SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.31A 1dsdC-1qfuH:
undetectable		 1dsdC-1qfuH:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.31A 1dsdC-1qfuH:
undetectable		 1dsdC-1qfuH:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		3 / 3 TRP H 188
VAL H 211
PRO H 212
 None
 0.78A 1rg1A-1qfuH:
undetectable		 1rg1A-1qfuH:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		3 / 3 TRP H 188
VAL H 211
PRO H 212
 None
 0.78A 1rh0A-1qfuH:
undetectable		 1rh0A-1qfuH:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		3 / 3 ASN H  60
LEU H  82
PHE H  37
 None
 0.79A 4dajB-1qfuH:
undetectable		 4dajB-1qfuH:
19.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.41A 4m7kH-1qfuH:
25.9		 4m7kH-1qfuH:
64.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		3 / 3 VAL H 183
SER H 185
TRP H 188
 None
 1.06A 5jwaA-1qfuH:
undetectable		 5jwaA-1qfuH:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))
(Mus
musculus) 		5 / 12 LYS H  62
LEU H  82
LEU H  82
LEU H  20
GLU H  46
 None
 1.17A 5v0vA-1qfuH:
undetectable		 5v0vA-1qfuH:
18.79