SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 LEU A   7
ALA A  10
ALA A  13
ARG A  12
ARG A 274
 None
 1.28A 1cbrA-1qgdA:
undetectable		 1cbrA-1qgdA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 LEU A   7
ALA A  10
ALA A  13
ARG A  12
ARG A 274
 None
 1.28A 1cbrB-1qgdA:
undetectable		 1cbrB-1qgdA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 MET A  84
SER A  95
SER A  15
ALA A  18
 None
 1.21A 1fxvA-1qgdA:
0.0
1fxvB-1qgdA:
0.0		 1fxvA-1qgdA:
14.11
1fxvB-1qgdA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.99A 1jffB-1qgdA:
undetectable		 1jffB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ASN A 138
ALA A 134
ASP A 146
GLU A 130
 None
 1.27A 1lqtA-1qgdA:
3.3
1lqtB-1qgdA:
3.6		 1lqtA-1qgdA:
23.07
1lqtB-1qgdA:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ASN A 138
ALA A 134
ASP A 146
GLU A 130
 None
 1.26A 1lquA-1qgdA:
3.6
1lquB-1qgdA:
3.3		 1lquA-1qgdA:
23.07
1lquB-1qgdA:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.83A 1usqA-1qgdA:
undetectable		 1usqA-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.82A 1usqF-1qgdA:
undetectable		 1usqF-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 THR A 132
GLY A 377
ILE A 396
GLU A 411
ALA A 418
 None
 1.41A 1vq1A-1qgdA:
4.1		 1vq1A-1qgdA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		3 / 3 HIS A 192
ASP A 155
ASN A  64
 None
CA  A 675 (-3.3A)
None
 0.86A 1wg8B-1qgdA:
2.8		 1wg8B-1qgdA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 11 ALA A 135
ALA A 134
GLN A 136
LEU A 133
ALA A 401
 None
 1.12A 2aclE-1qgdA:
undetectable		 2aclE-1qgdA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.99A 2hxfB-1qgdA:
undetectable		 2hxfB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.99A 2hxhB-1qgdA:
undetectable		 2hxhB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.79A 2jkjE-1qgdA:
undetectable		 2jkjE-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.81A 2jklA-1qgdA:
undetectable		 2jklA-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.83A 2jklC-1qgdA:
undetectable		 2jklC-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.82A 2jklD-1qgdA:
undetectable		 2jklD-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.81A 2jklE-1qgdA:
undetectable		 2jklE-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 PRO A 429
GLY A 377
THR A 132
ILE A 396
 None
 0.81A 2jklF-1qgdA:
undetectable		 2jklF-1qgdA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 8 LEU A 173
ALA A 127
GLY A 420
ILE A 421
LEU A 169
 None
 0.90A 2o4nB-1qgdA:
undetectable		 2o4nB-1qgdA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 6 THR A 586
ARG A 483
THR A 557
ASP A 545
 None
 1.33A 2okcA-1qgdA:
undetectable		 2okcA-1qgdA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.99A 2p4nB-1qgdA:
undetectable		 2p4nB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 9 SER A  73
ILE A  11
ALA A  37
GLY A  65
LEU A  62
 None
 1.06A 2v0mB-1qgdA:
0.0		 2v0mB-1qgdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 8 LEU A 240
PRO A 238
ALA A 170
LEU A 178
ALA A 123
 None
 1.25A 2vcvF-1qgdA:
undetectable		 2vcvF-1qgdA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 8 LEU A 662
ALA A 578
LEU A 571
ALA A 567
 None
 0.82A 2vcvF-1qgdA:
undetectable		 2vcvF-1qgdA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 8 LEU A 662
ALA A 578
LEU A 571
ALA A 567
 None
 0.73A 2vcvP-1qgdA:
0.0		 2vcvP-1qgdA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.98A 2wbeB-1qgdA:
undetectable		 2wbeB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ILE A 345
CYH A 494
ALA A 556
LEU A 543
ILE A 536
 None
 1.24A 2xkwB-1qgdA:
0.0		 2xkwB-1qgdA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ALA A 227
GLY A 218
CYH A 243
LYS A 244
 None
 1.33A 2yldA-1qgdA:
undetectable		 2yldA-1qgdA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ALA A 227
GLY A 218
CYH A 243
LYS A 244
 None
 1.09A 2ylgA-1qgdA:
undetectable		 2ylgA-1qgdA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 SER A 519
LEU A 518
THR A 460
ALA A 360
ASN A 522
 None
 1.22A 3a35B-1qgdA:
undetectable		 3a35B-1qgdA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 SER A 519
LEU A 518
THR A 460
ALA A 360
ASN A 522
 None
 1.22A 3a3bA-1qgdA:
undetectable		 3a3bA-1qgdA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 PRO A 238
ILE A 120
LEU A 169
ILE A 417
ALA A 416
 None
 1.12A 3a50D-1qgdA:
undetectable		 3a50D-1qgdA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.99A 3dcoB-1qgdA:
undetectable		 3dcoB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.98A 3edlB-1qgdA:
undetectable		 3edlB-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 TYR A 407
ILE A 421
GLY A 378
LEU A 169
 None
 0.88A 3elzA-1qgdA:
undetectable		 3elzA-1qgdA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 8 LEU A 277
SER A  73
GLY A  28
PRO A  27
 None
 0.83A 3hcrA-1qgdA:
3.5		 3hcrA-1qgdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ASP A 183
HIS A 219
LEU A 277
THR A 273
GLY A  28
 None
 0.97A 3iz0B-1qgdA:
undetectable		 3iz0B-1qgdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 TYR A  80
LEU A  14
LEU A  75
TRP A 294
 None
 1.27A 3nk2X-1qgdA:
0.0		 3nk2X-1qgdA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 THR A 433
PHE A 434
ARG A 358
LEU A 387
 None
None
SO4  A 680 (-3.2A)
None
 1.08A 3qelC-1qgdA:
3.9		 3qelC-1qgdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 MET A 451
THR A 485
ASP A 511
VAL A 103
LEU A 423
 None
 1.20A 3v8vA-1qgdA:
2.3		 3v8vA-1qgdA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 8 LEU A 169
ASN A 122
GLY A 420
ILE A 421
 None
 0.89A 3wxoA-1qgdA:
0.0		 3wxoA-1qgdA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 8 LEU A 175
ASN A 122
GLY A 420
ILE A 421
 None
 0.81A 3wxoA-1qgdA:
0.0		 3wxoA-1qgdA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 11 PRO A 493
SER A 499
THR A 460
LEU A 518
GLN A 362
 None
 1.47A 3zqeA-1qgdA:
0.0
3zqeB-1qgdA:
0.0		 3zqeA-1qgdA:
19.40
3zqeB-1qgdA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ALA A 227
GLY A 218
CYH A 243
LYS A 244
 None
 1.32A 3zwiA-1qgdA:
undetectable		 3zwiA-1qgdA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		3 / 3 ASN A   9
TRP A 279
ASP A  35
 None
 1.19A 4a7tA-1qgdA:
undetectable
4a7tF-1qgdA:
undetectable		 4a7tA-1qgdA:
13.31
4a7tF-1qgdA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		3 / 3 PRO A 101
TYR A  72
GLY A  67
 None
 0.75A 4g2zA-1qgdA:
undetectable		 4g2zA-1qgdA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		3 / 3 LEU A  70
ILE A  11
ARG A  12
 None
 0.57A 4mk4B-1qgdA:
3.7		 4mk4B-1qgdA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ILE A 162
GLY A 413
ALA A 418
VAL A 166
ILE A 120
 None
 0.89A 4rvdA-1qgdA:
3.2		 4rvdA-1qgdA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 ILE A 162
GLY A 413
ALA A 418
VAL A 166
ILE A 120
 None
 0.89A 4rvgA-1qgdA:
3.4		 4rvgA-1qgdA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 VAL A  19
GLY A  67
TYR A  72
SER A  15
HIS A  66
 None
None
None
None
TPP  A 670 ( 3.8A)
 1.44A 4xueB-1qgdA:
4.0		 4xueB-1qgdA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 TRP A 619
GLY A 540
PHE A 589
ILE A 555
ALA A 556
 None
 1.08A 5j7wD-1qgdA:
undetectable		 5j7wD-1qgdA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ALA A 227
GLY A 218
CYH A 243
LYS A 244
 None
 1.13A 5jliA-1qgdA:
undetectable		 5jliA-1qgdA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 ALA A 227
GLY A 218
CYH A 243
LYS A 244
 None
 1.16A 5jt4A-1qgdA:
undetectable		 5jt4A-1qgdA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 10 TYR A 618
TYR A 622
ILE A 555
TYR A 620
ILE A 629
 None
 1.32A 5mzrA-1qgdA:
undetectable		 5mzrA-1qgdA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 10 TYR A 618
TYR A 622
ILE A 555
TYR A 620
ILE A 629
 None
 1.30A 5mzrC-1qgdA:
undetectable		 5mzrC-1qgdA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 9 HIS A 211
ILE A 213
TYR A 148
ILE A 224
 None
 0.84A 5vkqB-1qgdA:
undetectable
5vkqC-1qgdA:
undetectable		 5vkqB-1qgdA:
16.71
5vkqC-1qgdA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		6 / 12 GLY A 209
GLY A 176
GLY A 171
TRP A 210
ASP A  58
ILE A 179
 None
 1.41A 5wz1B-1qgdA:
undetectable		 5wz1B-1qgdA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 7 ASP A 183
ASP A 155
GLY A 156
ASN A  64
 None
CA  A 675 (-3.3A)
TPP  A 670 ( 3.5A)
None
 1.06A 5x7pA-1qgdA:
0.0		 5x7pA-1qgdA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		5 / 12 GLY A  65
VAL A 109
GLY A 154
ALA A 151
ALA A 180
 None
None
TPP  A 670 ( 4.1A)
None
None
 1.06A 6c2mD-1qgdA:
undetectable		 6c2mD-1qgdA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		4 / 5 GLN A 478
VAL A 438
PRO A 475
THR A 431
 None
 1.48A 6cduI-1qgdA:
0.2
6cduJ-1qgdA:
0.0		 6cduI-1qgdA:
19.41
6cduJ-1qgdA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1qgd PROTEIN
(TRANSKETOLASE)
(Escherichia
coli) 		3 / 3 VAL A 109
GLU A 110
ILE A  71
 None
 0.46A 6f7lB-1qgdA:
undetectable		 6f7lB-1qgdA:
21.45