SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1qh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 GLY A  61
ALA A  84
HIS A  55
THR A  52
 None
 0.83A 1c9sT-1qh5A:
undetectable
1c9sU-1qh5A:
undetectable		 1c9sT-1qh5A:
14.90
1c9sU-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 PRO A  30
GLY A 133
ASP A 134
PHE A 137
VAL A 138
 None
None
ZN  A 262 ( 2.4A)
GSH  A 463 (-4.9A)
None
 1.03A 1ffyA-1qh5A:
undetectable		 1ffyA-1qh5A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 GLY A  61
ALA A  84
HIS A  55
THR A  52
 None
 0.87A 1gtfL-1qh5A:
undetectable
1gtfM-1qh5A:
undetectable		 1gtfL-1qh5A:
14.90
1gtfM-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 GLY A  61
ALA A  84
HIS A  55
THR A  52
 None
 0.87A 1gtfN-1qh5A:
undetectable
1gtfO-1qh5A:
undetectable		 1gtfN-1qh5A:
14.90
1gtfO-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 TYR A 221
LYS A 196
LEU A 136
SER A 213
 None
 1.11A 1hk2A-1qh5A:
0.0		 1hk2A-1qh5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 TYR A 221
LYS A 196
LEU A 136
SER A 213
 None
 1.13A 1hk3A-1qh5A:
undetectable		 1hk3A-1qh5A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 PRO A  30
GLY A 133
ASP A 134
PHE A 137
VAL A 138
 None
None
ZN  A 262 ( 2.4A)
GSH  A 463 (-4.9A)
None
 1.03A 1qu2A-1qh5A:
undetectable		 1qu2A-1qh5A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 TYR A  13
ASP A  58
THR A 176
TYR A 175
 None
ZN  A 262 (-2.7A)
None
GSH  A 463 (-4.5A)
 1.12A 1rmtD-1qh5A:
undetectable		 1rmtD-1qh5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		3 / 3 LYS A 103
ILE A 115
THR A  49
 None
 0.85A 1rx3A-1qh5A:
undetectable		 1rx3A-1qh5A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 ASP A  79
HIS A  59
HIS A  54
ASP A  58
HIS A  56
 None
ZN  A 262 ( 3.3A)
ZN  A 261 ( 3.4A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.3A)
 1.41A 1t69A-1qh5A:
undetectable		 1t69A-1qh5A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 6 LYS A 201
LEU A 197
ALA A 200
THR A 210
 None
 1.18A 1tyrA-1qh5A:
undetectable		 1tyrA-1qh5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 11 ASP A  58
HIS A  59
HIS A 110
ASP A 134
HIS A 173
 ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 ( 2.4A)
ZN  A 262 (-3.3A)
 0.41A 2q0jB-1qh5A:
15.4		 2q0jB-1qh5A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 GLY A  83
GLU A  64
GLY A  61
ALA A  60
 None
 0.61A 3aruA-1qh5A:
undetectable		 3aruA-1qh5A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 VAL A 130
ILE A 115
GLY A  78
LEU A  85
 None
 0.82A 3bjwB-1qh5A:
undetectable		 3bjwB-1qh5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 VAL A 130
ILE A 115
GLY A  78
LEU A  85
 None
 0.82A 3bjwH-1qh5A:
undetectable		 3bjwH-1qh5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 6 ASP A  79
HIS A  59
HIS A  54
ASP A  58
HIS A  56
 None
ZN  A 262 ( 3.3A)
ZN  A 261 ( 3.4A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.3A)
 1.36A 3c0zC-1qh5A:
undetectable		 3c0zC-1qh5A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 4 MET A 152
LYS A 143
ASN A 222
THR A 107
 None
GSH  A 463 (-2.9A)
None
None
 1.27A 3datA-1qh5A:
0.0		 3datA-1qh5A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 GLU A 174
LEU A 180
TYR A 221
LEU A 136
 None
 1.03A 3qeoB-1qh5A:
undetectable		 3qeoB-1qh5A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		3 / 3 SER A  99
GLY A  98
GLN A  96
 None
 0.64A 3v4tH-1qh5A:
undetectable		 3v4tH-1qh5A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 10 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.67A 4c1dB-1qh5A:
4.0		 4c1dB-1qh5A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.74A 4c1fA-1qh5A:
16.3
4c1fB-1qh5A:
15.3		 4c1fA-1qh5A:
24.82
4c1fB-1qh5A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 9 HIS A  54
HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.68A 4c1hA-1qh5A:
16.4		 4c1hA-1qh5A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 9 HIS A  56
ASP A  58
HIS A  54
GLY A 142
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 ( 3.4A)
GSH  A 463 (-3.5A)
ZN  A 262 (-3.3A)
 1.01A 4c1hA-1qh5A:
16.4		 4c1hA-1qh5A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 5 LEU A 163
LEU A 215
MET A 225
THR A 132
 None
 1.39A 4do3A-1qh5A:
undetectable		 4do3A-1qh5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 7 ALA A  60
GLY A  61
GLY A  83
ILE A  82
 None
 0.63A 4eatA-1qh5A:
undetectable		 4eatA-1qh5A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.69A 4exsB-1qh5A:
2.3		 4exsB-1qh5A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		3 / 3 LYS A 103
ILE A 115
THR A  49
 None
 0.83A 4gh8A-1qh5A:
undetectable		 4gh8A-1qh5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 8 SER A 213
LYS A 201
LEU A 197
ALA A 200
THR A 210
 None
 1.32A 4ikjA-1qh5A:
undetectable
4ikjB-1qh5A:
undetectable		 4ikjA-1qh5A:
19.47
4ikjB-1qh5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 8 LYS A 201
LEU A 197
ALA A 200
THR A 210
SER A 213
 None
 1.42A 4ikkA-1qh5A:
undetectable
4ikkB-1qh5A:
undetectable		 4ikkA-1qh5A:
19.47
4ikkB-1qh5A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 TYR A 221
LYS A 196
GLY A 161
LEU A 136
SER A 213
 None
 1.36A 4ot2A-1qh5A:
undetectable		 4ot2A-1qh5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.70A 5a5zA-1qh5A:
4.7		 5a5zA-1qh5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		6 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A  59
HIS A 110
ARG A 249
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
GSH  A 463 (-2.8A)
 0.78A 5ayaA-1qh5A:
15.7		 5ayaA-1qh5A:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		6 / 11 HIS A  54
HIS A  56
ASP A  58
HIS A  59
HIS A 110
HIS A 173
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.29A 5ayaA-1qh5A:
15.7		 5ayaA-1qh5A:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 9 THR A  48
LEU A 100
VAL A  97
GLY A  98
VAL A  45
 None
 1.34A 5cp4A-1qh5A:
0.0		 5cp4A-1qh5A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.86A 5eevL-1qh5A:
undetectable
5eevV-1qh5A:
undetectable		 5eevL-1qh5A:
14.90
5eevV-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.86A 5eewL-1qh5A:
undetectable
5eewV-1qh5A:
undetectable		 5eewL-1qh5A:
14.90
5eewV-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.85A 5eezL-1qh5A:
undetectable
5eezV-1qh5A:
undetectable		 5eezL-1qh5A:
14.90
5eezV-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.85A 5ef1L-1qh5A:
undetectable
5ef1V-1qh5A:
undetectable		 5ef1L-1qh5A:
14.90
5ef1V-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.85A 5ef2L-1qh5A:
undetectable
5ef2V-1qh5A:
undetectable		 5ef2L-1qh5A:
14.90
5ef2V-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 THR A  52
GLY A  61
ALA A  84
HIS A  55
 None
 0.85A 5ef3L-1qh5A:
undetectable
5ef3V-1qh5A:
undetectable		 5ef3L-1qh5A:
14.90
5ef3V-1qh5A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		3 / 3 ASN A 179
ASP A 134
GLY A 133
 None
ZN  A 262 ( 2.4A)
None
 0.64A 5fctB-1qh5A:
undetectable		 5fctB-1qh5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 ILE A  89
ALA A  25
ALA A  26
VAL A  28
LEU A  47
 None
 1.29A 5igpA-1qh5A:
undetectable		 5igpA-1qh5A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 12 ILE A 115
VAL A  28
ALA A  25
ALA A  26
GLY A  98
 None
 1.43A 5igpA-1qh5A:
undetectable		 5igpA-1qh5A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 10 HIS A  54
HIS A  56
HIS A  59
HIS A 110
ASP A 134
 ZN  A 261 ( 3.4A)
ZN  A 261 ( 3.3A)
ZN  A 262 ( 3.3A)
ZN  A 261 (-3.3A)
ZN  A 262 ( 2.4A)
 0.30A 5nzwA-1qh5A:
6.5		 5nzwA-1qh5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 6 PRO A  30
GLY A  62
LEU A  69
VAL A  36
 None
 0.99A 5x80A-1qh5A:
0.0
5x80B-1qh5A:
0.0		 5x80A-1qh5A:
20.15
5x80B-1qh5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		4 / 8 HIS A  56
ASP A  58
HIS A 110
HIS A 173
 ZN  A 261 ( 3.3A)
ZN  A 262 (-2.7A)
ZN  A 261 (-3.3A)
ZN  A 262 (-3.3A)
 0.75A 5zj8A-1qh5A:
15.8		 5zj8A-1qh5A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 11 TYR A  15
VAL A  28
ALA A  84
ASN A  12
VAL A  31
 None
None
None
ZN  A 262 ( 4.6A)
None
 1.26A 6hu9A-1qh5A:
0.0
6hu9E-1qh5A:
undetectable
6hu9I-1qh5A:
0.0		 6hu9A-1qh5A:
21.44
6hu9E-1qh5A:
21.67
6hu9I-1qh5A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)
(Homo
sapiens) 		5 / 10 TYR A  15
VAL A  28
ALA A  84
ASN A  12
VAL A  31
 None
None
None
ZN  A 262 ( 4.6A)
None
 1.30A 6hu9L-1qh5A:
0.0
6hu9P-1qh5A:
0.0
6hu9T-1qh5A:
0.0		 6hu9L-1qh5A:
21.44
6hu9P-1qh5A:
21.67
6hu9T-1qh5A:
13.55