_0","FPRA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"SER A 231;ASN A 228;ALA A 170;GLU A 174","None","1.36A","1lqtA-1qe0A:undetectable;1lqtB-1qe0A:undetectable","1lqtA-1qe0A:23.06;1lqtB-1qe0A:23.06"],["1LQU_A_ACTA1429_0","FPRA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"SER A 231;ASN A 228;ALA A 170;GLU A 174","None","1.36A","1lquA-1qe0A:undetectable;1lquB-1qe0A:undetectable","1lquA-1qe0A:23.06;1lquB-1qe0A:23.06"],["2QEB_A_HSMA145_1","D7R4 PROTEIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"ILE A  38;ARG A  39;TYR A 105;ASP A  27","None","0.98A","2qebA-1qe0A:undetectable","2qebA-1qe0A:15.51"],["2QEB_B_HSMB145_1","D7R4 PROTEIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"ILE A  38;ARG A  39;TYR A 105;ASP A  27","None","0.91A","2qebB-1qe0A:undetectable","2qebB-1qe0A:15.51"],["3ADS_A_IMNA2_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"PHE A 127;HIS A 149;LEU A 159;LEU A  29;TYR A  33","None","1.25A","3adsA-1qe0A:0.0","3adsA-1qe0A:23.56"],["3ADS_A_IMNA2_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"PHE A 127;HIS A 149;LEU A 159;PHE A 306;TYR A  33","None","1.39A","3adsA-1qe0A:0.0","3adsA-1qe0A:23.56"],["3ADX_A_IMNA2_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"PHE A 127;HIS A 149;LEU A 159;LEU A  29;TYR A  33","None","1.26A","3adxA-1qe0A:0.0","3adxA-1qe0A:23.56"],["3ADX_A_IMNA2_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"PHE A 127;HIS A 149;LEU A 159;PHE A 306;TYR A  33","None","1.36A","3adxA-1qe0A:0.0","3adxA-1qe0A:23.56"],["3EIG_A_MTXA200_1","DIHYDROFOLATE REDUCTASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"ILE A 304;ALA A 141;LEU A 242;ARG A 257;TYR A 234","None","1.45A","3eigA-1qe0A:undetectable","3eigA-1qe0A:18.65"],["3KO0_E_TFPE201_1","PROTEIN S100-A4;PROTEIN S100-A4","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"PHE A 306;GLY A 285;PHE A 267;MET A 148","None","1.08A","3ko0D-1qe0A:1.5;3ko0E-1qe0A:1.5","3ko0D-1qe0A:12.62;3ko0E-1qe0A:12.62"],["3LS4_H_TCIH220_1","HEAVY CHAIN OF ANTIBODY FAB FRAGMENT","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"VAL A 129;VAL A 143;LEU A 144;GLY A 305;GLY A 287","None","1.29A","3ls4H-1qe0A:undetectable","3ls4H-1qe0A:18.66"],["3RGL_A_GLYA301_0","GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"GLY A  81;THR A  82;ARG A 112;GLN A 126","None","0.50A","3rglA-1qe0A:10.0","3rglA-1qe0A:22.85"],["3UJ7_B_SAMB302_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"TYR A 151;SER A 309;ASP A 272;ILE A 280","None","1.27A","3uj7B-1qe0A:undetectable","3uj7B-1qe0A:21.59"],["4BQF_B_QPSB951_1","ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"ARG A  87;GLU A  44;LYS A  70;ARG A  73","None","1.12A","4bqfB-1qe0A:undetectable","4bqfB-1qe0A:19.91"],["4P65_I_IPHI101_0","INSULIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"LEU A 283;ILE A 150;LEU A 156;LEU A 317;ALA A 316","None","0.98A","4p65B-1qe0A:undetectable;4p65D-1qe0A:undetectable;4p65I-1qe0A:undetectable;4p65J-1qe0A:undetectable","4p65B-1qe0A:6.37;4p65D-1qe0A:6.37;4p65I-1qe0A:3.10;4p65J-1qe0A:6.37"],["4P65_K_IPHK101_0","INSULIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"LEU A 283;ILE A 150;LEU A 156;LEU A 317;ALA A 316","None","1.01A","4p65F-1qe0A:undetectable;4p65H-1qe0A:undetectable;4p65K-1qe0A:undetectable;4p65L-1qe0A:undetectable","4p65F-1qe0A:6.37;4p65H-1qe0A:6.37;4p65K-1qe0A:3.10;4p65L-1qe0A:6.37"],["4QZU_C_ACTC202_0","RETINOL-BINDING PROTEIN 2","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"TYR A 261;GLU A  80;THR A  82;LEU A 259","None","1.50A","4qzuC-1qe0A:undetectable","4qzuC-1qe0A:15.01"],["4RDX_A_HISA502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"THR A  82;GLU A 130;TYR A 262;GLY A 286;TYR A 289;GLY A 305","None","0.77A","4rdxA-1qe0A:38.1","4rdxA-1qe0A:42.02"],["4XUM_A_IMNA501_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",6,"PHE A 127;SER A 153;HIS A 149;PHE A 306;LEU A  29;TYR A  33","None","1.43A","4xumA-1qe0A:0.0","4xumA-1qe0A:22.72"],["4ZBQ_A_ACTA605_0","SERUM ALBUMIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"GLY A 303;GLU A 135;ARG A 288;ASN A 290","None","1.28A","4zbqA-1qe0A:undetectable","4zbqA-1qe0A:22.35"],["5E3I_A_HISA502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",9,"GLU A  80;ARG A 112;GLN A 126;GLU A 130;TYR A 262;GLY A 286;TYR A 289;GLY A 305;ALA A 307","None","0.95A","5e3iA-1qe0A:34.3","5e3iA-1qe0A:40.09"],["5E3I_A_HISA502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",9,"GLU A  80;THR A  82;ARG A 112;GLN A 126;GLU A 130;TYR A 262;GLY A 286;GLY A 305;ALA A 307","None","0.95A","5e3iA-1qe0A:34.3","5e3iA-1qe0A:40.09"],["5E3I_A_HISA502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A 130;TYR A 262;TYR A 289;GLY A 305;ALA A 307","None","1.10A","5e3iA-1qe0A:34.3","5e3iA-1qe0A:40.09"],["5E3I_B_HISB502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A  80;ARG A 112;GLN A 126;GLY A 285;ALA A 307","None","1.18A","5e3iB-1qe0A:35.2","5e3iB-1qe0A:40.09"],["5E3I_B_HISB502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",10,"GLU A  80;THR A  82;ARG A 112;GLN A 126;GLU A 130;TYR A 262;GLY A 286;TYR A 289;GLY A 305;ALA A 307","None","0.96A","5e3iB-1qe0A:35.2","5e3iB-1qe0A:40.09"],["5E3I_B_HISB502_0","HISTIDINE--TRNA LIGASE","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"GLU A 130;TYR A 262;TYR A 289;GLY A 305;ALA A 307","None","1.09A","5e3iB-1qe0A:35.2","5e3iB-1qe0A:40.09"],["6A7P_B_9SCB601_1","SERUM ALBUMIN","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",4,"PHE A 306;TYR A 151;LEU A  26;SER A 153","None","1.47A","6a7pB-1qe0A:undetectable","6a7pB-1qe0A:21.42"],["6GNG_B_QPSB601_1","-","1qe0","HISTIDINE--TRNA LIGASE","Staphylococcus aureus",5,"THR A 224;VAL A 147;GLU A 268;CYH A 284;GLY A 285","None","1.23A","6gngB-1qe0A:2.7","6gngB-1qe0A:20.74"]]