SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 TRP 2 177
VAL 2  82
TRP 2 105
 None
 1.23A 1c4dC-1qgc2:
undetectable
1c4dD-1qgc2:
undetectable		 1c4dC-1qgc2:
8.05
1c4dD-1qgc2:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 123
PRO A 125
THR A 124
PRO A 154
 None
 1.25A 1dsdC-1qgcA:
undetectable		 1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 124
PRO A 154
THR A 123
PRO A 125
 None
 1.18A 1dsdC-1qgcA:
undetectable		 1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 123
PRO A 125
THR A 124
PRO A 154
 None
 1.25A 1dsdC-1qgcA:
undetectable		 1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 124
PRO A 154
THR A 123
PRO A 125
 None
 1.18A 1dsdC-1qgcA:
undetectable		 1dsdC-1qgcA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		5 / 7 THR 2  43
SER 2  42
HIS 2 209
TYR 2  98
LEU 2  94
 None
 1.32A 1ibgL-1qgc2:
0.0		 1ibgL-1qgc2:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		4 / 4 LEU 5 155
GLY 2 164
ASP 2 169
TYR 1 130
 None
 1.43A 1oxrA-1qgc5:
undetectable		 1oxrA-1qgc5:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		5 / 12 SER 3 163
TYR 3 169
LEU 1 126
LEU 5 155
PRO 5 156
 None
 1.40A 1p33B-1qgc3:
undetectable		 1p33B-1qgc3:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
(Foot-and-mouth
disease
virus) 		3 / 3 ASP 1  75
TYR 1 119
GLU 1 184
 None
 0.80A 1vm1A-1qgc1:
undetectable		 1vm1A-1qgc1:
23.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		3 / 3 TRP A  47
ARG A  99
PHE A 107
 None
 1.11A 1zeaH-1qgcA:
23.7
1zeaL-1qgcA:
14.6		 1zeaH-1qgcA:
66.82
1zeaL-1qgcA:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		4 / 5 PRO 2  71
GLY 2 193
ASN 2 190
GLY 2 118
 None
 1.11A 1zlqA-1qgc2:
undetectable		 1zlqA-1qgc2:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Foot-and-mouth
disease
virus;
Mus
musculus) 		5 / 12 GLY 5 142
TYR A  60
ALA 5 140
ASP 5 143
ARG A  99
 None
 1.39A 2avdB-1qgc5:
undetectable		 2avdB-1qgc5:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 PRO 2 176
GLY 2 164
TYR 2 162
 None
 0.67A 2vouA-1qgc2:
undetectable		 2vouA-1qgc2:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 PRO 2 176
GLY 2 164
TYR 2 162
 None
 0.55A 2vouB-1qgc2:
undetectable		 2vouB-1qgc2:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 PRO 2 176
GLY 2 164
TYR 2 162
 None
 0.57A 2vouC-1qgc2:
undetectable		 2vouC-1qgc2:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		5 / 12 THR 3 112
VAL 3 200
VAL 3 201
PHE 3  57
TYR 3 121
 None
 1.33A 2y03B-1qgc3:
undetectable		 2y03B-1qgc3:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		5 / 12 THR 3 112
VAL 3 200
VAL 3 201
PHE 3  57
TYR 3 121
 None
 1.32A 2y04B-1qgc3:
undetectable		 2y04B-1qgc3:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
(Foot-and-mouth
disease
virus) 		4 / 6 ASN 1  91
SER 1 162
ALA 1 121
HIS 1 123
 None
 1.35A 3aruA-1qgc1:
0.0		 3aruA-1qgc1:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		5 / 12 THR 3 112
VAL 3 200
VAL 3 201
PHE 3  57
TYR 3 121
 None
 1.30A 3d4sA-1qgc3:
undetectable		 3d4sA-1qgc3:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		3 / 3 TYR 3 125
TYR 2 100
GLY 3 182
 None
 0.69A 3eteB-1qgc3:
undetectable
3eteD-1qgc3:
undetectable
3eteF-1qgc3:
undetectable		 3eteB-1qgc3:
18.70
3eteD-1qgc3:
18.70
3eteF-1qgc3:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Foot-and-mouth
disease
virus;
Mus
musculus) 		3 / 3 ARG A  98
GLU A 105
TYR 5 136
 None
 0.84A 3k37B-1qgcA:
undetectable		 3k37B-1qgcA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		5 / 12 ALA 3 139
ILE 3 189
LEU 3 199
CYH 3 185
VAL 3 186
 None
 1.01A 3o7wA-1qgc3:
undetectable		 3o7wA-1qgc3:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 6 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 1.04A 3t3sB-1qgc3:
undetectable		 3t3sB-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 7 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 1.11A 3t3sC-1qgc3:
undetectable		 3t3sC-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 8 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 0.99A 3t3sE-1qgc3:
undetectable		 3t3sE-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 8 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 0.96A 3t3sF-1qgc3:
undetectable		 3t3sF-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		5 / 11 GLN A 112
MET A  34
GLY A 111
GLY A  26
ASN A  77
 None
 1.29A 3v3nA-1qgcA:
undetectable		 3v3nA-1qgcA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		5 / 11 GLN A 112
MET A  34
GLY A 111
GLY A  26
ASN A  77
 None
 1.30A 3v3nD-1qgcA:
undetectable		 3v3nD-1qgcA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		5 / 11 GLN A 112
MET A  34
GLY A 111
GLY A  26
ASN A  77
 None
 1.28A 4a99D-1qgcA:
undetectable		 4a99D-1qgcA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 6 ASN 3 106
ALA 3 203
THR 3  89
LEU 3  81
 None
 0.90A 4ejgD-1qgc3:
undetectable		 4ejgD-1qgc3:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1qgc PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Mus
musculus) 		4 / 5 TYR A  94
LEU A  81
LEU A  86
ARG A  67
 None
 1.24A 4em2A-1qgcA:
undetectable		 4em2A-1qgcA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 PHE 2 147
VAL 2 199
ILE 2 197
 None
 0.63A 4emaA-1qgc2:
undetectable		 4emaA-1qgc2:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 PHE 2  62
TYR 2 171
TYR 2  91
 None
 1.08A 4ffwA-1qgc2:
undetectable		 4ffwA-1qgc2:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 5 ALA 3 194
HIS 3 191
GLN 3 188
TYR 3 121
 None
 1.32A 4gboB-1qgc3:
undetectable		 4gboB-1qgc3:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN
(IMMUNOGLOBULIN
HEAVY CHAIN)
(Foot-and-mouth
disease
virus;
Mus
musculus) 		5 / 12 VAL A  97
ASP 5 143
PHE A 107
GLY A 106
ASP A 104
 None
 1.03A 4pevB-1qgcA:
undetectable		 4pevB-1qgcA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
(Foot-and-mouth
disease
virus;
Foot-and-mouth
disease
virus;
Foot-and-mouth
disease
virus) 		5 / 12 HIS 1 123
GLY 2 164
GLY 1 132
LEU 5 155
PRO 5 156
 None
 1.37A 4uinH-1qgc1:
undetectable
4uinL-1qgc1:
undetectable		 4uinH-1qgc1:
25.33
4uinL-1qgc1:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
(Foot-and-mouth
disease
virus) 		4 / 4 LEU 1  51
ILE 1 173
HIS 1  49
VAL 1 168
 None
 0.87A 4xyzA-1qgc1:
undetectable		 4xyzA-1qgc1:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 5 ALA 3 171
TYR 3 169
HIS 1  49
PRO 1  90
 None
 1.10A 4ze2A-1qgc3:
undetectable		 4ze2A-1qgc3:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		5 / 12 ILE 2 197
VAL 2 109
VAL 2 123
GLY 1   5
THR 1   4
 None
 1.03A 5igiA-1qgc2:
undetectable		 5igiA-1qgc2:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		5 / 12 ILE 2 197
VAL 2 109
VAL 2 123
GLY 1   5
THR 1   4
 None
 1.01A 5igjA-1qgc2:
0.0		 5igjA-1qgc2:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus;
Foot-and-mouth
disease
virus) 		5 / 12 ILE 2 197
VAL 2 109
VAL 2 123
GLY 1   5
THR 1   4
 None
 1.05A 5igpA-1qgc2:
undetectable		 5igpA-1qgc2:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus;
Foot-and-mouth
disease
virus) 		5 / 12 ILE 2 197
VAL 2 109
VAL 2 123
GLY 1   5
THR 1   4
 None
 1.03A 5igtA-1qgc2:
undetectable		 5igtA-1qgc2:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP3)
(Foot-and-mouth
disease
virus) 		4 / 7 LEU 3 211
LEU 3  45
ALA 3  48
THR 3  89
 None
 0.89A 6a7jA-1qgc3:
undetectable		 6a7jA-1qgc3:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		5 / 12 ASP 2 169
HIS 1 123
LEU 5 155
GLY 1 132
HIS 2 174
 None
 1.42A 6f3mA-1qgc2:
0.0		 6f3mA-1qgc2:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 1qgc PROTEIN (GH-LOOP
FROM VIRUS CAPSID
PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP1)
PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		5 / 12 ASP 2 169
HIS 1 123
LEU 5 155
GLY 1 132
HIS 2 174
 None
 1.44A 6f3mC-1qgc2:
0.0		 6f3mC-1qgc2:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1qgc PROTEIN (VIRUS
CAPSID PROTEIN VP2)
(Foot-and-mouth
disease
virus) 		3 / 3 ILE 2 158
THR 2 159
PRO 2 144
 None
 0.48A 6ncsA-1qgc2:
undetectable		 6ncsA-1qgc2:
20.55