SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 8 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 1.01A 1os6A-1qgoA:
undetectable		 1os6A-1qgoA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 11 ASN A 225
VAL A 195
GLY A 194
LEU A 197
SER A 219
 None
 1.24A 2bxgA-1qgoA:
undetectable		 2bxgA-1qgoA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 4 LEU A  63
PRO A  62
LEU A  66
ARG A 101
 None
 1.00A 2hrcA-1qgoA:
15.3		 2hrcA-1qgoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		3 / 3 PRO A  62
LEU A  66
ARG A 101
 None
 0.84A 3aqiA-1qgoA:
2.1		 3aqiA-1qgoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 12 ASP A  16
VAL A  23
GLY A  11
LEU A  51
ILE A  47
 None
 0.97A 3ku1H-1qgoA:
2.5		 3ku1H-1qgoA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 12 ILE A  84
ILE A  85
LEU A 114
GLY A 144
ALA A 173
 None
SO4  A 400 ( 4.2A)
None
None
None
 0.96A 3rukB-1qgoA:
undetectable		 3rukB-1qgoA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 8 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 0.97A 3selX-1qgoA:
undetectable		 3selX-1qgoA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 12 LEU A 114
GLY A 144
ILE A  84
ASP A 159
LEU A 127
 None
 0.99A 3uj6A-1qgoA:
undetectable		 3uj6A-1qgoA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 6 CYH A  18
THR A  17
ASN A  21
ILE A  47
 None
 1.26A 3w9tB-1qgoA:
0.0		 3w9tB-1qgoA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 7 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 1.07A 4hbfA-1qgoA:
undetectable		 4hbfA-1qgoA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 7 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 0.98A 4hc3A-1qgoA:
undetectable		 4hc3A-1qgoA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 12 ILE A  84
ILE A  85
LEU A 114
GLY A 144
ALA A 173
 None
SO4  A 400 ( 4.2A)
None
None
None
 0.97A 4nkvB-1qgoA:
undetectable		 4nkvB-1qgoA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A   5
 None
 1.28A 5dzkb-1qgoA:
undetectable
5dzkp-1qgoA:
undetectable		 5dzkb-1qgoA:
21.11
5dzkp-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A  29
 None
 1.30A 5dzkb-1qgoA:
undetectable
5dzkp-1qgoA:
undetectable		 5dzkb-1qgoA:
21.11
5dzkp-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 6 SER A  32
ALA A  31
HIS A 253
LEU A  29
 None
 1.27A 5dzkB-1qgoA:
0.0
5dzkP-1qgoA:
undetectable		 5dzkB-1qgoA:
21.11
5dzkP-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A   5
 None
 1.29A 5dzkc-1qgoA:
undetectable
5dzkq-1qgoA:
undetectable		 5dzkc-1qgoA:
21.11
5dzkq-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A  29
 None
 1.28A 5dzkc-1qgoA:
undetectable
5dzkq-1qgoA:
undetectable		 5dzkc-1qgoA:
21.11
5dzkq-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A   5
 None
 1.21A 5dzkf-1qgoA:
2.1
5dzkt-1qgoA:
undetectable		 5dzkf-1qgoA:
21.11
5dzkt-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 5 SER A  32
ALA A  31
HIS A 253
LEU A  29
 None
 1.20A 5dzkf-1qgoA:
2.1
5dzkt-1qgoA:
undetectable		 5dzkf-1qgoA:
21.11
5dzkt-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		4 / 6 SER A  32
ALA A  31
HIS A 253
LEU A   5
 None
 1.24A 5dzkg-1qgoA:
undetectable
5dzku-1qgoA:
undetectable		 5dzkg-1qgoA:
21.11
5dzku-1qgoA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE
(Salmonella
enterica) 		5 / 12 ILE A  22
GLY A  11
SER A   9
VAL A 174
PRO A 199
 None
None
None
SO4  A 401 (-3.9A)
None
 1.22A 5ergB-1qgoA:
undetectable		 5ergB-1qgoA:
21.54