SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 HIS A 165
GLY A 168
LEU A 239
ASP A 242
 HEM  A1350 (-3.4A)
HEM  A1350 (-3.5A)
None
None
 0.44A 1aegA-1qgjA:
24.2		 1aegA-1qgjA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 11 ILE A 145
ASN A 154
LEU A 245
TYR A 262
ALA A 160
 None
GSH  A1794 (-3.3A)
None
None
None
 1.32A 1ju6A-1qgjA:
undetectable		 1ju6A-1qgjA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 10 ILE A 145
ASN A 154
LEU A 245
TYR A 262
ALA A 160
 None
GSH  A1794 (-3.3A)
None
None
None
 1.32A 1ju6C-1qgjA:
0.0		 1ju6C-1qgjA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 11 ILE A 145
ASN A 154
LEU A 245
TYR A 262
ALA A 160
 None
GSH  A1794 (-3.3A)
None
None
None
 1.32A 1ju6D-1qgjA:
undetectable		 1ju6D-1qgjA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 4 SER A 109
GLY A 110
HIS A  40
ASP A  96
 None
 1.39A 2oxtC-1qgjA:
undetectable		 2oxtC-1qgjA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 7 SER A 109
ALA A  34
LEU A  36
SER A 105
 None
HEM  A1350 (-3.7A)
None
None
 0.97A 3cfqA-1qgjA:
undetectable
3cfqB-1qgjA:
undetectable		 3cfqA-1qgjA:
20.80
3cfqB-1qgjA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 PRO A  12
ASN A  13
VAL A  91
GLY A  90
 None
 0.61A 3em0B-1qgjA:
undetectable		 3em0B-1qgjA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		3 / 3 ASN A  67
MET A  32
PHE A  74
 None
 0.95A 3g4lD-1qgjA:
0.3		 3g4lD-1qgjA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 10 ALA A 214
LEU A 196
ASN A 199
LEU A 200
VAL A 203
 None
 0.61A 3o02A-1qgjA:
0.0
3o02B-1qgjA:
undetectable		 3o02A-1qgjA:
22.47
3o02B-1qgjA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 10 ALA A  83
VAL A  18
ILE A  97
VAL A  91
ILE A  17
 None
 1.00A 3oxvB-1qgjA:
undetectable		 3oxvB-1qgjA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 11 ALA A  83
VAL A  18
ILE A  97
VAL A  91
ILE A  17
 None
 0.99A 3oxvD-1qgjA:
undetectable		 3oxvD-1qgjA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 10 ALA A  83
VAL A  18
ILE A  97
VAL A  91
ILE A  17
 None
 0.94A 3oxwB-1qgjA:
undetectable		 3oxwB-1qgjA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 12 GLY A 168
ALA A 214
ALA A 170
LEU A 216
SER A 109
 HEM  A1350 (-3.5A)
None
HEM  A1350 (-3.8A)
None
None
 1.06A 3p2kD-1qgjA:
undetectable		 3p2kD-1qgjA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		3 / 3 TYR A 262
ASP A 157
ASP A 272
 None
GSH  A1794 (-4.1A)
GSH  A1794 ( 4.2A)
 0.82A 3r24A-1qgjA:
undetectable		 3r24A-1qgjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 7 ALA A  34
LEU A  36
SER A 105
SER A 109
 HEM  A1350 (-3.7A)
None
None
None
 0.99A 4ikjA-1qgjA:
undetectable
4ikjB-1qgjA:
undetectable		 4ikjA-1qgjA:
20.38
4ikjB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 SER A 109
ALA A  34
LEU A  36
SER A 105
 None
HEM  A1350 (-3.7A)
None
None
 0.95A 4ikjA-1qgjA:
undetectable
4ikjB-1qgjA:
undetectable		 4ikjA-1qgjA:
20.38
4ikjB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 ALA A  34
LEU A  36
SER A 105
SER A 109
 HEM  A1350 (-3.7A)
None
None
None
 0.93A 4ikkA-1qgjA:
undetectable
4ikkB-1qgjA:
undetectable		 4ikkA-1qgjA:
20.38
4ikkB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 7 SER A 109
ALA A  34
LEU A  36
SER A 105
 None
HEM  A1350 (-3.7A)
None
None
 0.95A 4ikkA-1qgjA:
undetectable
4ikkB-1qgjA:
undetectable		 4ikkA-1qgjA:
20.38
4ikkB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 7 ALA A  34
LEU A  36
SER A 105
SER A 109
 HEM  A1350 (-3.7A)
None
None
None
 0.94A 4iklA-1qgjA:
undetectable
4iklB-1qgjA:
undetectable		 4iklA-1qgjA:
20.38
4iklB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 SER A 109
ALA A  34
LEU A  36
SER A 105
 None
HEM  A1350 (-3.7A)
None
None
 0.96A 4iklA-1qgjA:
undetectable
4iklB-1qgjA:
undetectable		 4iklA-1qgjA:
20.38
4iklB-1qgjA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 8 VAL A  22
LEU A  36
ASP A  96
ILE A  97
 None
 0.86A 4lzrA-1qgjA:
undetectable		 4lzrA-1qgjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 8 VAL A 259
LEU A 233
LEU A 232
TYR A 228
ASP A 225
 None
None
None
None
CA  A2002 (-2.9A)
 1.47A 4lzrA-1qgjA:
undetectable		 4lzrA-1qgjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		4 / 5 PHE A 229
HIS A 165
LEU A 239
PRO A 137
 None
HEM  A1350 (-3.4A)
None
HEM  A1350 (-4.2A)
 1.41A 4o8zA-1qgjA:
undetectable		 4o8zA-1qgjA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 12 VAL A 297
GLU A 290
ASN A  47
ARG A 120
ASP A  96
 None
 1.41A 5fhqA-1qgjA:
undetectable		 5fhqA-1qgjA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		3 / 3 LYS A 147
GLN A 128
ASN A 129
 None
 1.09A 5l2tA-1qgjA:
undetectable		 5l2tA-1qgjA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 12 ALA A 160
GLY A 163
SER A 162
LEU A 245
ASP A 217
 None
None
HEM  A1350 (-3.4A)
None
CA  A2002 (-3.3A)
 1.47A 5vlmF-1qgjA:
0.0		 5vlmF-1qgjA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 12 LEU A  53
SER A 105
VAL A  22
ILE A  80
ASP A  78
 None
 1.16A 6bxmA-1qgjA:
undetectable		 6bxmA-1qgjA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 1qgj PEROXIDASE N
(Arabidopsis
thaliana) 		5 / 12 LEU A  53
SER A 105
VAL A  22
ILE A  80
ASP A  78
 None
 1.26A 6bxnA-1qgjA:
undetectable		 6bxnA-1qgjA:
20.83