SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qf6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 ASP A 383
GLU A 357
PHE A 379
ARG A 363
 ZN  A1001 ( 4.9A)
None
AMP  A1002 (-3.7A)
AMP  A1002 (-2.7A)
 1.17A 1b2iA-1qf6A:
undetectable		 1b2iA-1qf6A:
8.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NYR_A_THRA1004_0
(THREONYL-TRNA
SYNTHETASE 1)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		7 / 10 CYH A 334
ARG A 363
ASP A 383
HIS A 385
TYR A 462
GLN A 484
HIS A 511
 ZN  A1001 (-2.3A)
AMP  A1002 (-2.7A)
ZN  A1001 ( 4.9A)
ZN  A1001 (-3.3A)
None
A  B  76 ( 3.4A)
ZN  A1001 (-3.4A)
 0.72A 1nyrA-1qf6A:
51.4		 1nyrA-1qf6A:
43.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NYR_A_THRA1004_0
(THREONYL-TRNA
SYNTHETASE 1)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 10 MET A 332
CYH A 334
ARG A 363
ASP A 383
HIS A 385
 None
ZN  A1001 (-2.3A)
AMP  A1002 (-2.7A)
ZN  A1001 ( 4.9A)
ZN  A1001 (-3.3A)
 1.04A 1nyrA-1qf6A:
51.4		 1nyrA-1qf6A:
43.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NYR_B_THRB2004_0
(THREONYL-TRNA
SYNTHETASE 1)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		7 / 10 CYH A 334
ARG A 363
ASP A 383
HIS A 385
TYR A 462
GLN A 484
HIS A 511
 ZN  A1001 (-2.3A)
AMP  A1002 (-2.7A)
ZN  A1001 ( 4.9A)
ZN  A1001 (-3.3A)
None
A  B  76 ( 3.4A)
ZN  A1001 (-3.4A)
 0.86A 1nyrB-1qf6A:
48.7		 1nyrB-1qf6A:
43.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NYR_B_THRB2004_0
(THREONYL-TRNA
SYNTHETASE 1)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		7 / 10 MET A 332
CYH A 334
ARG A 363
ASP A 383
HIS A 385
GLN A 484
HIS A 511
 None
ZN  A1001 (-2.3A)
AMP  A1002 (-2.7A)
ZN  A1001 ( 4.9A)
ZN  A1001 (-3.3A)
A  B  76 ( 3.4A)
ZN  A1001 (-3.4A)
 0.85A 1nyrB-1qf6A:
48.7		 1nyrB-1qf6A:
43.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 ILE A  70
GLY A  67
PRO A 188
PHE A 192
 None
 0.77A 1oniG-1qf6A:
1.4
1oniI-1qf6A:
3.1		 1oniG-1qf6A:
12.52
1oniI-1qf6A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 ARG A 354
SER A 409
TYR A 408
 None
 0.51A 1x70A-1qf6A:
0.1		 1x70A-1qf6A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 PRO A 464
THR A 422
PRO A 424
 None
 0.71A 2d55C-1qf6A:
undetectable		 2d55C-1qf6A:
1.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A 524
GLY A 372
HIS A 371
ARG A 476
GLY A 523
 None
None
G  B  70 ( 4.6A)
G  B  70 ( 4.0A)
None
 1.21A 2fn1A-1qf6A:
undetectable		 2fn1A-1qf6A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A 524
GLY A 372
HIS A 371
ARG A 476
GLY A 523
 None
None
G  B  70 ( 4.6A)
G  B  70 ( 4.0A)
None
 1.18A 2fn1B-1qf6A:
undetectable		 2fn1B-1qf6A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 ALA A 565
ALA A 538
ILE A 632
LEU A 640
MET A 619
 None
 1.11A 2nyrA-1qf6A:
undetectable		 2nyrA-1qf6A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 LYS A 284
ASP A 406
PHE A 280
ARG A 635
 None
 1.36A 2pk4A-1qf6A:
undetectable		 2pk4A-1qf6A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 VAL A 483
PHE A 452
ARG A 512
ARG A 520
 None
None
None
AMP  A1002 (-3.7A)
 1.24A 3bjwF-1qf6A:
0.0		 3bjwF-1qf6A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 CYH A 193
HIS A 194
PHE A 196
 None
 1.23A 3cr4X-1qf6A:
0.0		 3cr4X-1qf6A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 GLY A 101
TYR A 232
GLY A 220
MET A 199
 None
 0.92A 3e9rA-1qf6A:
undetectable		 3e9rA-1qf6A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 GLY A 101
TYR A 232
GLY A 220
MET A 199
 None
 0.95A 3e9rC-1qf6A:
undetectable		 3e9rC-1qf6A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 GLY A  38
ILE A  59
PRO A 188
VAL A 187
ILE A  70
 None
 1.17A 3ekyB-1qf6A:
undetectable		 3ekyB-1qf6A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 ASP A 161
ARG A 145
ARG A 207
 None
 0.86A 3k37A-1qf6A:
undetectable		 3k37A-1qf6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 HIS A 385
HIS A 511
MET A 509
 ZN  A1001 (-3.3A)
ZN  A1001 (-3.4A)
None
 0.84A 3mihA-1qf6A:
undetectable		 3mihA-1qf6A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		6 / 11 LEU A 537
GLY A 523
GLY A 248
ILE A 247
PRO A 539
ILE A 273
 None
 1.37A 3nu3B-1qf6A:
undetectable		 3nu3B-1qf6A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 ARG A 375
PRO A 331
PHE A 379
 C  B  74 (-3.0A)
A  B  76 ( 4.4A)
AMP  A1002 (-3.7A)
 0.85A 3thrC-1qf6A:
undetectable		 3thrC-1qf6A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 GLY A 101
THR A 221
ASN A 100
 None
 0.68A 3v4tD-1qf6A:
0.0		 3v4tD-1qf6A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A  70
ALA A  37
GLY A  38
HIS A 186
TYR A 173
 None
 1.13A 4e47A-1qf6A:
undetectable		 4e47A-1qf6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A  70
ALA A  37
GLY A  38
HIS A 186
TYR A 173
 None
 1.13A 4e47B-1qf6A:
undetectable		 4e47B-1qf6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 ILE A 416
LEU A 470
MET A 518
GLY A 516
 None
None
None
AMP  A1002 (-3.0A)
 0.94A 4hajA-1qf6A:
undetectable		 4hajA-1qf6A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 LEU A 285
PHE A 358
MET A 518
GLY A 516
LEU A 515
 None
None
None
AMP  A1002 (-3.0A)
None
 1.22A 4j7xB-1qf6A:
undetectable		 4j7xB-1qf6A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 LEU A  25
TYR A  14
ASP A  49
ASP A  46
GLY A  38
 None
 1.19A 4j7xF-1qf6A:
undetectable		 4j7xF-1qf6A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A  70
ALA A  37
GLY A  38
HIS A 186
TYR A 173
 None
 1.13A 4jdsA-1qf6A:
undetectable		 4jdsA-1qf6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 ILE A  70
ALA A  37
GLY A  38
HIS A 186
TYR A 173
 None
 1.14A 4jdsB-1qf6A:
undetectable		 4jdsB-1qf6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 ILE A  70
ALA A  37
GLY A  38
HIS A 186
TYR A 173
 None
 1.20A 4jlgA-1qf6A:
0.0		 4jlgA-1qf6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 ARG A 363
PHE A 379
GLN A 479
THR A 482
ARG A 520
 AMP  A1002 (-2.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.9A)
AMP  A1002 (-3.7A)
 0.62A 4k87A-1qf6A:
26.7		 4k87A-1qf6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 ARG A 375
GLN A 479
GLY A 481
THR A 482
ARG A 520
 C  B  74 (-3.0A)
AMP  A1002 (-3.7A)
None
AMP  A1002 (-3.9A)
AMP  A1002 (-3.7A)
 0.95A 4k87A-1qf6A:
26.7		 4k87A-1qf6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 PHE A 379
GLN A 479
GLY A 481
THR A 482
ARG A 520
 AMP  A1002 (-3.7A)
AMP  A1002 (-3.7A)
None
AMP  A1002 (-3.9A)
AMP  A1002 (-3.7A)
 0.71A 4k87A-1qf6A:
26.7		 4k87A-1qf6A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 GLU A 305
TYR A 327
GLU A 326
ARG A 325
 None
 1.12A 4mi4B-1qf6A:
0.4
4mi4C-1qf6A:
0.5		 4mi4B-1qf6A:
14.95
4mi4C-1qf6A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLU A 305
TYR A 327
GLU A 326
ARG A 325
 None
 1.12A 4mj8B-1qf6A:
0.6
4mj8C-1qf6A:
0.6		 4mj8B-1qf6A:
13.74
4mj8C-1qf6A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 4 LEU A  31
ILE A  27
PRO A   7
LEU A  57
 None
 1.13A 5eb3A-1qf6A:
undetectable		 5eb3A-1qf6A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 HIS A 175
HIS A  77
HIS A 186
 None
 0.98A 5oexA-1qf6A:
undetectable		 5oexA-1qf6A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 5 LEU A 537
PHE A 529
LEU A 525
PHE A 521
 None
 1.00A 5x19C-1qf6A:
undetectable
5x19J-1qf6A:
undetectable		 5x19C-1qf6A:
17.24
5x19J-1qf6A:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 GLU A 365
PRO A 331
ARG A 363
HIS A 385
THR A 482
 AMP  A1002 (-3.7A)
A  B  76 ( 4.4A)
AMP  A1002 (-2.7A)
ZN  A1001 (-3.3A)
AMP  A1002 (-3.9A)
 1.47A 5xioB-1qf6A:
27.2		 5xioB-1qf6A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 GLU A 365
PRO A 331
ARG A 363
HIS A 385
THR A 482
 AMP  A1002 (-3.7A)
A  B  76 ( 4.4A)
AMP  A1002 (-2.7A)
ZN  A1001 (-3.3A)
AMP  A1002 (-3.9A)
 1.50A 5xiqB-1qf6A:
14.8		 5xiqB-1qf6A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 GLY A 579
VAL A 543
MET A 593
 A  B  38 ( 4.1A)
None
None
 0.65A 5ycpA-1qf6A:
0.5		 5ycpA-1qf6A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 TYR A  14
ILE A   4
LEU A   6
ALA A  24
LEU A  31
 None
 1.41A 5zwrB-1qf6A:
undetectable		 5zwrB-1qf6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 TYR A 104
HIS A  77
MET A 181
 None
 1.10A 6af6A-1qf6A:
0.0		 6af6A-1qf6A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 10 ARG A 363
GLU A 365
PHE A 379
GLY A 516
ARG A 520
 AMP  A1002 (-2.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.0A)
AMP  A1002 (-3.7A)
 0.71A 6bniA-1qf6A:
13.0		 6bniA-1qf6A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 10 ARG A 363
GLU A 365
PHE A 379
GLY A 516
ARG A 520
 AMP  A1002 (-2.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.7A)
AMP  A1002 (-3.0A)
AMP  A1002 (-3.7A)
 0.68A 6bniB-1qf6A:
13.0		 6bniB-1qf6A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 4 HIS A 125
LEU A 233
TYR A 232
GLY A 220
 None
 1.35A 6n91A-1qf6A:
undetectable		 6n91A-1qf6A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1qf6 THREONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 4 HIS A 125
LEU A 233
TYR A 232
GLY A 220
 None
 1.34A 6n91B-1qf6A:
undetectable		 6n91B-1qf6A:
9.23