SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qgr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 11 ILE A 713
ASP A 719
GLY A 718
PHE A 717
VAL A 674
 None
 1.43A 1axwB-1qgrA:
undetectable		 1axwB-1qgrA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 772
PHE A 717
GLY A 718
SER A 764
LEU A 700
 None
 1.35A 1fm6X-1qgrA:
undetectable		 1fm6X-1qgrA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		5 / 10 GLY A 771
MET B  47
GLN A 774
ARG B  50
GLY A 775
 None
 1.27A 1fohB-1qgrA:
0.0		 1fohB-1qgrA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 GLN A 712
ARG A 679
LEU A 654
SER A 633
 None
 0.95A 1hk3A-1qgrA:
0.0		 1hk3A-1qgrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 6 SER A  67
THR A  66
ASN A  63
LEU A  59
 None
 1.08A 1mxdA-1qgrA:
undetectable		 1mxdA-1qgrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 SER A  67
THR A  66
ASN A  63
LEU A  59
 None
 1.02A 1mxgA-1qgrA:
undetectable		 1mxgA-1qgrA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 THR A 150
LEU A 151
LEU A 198
 None
 0.55A 1mz9C-1qgrA:
undetectable		 1mz9C-1qgrA:
4.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		5 / 10 GLY A 771
MET B  47
GLN A 774
ARG B  50
GLY A 775
 None
 1.27A 1pn0B-1qgrA:
undetectable		 1pn0B-1qgrA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		5 / 10 GLY A 771
MET B  47
GLN A 774
ARG B  50
GLY A 775
 None
 1.20A 1pn0C-1qgrA:
undetectable		 1pn0C-1qgrA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		5 / 10 GLY A 771
MET B  47
GLN A 774
ARG B  50
GLY A 775
 None
 1.21A 1pn0D-1qgrA:
0.0		 1pn0D-1qgrA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 4 LEU A 510
LEU A 505
SER A 502
LEU A 453
 None
 1.10A 1ya3A-1qgrA:
0.0		 1ya3A-1qgrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 SER A 421
ASP A 337
CYH A 345
 None
 1.03A 2br4E-1qgrA:
undetectable		 2br4E-1qgrA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 720
VAL A 674
GLY A 675
CYH A 678
LEU A 696
 None
 1.12A 2bxeB-1qgrA:
0.3		 2bxeB-1qgrA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 GLY A 775
GLY A 726
GLY A 725
ALA A 721
PRO A 785
 None
 0.90A 2dpmA-1qgrA:
undetectable		 2dpmA-1qgrA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 5 ASP A 230
LEU A 192
LYS A 191
ARG A 232
 None
 1.35A 2gj5A-1qgrA:
undetectable		 2gj5A-1qgrA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASP A 288
ASN A 285
THR A 264
 None
 0.81A 2q63B-1qgrA:
undetectable		 2q63B-1qgrA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 LEU A 192
ASN A 188
ARG A 232
 None
 0.83A 2qhfA-1qgrA:
undetectable		 2qhfA-1qgrA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 GLU A 626
GLN A 665
VAL A 705
HIS A 706
 None
 1.18A 3b9lA-1qgrA:
2.6		 3b9lA-1qgrA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 6 ASP A 579
ARG A 525
ARG A 574
SER A 621
 None
 1.31A 3ckzA-1qgrA:
undetectable		 3ckzA-1qgrA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASN A  63
ASP A 160
GLN A 159
 None
 0.83A 3eeyC-1qgrA:
undetectable		 3eeyC-1qgrA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASN A  63
ASP A 160
GLN A 159
 None
 0.84A 3eeyD-1qgrA:
undetectable		 3eeyD-1qgrA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASN A  63
ASP A 160
GLN A 159
 None
 0.83A 3eeyE-1qgrA:
undetectable		 3eeyE-1qgrA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A  61
ALA A  57
LEU A   3
ASN A  32
LEU A  33
 None
 1.34A 3eigA-1qgrA:
undetectable		 3eigA-1qgrA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 GLU A 763
VAL A 814
CYH A 817
 None
 0.79A 3fbxA-1qgrA:
0.0		 3fbxA-1qgrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 11 ALA A 153
LEU A 129
ILE A 161
LEU A 166
THR A 150
 None
 1.21A 3fl9C-1qgrA:
undetectable		 3fl9C-1qgrA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 9 ALA A 745
LEU A 758
ILE A 804
LEU A 766
PHE A 800
 None
 1.29A 3fl9D-1qgrA:
undetectable		 3fl9D-1qgrA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 10 ALA A 745
LEU A 758
ILE A 804
LEU A 766
PHE A 800
 None
 1.16A 3fl9E-1qgrA:
undetectable		 3fl9E-1qgrA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 LEU A 732
GLY A 718
VAL A 716
LEU A 658
VAL A 674
 None
 1.04A 3frqB-1qgrA:
undetectable		 3frqB-1qgrA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 THR A 143
GLY A 100
LEU A 129
VAL A 113
ILE A 157
 None
 0.96A 3frqB-1qgrA:
undetectable		 3frqB-1qgrA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASP A 579
LEU A 583
GLN A 589
 None
 0.78A 3g4lA-1qgrA:
undetectable		 3g4lA-1qgrA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 LEU A 635
THR A 634
ALA A 586
ILE A 554
 None
 0.83A 3jusB-1qgrA:
undetectable		 3jusB-1qgrA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASN A 343
ASP A 337
ARG B  29
 None
 0.80A 3k13C-1qgrA:
undetectable		 3k13C-1qgrA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 GLU A 530
LEU A 583
THR A 587
ALA A 586
 None
 1.30A 3mbgA-1qgrA:
0.0
3mbgB-1qgrA:
0.0		 3mbgA-1qgrA:
9.02
3mbgB-1qgrA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ALA A 176
ALA A 194
THR A 195
LEU A 198
LEU A 241
 None
 1.03A 3r9cA-1qgrA:
0.0		 3r9cA-1qgrA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 8 ALA A 818
ILE A 801
LEU A 846
ALA A 865
ALA A 862
 None
 1.23A 3r9tA-1qgrA:
undetectable		 3r9tA-1qgrA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 ILE A 801
LEU A 846
ALA A 865
ALA A 862
 None
 0.89A 3r9tB-1qgrA:
undetectable		 3r9tB-1qgrA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 PHE A 829
TYR A 769
LEU A 834
 None
 0.70A 3sueB-1qgrA:
undetectable		 3sueB-1qgrA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 10 LEU A 588
THR A 587
VAL A 591
LEU A 552
THR A 550
 None
 1.21A 3tbgC-1qgrA:
0.0		 3tbgC-1qgrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ASN A 189
GLU A 148
ARG A 105
 None
 1.02A 3wxoA-1qgrA:
0.0		 3wxoA-1qgrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		4 / 6 GLN A 589
ARG A 593
GLU A 760
LEU B  38
 None
 1.17A 4ax8A-1qgrA:
0.6		 4ax8A-1qgrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1qgr PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 10 SER A 715
ASP A 676
ARG A 679
ASN B  35
GLU A 626
 None
 1.46A 4fevA-1qgrA:
0.5		 4fevA-1qgrA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 PHE A 503
TYR A 482
TYR A 497
 None
 1.10A 4ffwA-1qgrA:
undetectable		 4ffwA-1qgrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ARG A 870
LYS A 871
LYS A 867
 None
 1.42A 4k50E-1qgrA:
2.3		 4k50E-1qgrA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 LEU A 166
ILE A 157
GLU A 172
ILE A 173
ALA A 176
 None
 0.93A 4ltwA-1qgrA:
undetectable		 4ltwA-1qgrA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 1qgr PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 SER A 715
ASP A 719
GLN B  46
 None
 0.84A 4oltA-1qgrA:
1.7
4oltB-1qgrA:
2.0		 4oltA-1qgrA:
15.15
4oltB-1qgrA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 HIS A 810
ASN A 759
VAL A 815
ALA A 818
 None
 0.67A 4p6sA-1qgrA:
undetectable		 4p6sA-1qgrA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ASN A 469
VAL A 470
MET A 417
LEU A 413
GLY A 391
 None
 1.02A 4qckA-1qgrA:
0.0		 4qckA-1qgrA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 1qgr PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 GLN B  46
SER A 715
ASP A 719
 None
 0.91A 4qwpA-1qgrB:
undetectable
4qwpB-1qgrB:
undetectable		 4qwpA-1qgrB:
8.37
4qwpB-1qgrB:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 9 ILE A 393
GLY A 349
ALA A 348
THR A 329
VAL A 323
 None
 1.22A 4r1zA-1qgrA:
undetectable		 4r1zA-1qgrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 GLY A 100
GLU A 102
GLU A 152
ALA A 193
 None
 0.74A 4rjdA-1qgrA:
undetectable
4rjdB-1qgrA:
undetectable		 4rjdA-1qgrA:
6.05
4rjdB-1qgrA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 VAL A 424
LEU A 416
VAL A 387
 None
 0.50A 4wq4A-1qgrA:
undetectable		 4wq4A-1qgrA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 5 LEU A 821
ALA A 768
LEU A 766
VAL A 735
 None
 1.19A 5cr1A-1qgrA:
undetectable		 5cr1A-1qgrA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ALA A 237
ASN A 240
LEU A 241
 None
 0.38A 5i1nB-1qgrA:
0.0		 5i1nB-1qgrA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		3 / 3 ALA A 237
ASN A 240
LEU A 241
 None
 0.45A 5i1oA-1qgrA:
undetectable		 5i1oA-1qgrA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 HIS A 810
ASN A 759
VAL A 815
ALA A 818
 None
 0.67A 5i3aA-1qgrA:
undetectable		 5i3aA-1qgrA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 HIS A 810
ASN A 759
VAL A 815
ALA A 818
 None
 0.71A 5i3aB-1qgrA:
undetectable		 5i3aB-1qgrA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 HIS A 810
ASN A 759
VAL A 815
ALA A 818
 None
 0.68A 5i3bA-1qgrA:
undetectable		 5i3bA-1qgrA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 134
VAL A 137
ILE A 116
ALA A 117
 None
 0.91A 5n0sA-1qgrA:
undetectable		 5n0sA-1qgrA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 134
VAL A 137
ILE A 116
ALA A 117
 None
 0.91A 5n0sB-1qgrA:
undetectable		 5n0sB-1qgrA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 137
GLN A 132
ILE A 116
ALA A 117
 None
 1.03A 5n0sB-1qgrA:
undetectable		 5n0sB-1qgrA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 134
VAL A 137
ILE A 116
ALA A 117
 None
 0.85A 5n0tA-1qgrA:
undetectable		 5n0tA-1qgrA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 134
VAL A 137
ILE A 116
ALA A 117
 None
 0.89A 5n0wB-1qgrA:
undetectable		 5n0wB-1qgrA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 ILE A 157
VAL A 134
VAL A 137
ILE A 116
ALA A 117
 None
 0.89A 5n4iA-1qgrA:
undetectable		 5n4iA-1qgrA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		5 / 12 CYH A 765
TYR A 757
LEU A 758
ILE A 804
LEU A 700
 None
 1.50A 5ycpA-1qgrA:
0.0		 5ycpA-1qgrA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 8 ASN A 578
GLN A 576
PHE A 577
ASP A 573
 None
 1.21A 6auuB-1qgrA:
0.0		 6auuB-1qgrA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
(Homo
sapiens) 		4 / 7 HIS A 803
GLY A 806
ARG A 762
LEU A 758
 None
 1.03A 6btxA-1qgrA:
0.7		 6btxA-1qgrA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA717_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)
(Homo
sapiens;
Homo
sapiens) 		4 / 5 SER A 633
ASP A 676
ARG B  39
LYS B  42
 None
 1.19A 6dwdA-1qgrA:
0.0		 6dwdA-1qgrA:
19.96