SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 7 LEU B 236
LEU B 316
GLY B 482
LEU B 324
 None
 0.82A 1gtiA-1qh1B:
0.1		 1gtiA-1qh1B:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 8 ASN B 441
LEU B 469
LEU B 462
LEU B 423
 None
 1.22A 1hk2A-1qh1B:
undetectable		 1hk2A-1qh1B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		3 / 3 THR B 321
LEU B 325
VAL B 328
 None
 0.67A 1mz9E-1qh1B:
undetectable		 1mz9E-1qh1B:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 11 GLY B 374
MET B 351
LEU B 318
ALA B 320
ALA B 319
 None
 1.00A 1x7pA-1qh1B:
2.4
1x7pB-1qh1B:
2.0		 1x7pA-1qh1B:
20.84
1x7pB-1qh1B:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 LEU B 220
LEU B 289
LEU B 324
VAL B 328
THR B 310
 None
 1.12A 2w9gA-1qh1B:
undetectable		 2w9gA-1qh1B:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 12 HIS B 191
GLY B 466
ASP B 368
ILE B 439
VAL B 372
 None
 0.97A 3bwcB-1qh1B:
3.2		 3bwcB-1qh1B:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 12 ALA B 486
GLU B 381
LEU B 406
LEU B 375
GLY B 374
 None
 1.00A 3k2hA-1qh1B:
undetectable		 3k2hA-1qh1B:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 12 ALA B 486
GLU B 381
LEU B 406
LEU B 375
GLY B 374
 None
 1.00A 3k2hB-1qh1B:
0.0		 3k2hB-1qh1B:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 THR B 480
GLY B 482
GLU B 484
LEU B 316
ILE B 314
 None
 1.26A 3kvrB-1qh1B:
undetectable		 3kvrB-1qh1B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 5 ASP B 114
SER B 113
VAL B  94
GLY B  89
 None
 1.06A 3rxhA-1qh1B:
undetectable		 3rxhA-1qh1B:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 7 ALA B 486
TYR B 483
ARG B 346
ARG B 238
 None
 1.03A 3twpC-1qh1B:
3.3		 3twpC-1qh1B:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 7 ARG B 377
ALA B 320
TRP B 481
ALA B 313
 None
 1.42A 3tx2A-1qh1B:
0.0		 3tx2A-1qh1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 ALA B 496
LEU B 465
LEU B 493
ASN B 488
ILE B 489
 None
 0.97A 3wdmB-1qh1B:
2.2		 3wdmB-1qh1B:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 9 ALA B 496
LEU B 465
LEU B 493
ASN B 488
ILE B 489
 None
 0.96A 3wdmC-1qh1B:
1.9		 3wdmC-1qh1B:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 ALA B 496
LEU B 465
LEU B 493
ASN B 488
ILE B 489
 None
 1.07A 3wdmD-1qh1B:
undetectable		 3wdmD-1qh1B:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 7 ASP B 285
LEU B 222
GLN B 290
LEU B 294
 None
 1.06A 4ib4A-1qh1B:
1.0		 4ib4A-1qh1B:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 12 ILE B 439
LEU B 493
GLY B 466
HIS B 104
GLY B 440
 None
 1.03A 5l6eA-1qh1B:
undetectable		 5l6eA-1qh1B:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 4 GLN B 478
THR B 479
GLU B 227
LEU B 257
 None
 1.23A 5m66A-1qh1B:
3.6		 5m66A-1qh1B:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		4 / 8 GLY B  72
ASP B 368
PHE B 226
PHE B 101
 None
 0.98A 5mvsB-1qh1B:
3.4		 5mvsB-1qh1B:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 9 LEU B 465
ILE B 463
GLY B 444
LEU B 375
LEU B 365
 None
 0.96A 5o96A-1qh1B:
2.6
5o96B-1qh1B:
2.7		 5o96A-1qh1B:
19.39
5o96B-1qh1B:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_A_CP6A704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 VAL B 147
HIS B  88
THR B 205
VAL B 179
THR B 149
 None
 1.38A 6aogA-1qh1B:
undetectable		 6aogA-1qh1B:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_B_CP6B704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 10 VAL B 147
HIS B  88
THR B 205
VAL B 179
THR B 149
 None
 1.35A 6aogB-1qh1B:
2.6		 6aogB-1qh1B:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 11 SER B 148
THR B 149
LEU B 133
ALA B 153
VAL B 112
 None
 1.29A 6dryA-1qh1B:
undetectable		 6dryA-1qh1B:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1qh1 PROTEIN (NITROGENASE
MOLYBDENUM IRON
PROTEIN)
(Klebsiella
pneumoniae) 		5 / 11 VAL B 147
SER B 148
THR B 149
LEU B 133
VAL B 112
 None
 1.36A 6dryA-1qh1B:
undetectable		 6dryA-1qh1B:
23.74