SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 8 ASN A 224
GLN A 231
ASN A 176
ASP A 172
 None
 1.31A 1rs6A-1qgiA:
undetectable		 1rs6A-1qgiA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 8 ASN A 224
GLN A 231
ASN A 176
ASP A 172
 None
 1.36A 1zzqA-1qgiA:
0.0		 1zzqA-1qgiA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 LEU A  12
LEU A  15
ILE A 167
SER A 152
 None
 0.96A 2hc4A-1qgiA:
undetectable		 2hc4A-1qgiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 VAL A 153
THR A  19
LEU A  21
TRP A 141
 None
 1.20A 3arrA-1qgiA:
undetectable		 3arrA-1qgiA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_A_EDTA802_0
(ALPHA-GLUCOSIDASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 5 ASN A 132
TYR A  47
LYS A  45
ARG A 137
 None
 1.48A 3wfaA-1qgiA:
0.0
3wfaB-1qgiA:
0.0		 3wfaA-1qgiA:
18.23
3wfaB-1qgiA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 6 ARG A 137
ASN A 132
TYR A  47
LYS A  45
 None
 1.49A 3wfaA-1qgiA:
undetectable
3wfaB-1qgiA:
undetectable		 3wfaA-1qgiA:
18.23
3wfaB-1qgiA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		3 / 3 ASN A 227
TRP A 256
ASP A 215
 None
 1.22A 4a7tA-1qgiA:
undetectable
4a7tF-1qgiA:
undetectable		 4a7tA-1qgiA:
22.62
4a7tF-1qgiA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 8 MET A  30
ILE A  33
ASN A  34
GLU A  51
 None
 0.97A 4a97D-1qgiA:
undetectable		 4a97D-1qgiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 ASN A 224
GLN A 231
ASN A 176
ASP A 172
 None
 1.41A 4kcnB-1qgiA:
undetectable		 4kcnB-1qgiA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 8 MET A 109
THR A 143
VAL A 147
PHE A  64
 None
 0.99A 4ltwA-1qgiA:
undetectable		 4ltwA-1qgiA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 6 ILE A  53
ASP A  55
ARG A  57
GLY A  65
 NAG  A 602 ( 4.7A)
None
GCS  A 600 (-3.7A)
GCS  A 601 ( 4.6A)
 0.50A 4oltA-1qgiA:
21.0		 4oltA-1qgiA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 6 ILE A  53
ASP A  55
ARG A  57
GLY A  65
 NAG  A 602 ( 4.7A)
None
GCS  A 600 (-3.7A)
GCS  A 601 ( 4.6A)
 0.55A 4oltB-1qgiA:
20.9		 4oltB-1qgiA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 ARG A  57
THR A  60
GLY A  65
THR A  67
 GCS  A 600 (-3.7A)
GCS  A 601 ( 4.1A)
GCS  A 601 ( 4.6A)
None
 0.46A 4qwpB-1qgiA:
21.1		 4qwpB-1qgiA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPE_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		5 / 11 GLY A  23
ASP A   5
TYR A  47
LYS A  31
ILE A  44
 None
 1.29A 4ypeB-1qgiA:
undetectable		 4ypeB-1qgiA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		3 / 3 ASN A 205
SER A 196
SER A 195
 None
 0.79A 5gsnA-1qgiA:
undetectable		 5gsnA-1qgiA:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWA_A_GCSA301_1
(CHITOSANASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		5 / 8 ILE A  53
ASP A  55
ARG A  57
GLY A  65
THR A  67
 NAG  A 602 ( 4.7A)
None
GCS  A 600 (-3.7A)
GCS  A 601 ( 4.6A)
None
 0.52A 5hwaA-1qgiA:
39.1		 5hwaA-1qgiA:
99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 6 TYR A  85
ASP A  77
GLY A  78
PHE A  82
 None
 1.06A 5nooC-1qgiA:
undetectable		 5nooC-1qgiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 LEU A 190
VAL A 165
GLU A 199
SER A 163
 None
 1.15A 5umwA-1qgiA:
0.0
5umwF-1qgiA:
0.0		 5umwA-1qgiA:
15.12
5umwF-1qgiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		4 / 7 LEU A  81
ALA A  84
ALA A 139
THR A  11
 None
 0.77A 6a7jA-1qgiA:
undetectable		 6a7jA-1qgiA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 1qgi PROTEIN
(CHITOSANASE)
(Bacillus
circulans) 		5 / 9 THR A 180
GLY A 181
GLY A 182
TYR A 151
VAL A 213
 None
 1.13A 6gnfA-1qgiA:
undetectable		 6gnfA-1qgiA:
18.75