SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qh4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 8 ALA A  76
LEU A  88
HIS A  97
LEU A 287
 None
 0.89A 1ereE-1qh4A:
undetectable		 1ereE-1qh4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 8 ALA A  76
LEU A  88
HIS A  97
LEU A 287
 None
 0.88A 1ereF-1qh4A:
undetectable		 1ereF-1qh4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 6 PRO A 144
MET A 207
GLU A 231
GLU A 232
 None
 1.43A 1qhyA-1qh4A:
undetectable		 1qhyA-1qh4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 8 LEU A 317
VAL A 295
GLY A 294
LEU A 360
 None
 0.94A 1s1xA-1qh4A:
3.2		 1s1xA-1qh4A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 12 LEU A 162
LEU A 165
ILE A 260
THR A 224
LEU A 226
 None
 1.06A 2bdmA-1qh4A:
undetectable		 2bdmA-1qh4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 8 ILE A 297
LEU A 299
ARG A 320
LEU A 312
 None
 0.84A 2einA-1qh4A:
undetectable
2einJ-1qh4A:
undetectable		 2einA-1qh4A:
20.15
2einJ-1qh4A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 7 HIS A 106
ASN A 274
GLY A 288
TYR A 279
 None
 0.94A 2f6dA-1qh4A:
undetectable		 2f6dA-1qh4A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		3 / 3 ARG A 209
GLU A 155
SER A 205
 None
 0.78A 2xkkA-1qh4A:
undetectable
2xkkC-1qh4A:
1.8		 2xkkA-1qh4A:
19.53
2xkkC-1qh4A:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 6 THR A  71
VAL A  72
CYH A 283
SER A 285
 ACT  A1502 (-4.6A)
ACT  A1502 (-3.6A)
ACT  A1502 ( 4.1A)
ACT  A1502 ( 3.8A)
 0.28A 3b6rB-1qh4A:
53.9		 3b6rB-1qh4A:
90.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 5 ILE A  93
HIS A  97
TYR A  82
GLY A 288
 None
 1.16A 3b9mA-1qh4A:
1.1		 3b9mA-1qh4A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 7 VAL A 354
LYS A 358
ILE A 361
ARG A 366
 None
 0.68A 3bjwB-1qh4A:
undetectable		 3bjwB-1qh4A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA303_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 4 ARG A  45
VAL A  84
LYS A  86
GLU A  87
 None
 1.20A 3deuA-1qh4A:
1.2		 3deuA-1qh4A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 8 ARG A 130
LEU A 121
LEU A 317
ILE A 361
 None
 0.95A 3ln1A-1qh4A:
undetectable		 3ln1A-1qh4A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 7 ARG A 130
LEU A 121
LEU A 317
ILE A 361
 None
 0.94A 3ln1B-1qh4A:
undetectable		 3ln1B-1qh4A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 7 ASN A  28
MET A  30
LEU A  88
LEU A  23
 None
 1.29A 3nk2X-1qh4A:
undetectable		 3nk2X-1qh4A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 11 ALA A 339
VAL A 336
GLY A 294
ALA A 293
LEU A 312
 None
 1.04A 3sm2B-1qh4A:
undetectable		 3sm2B-1qh4A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 9 PHE A 225
VAL A 227
PHE A 271
GLY A 134
PHE A 264
 None
 1.18A 3t3rB-1qh4A:
0.0		 3t3rB-1qh4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 9 PHE A 225
VAL A 227
PHE A 271
GLY A 134
PHE A 264
 None
 1.20A 3t3rC-1qh4A:
0.0		 3t3rC-1qh4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 10 PHE A 225
VAL A 227
PHE A 271
GLY A 134
PHE A 264
 None
 1.21A 3t3rD-1qh4A:
0.0		 3t3rD-1qh4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		3 / 3 ASP A  78
ARG A 209
THR A  47
 None
 0.83A 4i13A-1qh4A:
undetectable		 4i13A-1qh4A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 5 GLY A 163
SER A 164
ALA A 161
GLU A 160
 None
 0.98A 4m93B-1qh4A:
undetectable
4m93C-1qh4A:
undetectable		 4m93B-1qh4A:
21.56
4m93C-1qh4A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		3 / 3 ASP A  78
ARG A 209
THR A  47
 None
 0.84A 4p3rA-1qh4A:
undetectable		 4p3rA-1qh4A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 12 THR A 282
ALA A  76
LEU A  88
HIS A  97
LEU A 287
 None
 1.11A 4xi3D-1qh4A:
undetectable		 4xi3D-1qh4A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		3 / 3 THR A 180
ASP A 181
ALA A 182
 None
 0.08A 5g5gB-1qh4A:
undetectable		 5g5gB-1qh4A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 12 GLU A 232
LEU A 142
GLY A 134
ASN A 286
LEU A 287
 None
 1.12A 5kbwA-1qh4A:
undetectable		 5kbwA-1qh4A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 12 GLU A 232
LEU A 142
GLY A 134
ASN A 286
LEU A 287
 None
 1.15A 5kc4E-1qh4A:
undetectable		 5kc4E-1qh4A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		5 / 12 VAL A 353
LEU A 110
ALA A 293
SER A 337
ARG A 316
 None
 1.41A 5syfB-1qh4A:
undetectable		 5syfB-1qh4A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1qh4 CREATINE KINASE
(Gallus
gallus) 		4 / 7 ILE A 297
LEU A 299
ARG A 320
LEU A 312
 None
 0.90A 5xdqN-1qh4A:
0.0
5xdqW-1qh4A:
0.0		 5xdqN-1qh4A:
20.15
5xdqW-1qh4A:
10.03